2020
Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey
Datta R, Topal J, McManus D, Sanft T, Dembry LM, Morrison LJ, Quagliarello V, Juthani-Mehta M. Education needed to improve antimicrobial use during end-of-life care of older adults with advanced cancer: A cross-sectional survey. Palliative Medicine 2020, 35: 236-241. PMID: 32928066, DOI: 10.1177/0269216320956811.Peer-Reviewed Original ResearchConceptsEscalation of careAdvance care planningLife careAdvanced cancerCross-sectional surveyIntravenous antimicrobialsOlder adultsAntimicrobial useCare planningSingle-center cross-sectional surveyEducational interventionAdvance care plansRole of antimicrobialsClinical deteriorationPercent of respondentsAdverse eventsOral antimicrobialsMedicine subspecialistsCare plansInpatient medicineCareCancerPatientsAdultsSubspecialists
2019
Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures
Datta R, Wang T, Zhu M, Dembry LM, Han L, Allore H, Quagliarello V, Juthani-Mehta M. Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. Infection Control And Hospital Epidemiology 2019, 40: 470-472. PMID: 30821230, PMCID: PMC6482377, DOI: 10.1017/ice.2019.22.Peer-Reviewed Original ResearchConceptsUrinary tract infectionIncidence rate ratiosAdvanced cancer patientsAsymptomatic bacteriuriaCancer patientsAntimicrobial therapySymptomatic urinary tract infectionPotential urinary tract infectionTract infectionsInappropriate therapyAntimicrobial daysComfort measuresBacteriuriaCandiduriaCFU/mLPatientsTherapyRate ratioMLInfection
2016
Epidemiology of Clostridium difficile infection in hospitalized oncology patients
Chang GY, Dembry LM, Banach DB. Epidemiology of Clostridium difficile infection in hospitalized oncology patients. American Journal Of Infection Control 2016, 44: 1421-1423. PMID: 27287733, DOI: 10.1016/j.ajic.2016.04.210.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionBlood transfusionDifficile infectionHistory of CDIΒ-lactam/β-lactamase inhibitorsBroad-spectrum antibiotic useHospitalized oncology patientsRecent blood transfusionCDI historyCDI riskOlder patientsOncology inpatientsΒ-lactamase inhibitorsOncology patientsPrior receiptRisk factorsAntibiotic useMultivariate analysisTransfusionPatientsInfectionEpidemiologyInpatientsMetronidazoleCephalosporins
2013
Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial
Harris AD, Pineles L, Belton B, Johnson JK, Shardell M, Loeb M, Newhouse R, Dembry L, Braun B, Perencevich EN, Hall KK, Morgan DJ, Shahryar S, Price C, Gadbaw J, Drees M, Kett D, Muñoz-Price L, Jacob J, Herwaldt L, Sulis C, Yokoe D, Maragakis L, Lissauer M, Zervos M, Warren D, Carver R, Anderson D, Calfee D, Bowling J, Safdar N. Universal Glove and Gown Use and Acquisition of Antibiotic-Resistant Bacteria in the ICU: A Randomized Trial. JAMA 2013, 310: 1571-1580. PMID: 24097234, PMCID: PMC4026208, DOI: 10.1001/jama.2013.277815.Peer-Reviewed Original ResearchMeSH KeywordsAgedCross InfectionEnterococcusFemaleGloves, ProtectiveGram-Positive Bacterial InfectionsGuideline AdherenceHand DisinfectionHumansInfection ControlIntensive Care UnitsMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedPersonnel, HospitalStaphylococcal InfectionsSurgical AttireVancomycin ResistanceConceptsIntensive care unitMethicillin-resistant Staphylococcus aureusVancomycin-resistant EnterococcusIntervention ICUsSurgical intensive care unitPrimary outcomeHand hygiene complianceSecondary outcomesAdverse eventsPatient contactUniversal gloveVRE acquisitionUsual careMRSA acquisitionGown useHygiene complianceAcquisition of MRSAAntibiotic-resistant bacteriaControl intensive care unitHealth care-associated infectionsStudy periodKey secondary outcomesBaseline periodCare-associated infectionsHealth care workers
2007
Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections
Gupta K, MacIntyre A, Vanasse G, Dembry LM. Trends in Prescribing β-Lactam Antibiotics for Treatment of Community-Associated Methicillin-Resistant Staphylococcus aureus Infections. Journal Of Clinical Microbiology 2007, 45: 3930-3934. PMID: 17942648, PMCID: PMC2168566, DOI: 10.1128/jcm.01510-07.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBeta-LactamsChildChild, PreschoolCommunity-Acquired InfectionsDrug PrescriptionsFemaleHealth Services ResearchHumansInfantInfant, NewbornMaleMethicillin ResistanceMiddle AgedPrevalenceStaphylococcal InfectionsStaphylococcus aureusUnited StatesConceptsCA-MRSA soft tissue infectionsSoft tissue infectionsInitial empirical therapyCA-MRSA isolatesEmpirical therapyAntimicrobial therapyCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolatesStaphylococcal chromosomal cassette mec type IVS. aureus soft tissue infectionsResistant Staphylococcus aureus infectionsMethicillin-Resistant Staphylococcus aureus IsolatesInactive antimicrobial therapyRate of prescribingCA-MRSA infectionsInitial antimicrobial therapyMajority of patientsMedical record reviewSubset of patientsCommunity-Associated MethicillinStaphylococcus aureus infectionPanton-Valentine leukocidinStaphylococcus aureus isolatesBeta-lactam antibioticsDiscordant therapyRate of use
1999
A Decade of Prevalence Surveys in a Tertiary-Care Center: Trends in Nosocomial Infection Rates, Device Utilization, and Patient Acuity
