Liming Hao, MD
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About
Biography
Dr. Hao completed her residency in Anatomic and Clinical Pathology at Yale New Haven Hospital. She also completed a fellowship in gastrointestinal pathology at Yale. She is part of the Yale Pathology faculty at Bridgeport Hospital.
Appointments
Pathology
Associate Clinical ProfessorPrimary
Other Departments & Organizations
- Pancreatic Diseases Program
- Pathology
- Pathology and Molecular Medicine
- Yale Ventures
Education & Training
- Fellow
- Yale -New Haven Hospital (2000)
- Resident
- Yale University School of Medicine (1999)
- Resident
- Yale-New Haven Hospital (1997)
- MD
- Beijing Medical University (1983)
- Fellow
- University of Colorado Health Sciences Center, Barbara Davis Center for Childhood Diabetes
Board Certifications
Anatomic & Clinical Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 2000
Research
Overview
The role of Immune regulation in the pathogenesis of Idiopathic Inflammatory
Bowel disease
Mechanism(s)of allograft rejection
Pathogenesis of Autoimmune diseases
Medical Research Interests
Allografts; Autoimmune Diseases; Inflammatory Bowel Diseases; Pathology
Research at a Glance
Yale Co-Authors
Frequent collaborators of Liming Hao's published research.
Publications Timeline
A big-picture view of Liming Hao's research output by year.
Joseph Madri, MD/PhD
Pei Hui, PhD, MD
Susan Bell
Young Choi, MD
8Publications
549Citations
Publications
2008
Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma
Choi YJ, M Pinto M, Hao L, K Riba A. Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma. Modern Pathology 2008, 21: 1224-1237. PMID: 18587329, DOI: 10.1038/modpathol.2008.106.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsE-cadherin stainingLobular carcinomaLobular neoplasiaDuct lesionsDuct carcinomaPrevious diagnosisBreast lesionsMorphologic diagnosisInterobserver variabilityDifferent antibodiesE-cadherinImportant therapeutic implicationsParaffin-embedded sectionsLoss of stainingE-cadherin staining patternDuctal neoplasiaDuctal lesionsHistologic featuresLobular lesionsHistology diagnosisSurgical pathologistsImmunohistochemistry techniquesTherapeutic implicationsBlinded mannerCarcinomaGenotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis
Bifulco C, Johnson C, Hao L, Kermalli H, Bell S, Hui P. Genotypic Analysis of Hydatidiform Mole: An Accurate and Practical Method of Diagnosis. The American Journal Of Surgical Pathology 2008, 32: 445-451. PMID: 18300805, DOI: 10.1097/pas.0b013e3181520034.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsMolar pregnancyMaternal endometrial tissuesDaily clinical practiceDNA ploidy analysisDNA genotypingCases of HMUnstained paraffin sectionsHistologic featuresEndometrial tissueMorphologic mimicsClinical practiceMolar gestationHydatidiform MoleParaffin sectionsChorionic villiDiagnosisRoutine diagnosisPregnancyPloidy analysisGenotypic analysisGenotypingPaternal originPCR amplification systemGestationCases
2006
Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis
Rakoff-Nahoum S, Hao L, Medzhitov R. Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis. Immunity 2006, 25: 319-329. PMID: 16879997, DOI: 10.1016/j.immuni.2006.06.010.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsInflammatory bowel diseaseToll-like receptorsAbsence of TLRDevelopment of IBDEtiology of IBDImmune systemIL-10-deficient miceImmune suppressive mechanismsInnate immune recognitionHost immune systemBowel diseaseIntestinal inflammationColitisCommensal microfloraImmune recognitionMiceMultiple mechanismsDisease susceptibilityDifferential rolesReceptorsInflammationInterleukinMicrofloraEtiologyDisease
2005
Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response
Peng T, Hao L, Madri JA, Su X, Elias JA, Stahl GL, Squinto S, Wang Y. Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response. Journal Of Clinical Investigation 2005, 115: 1590-1600. PMID: 15902311, PMCID: PMC1090470, DOI: 10.1172/jci22906.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAirway hyperresponsivenessAirway inflammationContribution of C5Airway responsesDevelopment of AHRHarmful inflammatory mediatorsRole of C5C5-deficient miceCourse of diseaseDownstream inflammatory cascadesInnate immune systemPotential clinical approachCritical checkpointAllergen provocationComplement component C5Inflammatory mediatorsInflammatory cascadeAirway lumenInflammatory cellsC5 inhibitionNonspecific stimuliClinical approachImmune systemInflammationC5b-9
2002
Murine model of gastrointestinal ischemia associated with complement-dependent injury
Zhao H, Montalto MC, Pfeiffer KJ, Hao L, Stahl GL. Murine model of gastrointestinal ischemia associated with complement-dependent injury. Journal Of Applied Physiology 2002, 93: 338-345. PMID: 12070223, DOI: 10.1152/japplphysiol.00159.2002.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAnimalsColoring AgentsComplement C5Complement System ProteinsDigestive SystemGastrointestinal DiseasesImmunohistochemistryIntercellular Adhesion Molecule-1IntestinesL-Lactate DehydrogenaseLungMaleMiceMice, Inbred C57BLMice, KnockoutPeroxidaseRegional Blood FlowReperfusion InjuryReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionConceptsRemote tissue injuryTissue injuryGastrointestinal ischemiaMurine modelComplement-mediated tissue injuryIntercellular adhesion molecule-1 mRNAAnti-C5 treatmentComplement-dependent injuryInflammatory protein-2 mRNAIschemia-reperfusion injuryAttenuates tissue injuryNew murine modelC5 monoclonal antibodyNeutrophil accumulationNeutrophil infiltrationNeutrophil recruitmentProtein-2 mRNAChemokine expressionActivate complementInjuryAdherence moleculesComplement activationMonoclonal antibodiesProtein expressionLactate dehydrogenase
1992
Facilitation of specific tolerance induction in adult mice by RS-61443.
Hao L, Calcinaro F, Gill RG, Eugui EM, Allison AC, Lafferty KJ. Facilitation of specific tolerance induction in adult mice by RS-61443. Transplantation 1992, 53: 590-5. PMID: 1549852.Peer-Reviewed Original Research
1990
Role of lymphokine in islet allograft rejection.
Hao LM, Wang Y, Gill RG, La Rosa FG, Talmage DW, Lafferty KJ. Role of lymphokine in islet allograft rejection. Transplantation 1990, 49: 609-14. PMID: 1969186.Peer-Reviewed Original Research
Others
- Kamanaka M, Kim ST, Hao L,and Flavell RA. A direct IL-10 signal to T cell is required to generate IL-10 producing T cells and to maintain the intestinal integrity. Manuscript submittedPeer-Reviewed Original Research