2012
Infarct Volume Is a Pivotal Biomarker After Intra-Arterial Stroke Therapy
Yoo A, Chaudhry Z, Nogueira R, Lev M, Schaefer P, Schwamm L, Hirsch J, González R. Infarct Volume Is a Pivotal Biomarker After Intra-Arterial Stroke Therapy. Stroke 2012, 43: 1323-1330. PMID: 22426317, DOI: 10.1161/strokeaha.111.639401.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overBiomarkersBrain InfarctionCohort StudiesDatabases, FactualFemaleFibrinolytic AgentsHumansInfusions, IntravenousMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingPredictive Value of TestsProspective StudiesRetrospective StudiesStrokeThrombolytic TherapyTissue Plasminogen ActivatorTomography, X-Ray ComputedTreatment OutcomeConceptsFinal infarct volumeIntra-arterial therapyAcute ischemic strokeInfarct volumeFunctional outcomeBetter outcomesIschemic strokePoor outcomeAnterior circulation acute ischemic strokeScale scoreHealth Stroke Scale scoreMedian admission National InstitutesMedian final infarct volumesLong-term functional outcomeIntra-arterial stroke therapyAdmission National InstitutesProximal artery occlusionStroke Scale scoreOnly independent predictorRankin Scale scoreArtery occlusionProspective cohortRankin ScaleIndependent predictorsClinical outcomes
2009
ABC/2 for rapid clinical estimate of infarct, perfusion, and mismatch volumes
Sims J, Gharai L, Schaefer P, Vangel M, Rosenthal E, Lev M, Schwamm L. ABC/2 for rapid clinical estimate of infarct, perfusion, and mismatch volumes. Neurology 2009, 72: 2104-2110. PMID: 19528517, PMCID: PMC2697964, DOI: 10.1212/wnl.0b013e3181aa5329.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBrainBrain InfarctionCerebral ArteriesCerebral HemorrhageCerebrovascular CirculationComputer SimulationDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedNerve Fibers, MyelinatedPredictive Value of TestsRetrospective StudiesSeverity of Illness IndexTime Factors
2004
ASPECTS on CTA Source Images Versus Unenhanced CT
Coutts S, Lev M, Eliasziw M, Roccatagliata L, Hill M, Schwamm L, Pexman J, Koroshetz W, Hudon M, Buchan A, Gonzalez R, Demchuk A. ASPECTS on CTA Source Images Versus Unenhanced CT. Stroke 2004, 35: 2472-2476. PMID: 15486327, DOI: 10.1161/01.str.0000145330.14928.2a.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain InfarctionCerebral AngiographyFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedConceptsAlberta Stroke Program Early CT ScoreCTA-SI Alberta Stroke Program Early CT ScoreCT angiography source imagesBaseline Alberta Stroke Program Early CT ScoreIschemic changesFavorable outcomeNCCT-Alberta Stroke Program Early CT ScoreAcute ischemic strokeFinal infarct sizeFinal infarct volumeFavorable patient outcomesNormal CT scanRate ratioCTA source imagesM2 occlusionsInfarct volumeIschemic strokeProximal occlusionSymptom onsetClinical outcomesMedian timeCT scoreInfarct sizePatient outcomesBaseline NCCT
2001
Frequency and Clinical Context of Decreased Apparent Diffusion Coefficient Reversal in the Human Brain
Grant P, He J, Halpern E, Wu O, Schaefer P, Schwamm L, Budzik R, Sorensen A, Koroshetz W, Gonzalez R. Frequency and Clinical Context of Decreased Apparent Diffusion Coefficient Reversal in the Human Brain. Radiology 2001, 221: 43-50. PMID: 11568319, DOI: 10.1148/radiol.2211001523.Peer-Reviewed Original ResearchConceptsImaging studiesClinical settingVenous sinus thrombosisMagnetic resonance imaging studyOnset of symptomsMR imaging findingsComplicated clinical settingsMR imaging studiesMR imaging examinationsResonance imaging studyGray matter regionsADC lesionsArterial infarctionPersistent symptomsSinus thrombosisClinical outcomesImaging findingsClinical historyImaging examinationsADC decreaseSame periodWhite matterGray matterMatter regionsT2 changes