Weinstein J, Mazon D, Pantelick E, Reagan-Cirincione P, Dembry L, Hierholzer W. A Decade of Prevalence Surveys in a Tertiary-Care Center: Trends in Nosocomial Infection Rates, Device Utilization, and Patient Acuity. Infection Control And Hospital Epidemiology 1999, 20: 543-548. PMID: 10466554, DOI: 10.1086/501675.Peer-Reviewed Original ResearchConceptsNosocomial infection ratesAcute care patientsNosocomial bloodstream infectionsPrevalence surveyNosocomial infectionsInfection rateBloodstream infectionsPotential quality improvement initiativesAbnormal laboratory indicatorsAnnual prevalence surveysInvasive device utilizationTertiary care centerAbnormal laboratory valuesSeverity of illnessAcute care bedsInfection control practitionersSurveillance System dataRate of infectionQuality improvement initiativesObstetric-gynecologic servicesCase mix indexChart reviewCare patientsFoley catheterLaboratory indicators
1998
Nosocomial Candida glabrata Colonization: an Epidemiologic Study
Vazquez J, Dembry L, Sanchez V, Vazquez M, Sobel J, Dmuchowski C, Zervos M. Nosocomial Candida glabrata Colonization: an Epidemiologic Study. Journal Of Clinical Microbiology 1998, 36: 421-426. PMID: 9466752, PMCID: PMC104553, DOI: 10.1128/jcm.36.2.421-426.1998.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone Marrow TransplantationCandidaCandidiasisChildChild, PreschoolCross InfectionDNA, FungalEnvironmental MicrobiologyFemaleHandHealth PersonnelHospitalizationHospitals, UniversityHumansIntensive Care UnitsMaleMiddle AgedMolecular EpidemiologyPolymorphism, Restriction Fragment LengthProspective StudiesRisk FactorsConceptsNosocomial acquisitionC. glabrataMedical intensive care unitBone marrow transplant unitPrior antimicrobial useDuration of hospitalizationIntensive care unitMarrow transplant unitSignificant risk factorsImportant nosocomial pathogenStrain typesSame strain typeCare unitTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatientsC. glabrata strainsEnvironmental surfacesHospital personnelNosocomial pathogenAntimicrobial useIdentical strainsHospital environment
1996
Control of endemic glycopeptide-resistant enterococci.
Dembry LM, Uzokwe K, Zervos MJ. Control of endemic glycopeptide-resistant enterococci. Infection Control And Hospital Epidemiology 1996, 17: 286-92. PMID: 8727617, DOI: 10.1086/647297.Peer-Reviewed Original ResearchConceptsVancomycin-resistant EnterococcusRenal unitsEradication of carriageVRE stool colonizationCommunity teaching hospitalPatient carriageBarrier precautionsOral doxycyclineFurther patientsStool colonizationGlycopeptide-resistant enterococciCulture surveyTeaching hospitalPatientsStudy periodEnterococcus faeciumEnterococcus gallinarumCarriageRifampinDoxycyclineEnterococcusControl measuresDaysUseful measureHospital
1993
Nosocomial Acquisition of Candida albicans: An Epidemiologic Study
Vazquez J, Sanchez V, Dmuchowski C, Dembry L, Sobel J, Zervos M. Nosocomial Acquisition of Candida albicans: An Epidemiologic Study. The Journal Of Infectious Diseases 1993, 168: 195-201. PMID: 8515108, DOI: 10.1093/infdis/168.1.195.Peer-Reviewed Original ResearchConceptsNosocomial acquisitionMedical intensive care unitBone marrow transplant unitIntensive care unitMarrow transplant unitIndirect patient contactC. albicansPrior antibioticsCare unitProspective studyTransplant unitUniversity HospitalRisk factorsEpidemiologic studiesPatient contactPatientsEnvironmental surfacesHospital personnelCandida albicansIdentical strainsStrain typesAdmissionLength of timeRestriction enzyme analysisAlbicansNosocomial acquisition of Candida parapsilosis: An epidemiologic study
Sanchez V, Vazquez J, Barth-Jones D, Dembry L, Sobel J, Zervos M. Nosocomial acquisition of Candida parapsilosis: An epidemiologic study. The American Journal Of Medicine 1993, 94: 577-582. PMID: 8389525, DOI: 10.1016/0002-9343(93)90207-6.Peer-Reviewed Original ResearchConceptsIntensive care unitC. parapsilosisMedicine intensive care unitBone marrow transplant unitNegative initial culturesTertiary care hospitalMarrow transplant unitLittle epidemiologic informationHands of personnelImportant nosocomial pathogenStrain typesRestriction enzyme analysisCandida parapsilosisEnvironmental surfacesImmunosuppressive therapyNosocomial acquisitionAntibiotic therapyCare hospitalCare unitTransplant unitControl subjectsHand culturesNosocomial infectionsPatient strainsEpidemiologic information
1992
Epidemiology of nosocomial acquisition of Candida lusitaniae
Sanchez V, Vazquez J, Barth-Jones D, Dembry L, Sobel J, Zervos M. Epidemiology of nosocomial acquisition of Candida lusitaniae. Journal Of Clinical Microbiology 1992, 30: 3005-3008. PMID: 1360476, PMCID: PMC270571, DOI: 10.1128/jcm.30.11.3005-3008.1992.Peer-Reviewed Original ResearchConceptsAmphotericin B.Medical intensive care unitC. lusitaniaeTertiary care hospitalIntensive care unitBone marrow transplantIndirect contact transmissionCandida lusitaniaeImportant nosocomial pathogenDuration of stayCatheter useImmunosuppressive therapyNosocomial acquisitionControl patientsAntibiotic administrationCare unitMarrow transplantAntifungal therapyExogenous acquisitionPatientsContact transmissionNosocomial pathogenIdentical strainsCandida speciesStrain types