2010
A potential role for intragenic miRNAs on their hosts' interactome
Hinske L, Galante P, Kuo W, Ohno-Machado L. A potential role for intragenic miRNAs on their hosts' interactome. BMC Genomics 2010, 11: 533. PMID: 20920310, PMCID: PMC3091682, DOI: 10.1186/1471-2164-11-533.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiasCarcinoma, Non-Small-Cell LungConserved SequenceGene Expression Regulation, NeoplasticGenome, HumanHumansIntronsLung NeoplasmsMicroRNAsOpen Reading FramesConceptsIntragenic miRNAsHost genesAdenylate/uridylate-rich elementsMiRNA targetsMRNA targetsHost interactomeGene cohortsMiRNA biogenesis pathwayNon-coding RNA moleculesHigh-confidence setMiRNA target genesProtein-coding regionsKEGG pathway analysisTight regulatory controlNegative feedback regulatorIntronic miRNAsMore intronsBiogenesis pathwayMiRNA genesNegative feedback loopUridylate-rich elementsCellular homeostasisTarget genesRNA moleculesInteractome
2003
An Epicurean learning approach to gene-expression data classification
Albrecht A, Vinterbo S, Ohno-Machado L. An Epicurean learning approach to gene-expression data classification. Artificial Intelligence In Medicine 2003, 28: 75-87. PMID: 12850314, DOI: 10.1016/s0933-3657(03)00036-8.Peer-Reviewed Original ResearchClassification and identification of genes associated with oral cancer based on gene expression profiles. A preliminary study.
Kuo W, Hasina R, Ohno-Machado L, Lingen M. Classification and identification of genes associated with oral cancer based on gene expression profiles. A preliminary study. Dental Journal 2003, 69: 23-6. PMID: 12703240.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Squamous CellGene Expression ProfilingGene Expression Regulation, NeoplasticHuman Genome ProjectHumansMatched-Pair AnalysisMouth NeoplasmsOligonucleotide Array Sequence AnalysisConceptsGene expression profilesHuman Genome ProjectOral squamous cell carcinomaExpression profilesIdentification of genesGenome ProjectDNA microarraysMolecular networksFive-year survival rateSquamous cell carcinomaCurrent treatment strategiesGenesAggressive malignancyCell carcinomaOral cancerPreliminary studyTreatment strategiesCytologic changesEarly diagnosisSurvival rateCancerMicroarrayStatistical algorithmsCarcinomaMalignancy
2002
Analysis of matched mRNA measurements from two different microarray technologies
Kuo W, Jenssen T, Butte A, Ohno-Machado L, Kohane I. Analysis of matched mRNA measurements from two different microarray technologies. Bioinformatics 2002, 18: 405-412. PMID: 11934739, DOI: 10.1093/bioinformatics/18.3.405.Peer-Reviewed Original Research