2017
Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial
Buxbaum JL, Hormozdi D, Dinis-Ribeiro M, Lane C, Dias-Silva D, Sahakian A, Jayaram P, Pimentel-Nunes P, Shue D, Pepper M, Cho D, Laine L. Narrow-band imaging versus white light versus mapping biopsy for gastric intestinal metaplasia: a prospective blinded trial. Gastrointestinal Endoscopy 2017, 86: 857-865. PMID: 28366441, DOI: 10.1016/j.gie.2017.03.1528.Peer-Reviewed Original ResearchConceptsGastric intestinal metaplasiaDetection of GIMNarrow-band imagingHD-WLMapping biopsyIntestinal metaplasiaHigh-definition white light endoscopyProportion of patientsProspective blinded trialGastric cancer precursorsGastric cancer riskWhite light endoscopyNBI examinationPrimary outcomeUpper endoscopyHigher proportionBlinded trialCancer precursorsBiopsy specimensMedian numberSecond endoscopistGastric cancerCancer riskBiopsyPatients
2014
Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease
Kim JJ, Lee JS, Olafsson S, Laine L. Low Adherence to Helicobacter pylori Testing in Hospitalized Patients with Bleeding Peptic Ulcer Disease. Helicobacter 2014, 19: 98-104. PMID: 24617668, DOI: 10.1111/hel.12114.Peer-Reviewed Original ResearchConceptsH. pylori testingProportion of patientsIndex hospitalizationHospitalized patientsConsecutive hospitalized patientsPeptic ulcer diseaseHelicobacter pylori testingInitial endoscopyUlcer diseaseSerologic testingSingle centerEndoscopy databaseSociety guidelinesGastric ulcerLow adherencePatientsUlcersMultivariate analysisHelicobacter pyloriHospitalizationDirect testingBiopsyTestingEndoscopyPylori
1998
Effect of blood on rapid urease testing of gastric mucosal biopsy specimens
Laine L, Sidhom O, Emami S, Estrada R, Cohen H. Effect of blood on rapid urease testing of gastric mucosal biopsy specimens. Gastrointestinal Endoscopy 1998, 47: 141-143. PMID: 9512278, DOI: 10.1016/s0016-5107(98)70346-3.Peer-Reviewed Original ResearchConceptsRapid urease testBiopsy specimensUrease testEffect of bloodRapid urease test resultsGastric mucosal biopsy specimensMucosal biopsy specimensRapid urease testingGastric biopsy specimensUrease test resultsGastric bodyUrease testingPositive testDiscordant resultsBloodCLOtestPyloriTekHoursPatientsAntrumBiopsyMucosaEndoscopy
1996
The influence of size or number of biopsies on rapid urease test results: a prospective evaluation
Laine L, Chun D, Stein C, El-Beblawi I, Sharma V, Chandrasoma P. The influence of size or number of biopsies on rapid urease test results: a prospective evaluation. Gastrointestinal Endoscopy 1996, 43: 49-53. PMID: 8903818, DOI: 10.1016/s0016-5107(96)70260-2.Peer-Reviewed Original ResearchConceptsRegular biopsiesPositive testJumbo biopsyForceps biopsyAmount of tissueRapid urease test resultsHelicobacter pylori infectionNumber of biopsiesRapid urease testingUrease test resultsValuable diagnostic toolEndoscopic biopsyProspective evaluationPylori infectionUrease testingDiagnostic yieldHistologic examinationUrease testBiopsyRapid ureasePatientsFalse negative rateDiagnostic testsInterobserver agreementMean time
1989
Campylobacter pylori in alcoholic hemorrhagic “gastritis”
Laine L, Marin-Sorensen M, Weinstein W. Campylobacter pylori in alcoholic hemorrhagic “gastritis”. Digestive Diseases And Sciences 1989, 34: 677-680. PMID: 2785447, DOI: 10.1007/bf01540337.Peer-Reviewed Original ResearchConceptsSubepithelial hemorrhageCampylobacter pyloriInflammatory cell scoresInflammatory cell densityMucosal hemorrhageEdema scoreAlcoholic patientsHistologic abnormalitiesMononuclear cellsBiopsy specimensEpithelial abnormalitiesHemorrhagic lesionsNeutrophil scoreHemorrhage scoreHistologic scoringHemorrhageMucosaBiopsyBiopsy slidesMean scoreScoresPresence of CPPyloriAbnormalitiesCell density
1988
Prevalence ofCampylobacter pylori and association with antral mucosal histology in subjects with and without upper gastrointestinal symptoms
Pettross C, Appleman M, Cohen H, Valenzuela J, Chandrasoma P, Laine L. Prevalence ofCampylobacter pylori and association with antral mucosal histology in subjects with and without upper gastrointestinal symptoms. Digestive Diseases And Sciences 1988, 33: 649-653. PMID: 3371136, DOI: 10.1007/bf01540425.Peer-Reviewed Original ResearchConceptsUpper gastrointestinal symptomsGastrointestinal symptomsAsymptomatic volunteersNormal endoscopic findingsRoutine endoscopic evaluationPeptic ulcer diseaseYoung asymptomatic adultsAntral inflammationAntral gastritisEndoscopic findingsEndoscopic evaluationMucosal histologyUlcer diseaseAsymptomatic adultsChronic gastritisEndoscopic examinationHistological examinationPatientsVolunteersGastritisMucosaSymptomsExaminationAssociationBiopsy