2018
CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris
Craiglow BG, Boyden LM, Hu R, Virtanen M, Su J, Rodriguez G, McCarthy C, Luna P, Larralde M, Humphrey S, Holland KE, Hogeling M, Hidalgo-Matlock B, Ferrari B, Fernandez-Faith E, Drolet B, Cordoro KM, Bowcock AM, Antaya RJ, Ashack K, Ashack RJ, Lifton RP, Milstone LM, Paller AS, Choate KA. CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris. Journal Of The American Academy Of Dermatology 2018, 79: 487-494. PMID: 29477734, PMCID: PMC6098739, DOI: 10.1016/j.jaad.2018.02.034.Peer-Reviewed Original ResearchConceptsPityriasis rubra pilarisPapulosquamous eruptionPsoriasis therapyFamily historyCARD14 mutationsRegistry of subjectsFeatures of psoriasisSystemic psoriasis therapiesSpectrum of diseaseDisorders of keratinizationWhole-exome sequencingOral retinoidsClinical characteristicsClinical featuresClinical historyTumor necrosisDiagnostic uncertaintyFamilial pityriasis rubra pilarisProminent involvementPsoriasisGenetic testingHeterozygous mutationsExome sequencingMinimal responseSmall sample size
2017
Establishing and Validating an Ichthyosis Severity Index
Marukian NV, Deng Y, Gan G, Ren I, Thermidor W, Craiglow BG, Milstone LM, Choate KA. Establishing and Validating an Ichthyosis Severity Index. Journal Of Investigative Dermatology 2017, 137: 1834-1841. PMID: 28596001, DOI: 10.1016/j.jid.2017.04.037.Peer-Reviewed Original ResearchConceptsIchthyosis severityDisorders of keratinizationIntrarater intraclass correlation coefficientsIntraclass correlation coefficientTherapeutic responseClinical trialsClinical phenotypingLevels of severityBody sitesErythemaSeverity IndexSeverityInterrater reliabilityPerson evaluationDermatologistsVisual indexSubjectsIndexVisual standardsSettingKeratinizationTrialsDifferent settings
1993
Secondary Hyperparathyroidism in Patients With Ichthyosis Is Not Caused by Vitamin D Deficiency or Ingestion of Retinoids
Milstone L, Bale S, Insogna K. Secondary Hyperparathyroidism in Patients With Ichthyosis Is Not Caused by Vitamin D Deficiency or Ingestion of Retinoids. JAMA Dermatology 1993, 129: 648-648. PMID: 8481031, DOI: 10.1001/archderm.1993.01680260120024.Peer-Reviewed Original ResearchConceptsSecondary hyperparathyroidismParathyroid hormoneVitamin DSerum PTH valuesVitamin D deficiencyDisorders of keratinizationNonbullous ichthyosiform erythrodermaD deficiencyPTH levelsPTH valuesClinical findingsBiopsy specimensPatientsDarier's diseaseIchthyosis vulgarisIchthyosiform erythrodermaPlasma samplesLamellar ichthyosisHyperparathyroidismEpidermolytic hyperkeratosisSeparate groupsDiseaseIchthyosisInheritance patternNew Haven
1992
The Effects of Isotretinoin on the Axial Skeleton and the Retinoid Effect-Reply
Milstone L, Insogna K. The Effects of Isotretinoin on the Axial Skeleton and the Retinoid Effect-Reply. JAMA Dermatology 1992, 128: 1650-1650. DOI: 10.1001/archderm.1992.04530010086018.Commentaries, Editorials and LettersSecondary hyperparathyroidismBone demineralizationEffect of isotretinoinDisorders of keratinizationRole of retinoidsExtraskeletal calcificationHypervitaminosis ACompression fracturesIndex patientsExperimental animalsLoss of calciumRetinoidsLong bonesHyperparathyroidismAxial skeletonPatientsIngestionBoneDemineralizationIsotretinoinOsteopeniaHumansLucencyCalcificationKeratinizationSerum Parathyroid Hormone Level Is Elevated in Some Patients With Disorders of Keratinization
Milstone LM, Ellison AF, Insogna KL. Serum Parathyroid Hormone Level Is Elevated in Some Patients With Disorders of Keratinization. JAMA Dermatology 1992, 128: 926-930. PMID: 1320849, DOI: 10.1001/archderm.1992.01680170058005.Peer-Reviewed Original ResearchConceptsDisorders of keratinizationPityriasis rubra pilarisPTH levelsSecondary hyperparathyroidismPTH valuesSerum parathyroid hormone levelsNormal PTH valuesParathyroid hormone valuesSerum PTH valuesParathyroid hormone levelsSerum PTH levelsElevated PTH levelsHigh calcium dietIchthyosis linearis circumflexaCongenital ichthyosiform erythrodermaSecond patientBullous congenital ichthyosiform erythrodermaExact prevalenceCalcium metabolismHormone valuesHormone levelsPatientsActive PTHPhysiologic significanceDifferent disorders
1986
Prescribing Retinoids: The Art and the Science
Milstone L. Prescribing Retinoids: The Art and the Science. JAMA Dermatology 1986, 122: 761-763. DOI: 10.1001/archderm.1986.01660190039011.Commentaries, Editorials and LettersDisorders of keratinizationNodulocystic acneFurther clinical experienceCourse of therapyAcneiform eruptionClinical efficacyGenitourinary tractEffective therapyChronic diseasesEpithelial tumorsEffective treatmentClinical experienceVersatile therapeutic agentsVitamin ASynthetic retinoidsAutosomal recessive ichthyosisTherapeutic agentsBeneficial effectsAcneRetinoidsBiochemical effectsRecessive ichthyosisIsotretinoinCareful observationTherapy