2009
Feasibility of NIRS in the Neurointensive Care Unit: A Pilot Study in Stroke Using Physiological Oscillations
Muehlschlegel S, Selb J, Patel M, Diamond S, Franceschini M, Sorensen A, Boas D, Schwamm L. Feasibility of NIRS in the Neurointensive Care Unit: A Pilot Study in Stroke Using Physiological Oscillations. Neurocritical Care 2009, 11: 288. PMID: 19649749, PMCID: PMC2782535, DOI: 10.1007/s12028-009-9254-4.Peer-Reviewed Original ResearchConceptsCare unitStroke patientsPhysiological oscillationsHemoglobin concentrationMicrovascular hemodynamicsPilot studyIschemic brain injuryNeurointensive care unitNeurocritical care unitPre-hospital settingRespiratory oscillationsWarrants further validationAbsolute hemoglobin concentrationResultsNine patientsCerebral perfusionHemispheric strokeBrain injuryHealthy controlsFuture clinical applicationsPatientsOwn controlClinical feasibilityBedside modalityContinuous-wave NIRSClinical application
2008
Low-pressure balloon angioplasty with adjuvant pharmacological therapy in patients with acute ischemic stroke caused by intracranial arterial occlusions
Nogueira R, Schwamm L, Buonanno F, Koroshetz W, Yoo A, Rabinov J, Pryor J, Hirsch J. Low-pressure balloon angioplasty with adjuvant pharmacological therapy in patients with acute ischemic stroke caused by intracranial arterial occlusions. Neuroradiology 2008, 50: 331-340. PMID: 18172631, DOI: 10.1007/s00234-007-0340-z.Peer-Reviewed Original ResearchConceptsRecanalization rateIntracranial arteriesLow-pressure balloon angioplastyGlycoprotein IIb-IIIa inhibitorsInternal carotid artery terminusT-PAAdjuvant pharmacological therapyIntravenous t-PAOverall recanalization rateAcute ischemic strokeIIb-IIIa inhibitorsIntracranial arterial occlusionProcedure-related morbidityHigher recanalization ratesChances of recanalizationIA urokinaseSymptomatic hemorrhageAcute strokeCerebral infarctionCoronary balloonIschemic strokeConsecutive patientsPharmacological therapyArterial occlusionMechanical thrombolysis