2021
Association Between Hospital Volumes and Clinical Outcomes for Patients With Nontraumatic Subarachnoid Hemorrhage
Leifer D, Fonarow G, Hellkamp A, Baker D, Hoh B, Prabhakaran S, Schoeberl M, Suter R, Washington C, Williams S, Xian Y, Schwamm L. Association Between Hospital Volumes and Clinical Outcomes for Patients With Nontraumatic Subarachnoid Hemorrhage. Journal Of The American Heart Association 2021, 10: e018373. PMID: 34325522, PMCID: PMC8475679, DOI: 10.1161/jaha.120.018373.Peer-Reviewed Original ResearchConceptsAnnual case volumeComprehensive Stroke Center (CSC) certificationStroke center certificationNational Inpatient SampleSubarachnoid hemorrhageNontraumatic subarachnoid hemorrhageCase volumeHospital mortalityClinical outcomesPoor outcomeCenter certificationSAH casesBetter outcomesVolume thresholdHospital annual case volumeHospital case volumeCases/yearBackground Previous studiesLogistic regression modelsSAH hospitalizationsHospital volumeAneurysm obliterationInpatient SampleOdds ratioImproved outcomes
2015
Patient Characteristics and Outcomes After Hemorrhagic Stroke in Pregnancy
Leffert LR, Clancy CR, Bateman BT, Cox M, Schulte PJ, Smith EE, Fonarow GC, Schwamm LH, Kuklina EV, George MG. Patient Characteristics and Outcomes After Hemorrhagic Stroke in Pregnancy. Circulation Cardiovascular Quality And Outcomes 2015, 8: s170-s178. PMID: 26515206, DOI: 10.1161/circoutcomes.115.002242.Peer-Reviewed Original ResearchConceptsStroke risk factorsSubarachnoid hemorrhage patientsHemorrhagic strokeRisk factorsHS patientsHospital mortalityHemorrhage patientsDiseases-Ninth Revision codesBlood pressure criteriaGuidelines-Stroke registryPregnancy-related strokeAssociation of pregnancyNonpregnant female patientsConditional logistic regressionFisher's exact testWilcoxon rank sum testRank sum testGuidelines-StrokeSevere preeclampsiaHome dischargeIschemic strokeNonpregnant womenPatient characteristicsRisk patientsIndependent ambulation
2014
Hospital Case Volume Is Associated With Mortality in Patients Hospitalized With Subarachnoid Hemorrhage
Prabhakaran S, Fonarow G, Smith E, Liang L, Xian Y, Neely M, Peterson E, Schwamm L. Hospital Case Volume Is Associated With Mortality in Patients Hospitalized With Subarachnoid Hemorrhage. Neurosurgery 2014, 75: 500-508. PMID: 24979097, DOI: 10.1227/neu.0000000000000475.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleHospital MortalityHospitalsHumansLogistic ModelsMaleOdds RatioRegistriesSubarachnoid HemorrhageConceptsHospital case volumeHospital mortalitySubarachnoid hemorrhageCase volumeSAH volumeSAH patientsHospital characteristicsMedian annual case volumeGuidelines-Stroke registryLarge nationwide registryMultivariable logistic regressionLength of stayAnnual case volumeContemporary national dataIndependent ambulatory statusAmbulatory statusExperienced centersNationwide registryDischarge diagnosisOptimized careImproved outcomesRelevant patientsPatientsHospitalMortality
2013
A Risk Score for In‐Hospital Death in Patients Admitted With Ischemic or Hemorrhagic Stroke
Smith E, Shobha N, Dai D, Olson D, Reeves M, Saver J, Hernandez A, Peterson E, Fonarow G, Schwamm L. A Risk Score for In‐Hospital Death in Patients Admitted With Ischemic or Hemorrhagic Stroke. Journal Of The American Heart Association 2013, 2: e005207. PMID: 23525444, PMCID: PMC3603253, DOI: 10.1161/jaha.112.005207.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCerebral HemorrhageChi-Square DistributionDecision Support TechniquesFemaleHospital MortalityHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsRegistriesReproducibility of ResultsRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeSubarachnoid HemorrhageUnited StatesConceptsStroke typeIschemic strokeIntracerebral hemorrhageRisk scoreGuidelines-Stroke databaseHealth Stroke ScaleIn-Hospital DeathRisk of deathHospital mortalityHospital deathStroke ScaleStroke admissionsIndependent predictorsHemorrhagic strokeStroke patientsC-statisticSingle risk scoreOverall populationLogistic regressionPatientsValidation sampleMortalityDeathPoint scorePrediction score
2012
Peripartum Subarachnoid Hemorrhage
Bateman B, Olbrecht V, Berman M, Minehart R, Schwamm L, Leffert L. Peripartum Subarachnoid Hemorrhage. Anesthesiology 2012, 116: 324-333. PMID: 22166951, DOI: 10.1097/aln.0b013e3182410b22.Peer-Reviewed Original ResearchConceptsSubarachnoid hemorrhageHypertensive disordersRisk factorsPregnancy-related admissionsIndependent risk factorIntracranial venous thrombosisNationwide Inpatient SampleAfrican American raceVariety of etiologiesRange of etiologiesSickle cell diseaseIdentified admissionsHospital deathMaternal morbidityNonpregnant patientsNonpregnant womenIndependent predictorsMalignant etiologySevere headacheVenous thrombosisNonpregnant controlsPregnancy resultsVenous bleedingInstitution experienceInpatient Sample
2010
Characteristics, Performance Measures, and In-Hospital Outcomes of the First One Million Stroke and Transient Ischemic Attack Admissions in Get With The Guidelines-Stroke
Fonarow G, Reeves M, Smith E, Saver J, Zhao X, Olson D, Hernandez A, Peterson E, Schwamm L. Characteristics, Performance Measures, and In-Hospital Outcomes of the First One Million Stroke and Transient Ischemic Attack Admissions in Get With The Guidelines-Stroke. Circulation Cardiovascular Quality And Outcomes 2010, 3: 291-302. PMID: 20177051, DOI: 10.1161/circoutcomes.109.921858.Peer-Reviewed Original ResearchConceptsHospital mortality rateIntracerebral hemorrhageQuality of careIschemic strokeSubarachnoid hemorrhageMortality rateTransient ischemic attack admissionsTransient ischemic attack patientsIn-Hospital OutcomesAcute ischemic strokeIschemic stroke patientsAdjusted odds ratioLength of stayQuality improvement effortsGuidelines-StrokeGWTG-StrokeTIA admissionsTIA careTIA patientsHospital outcomesAcute strokeStroke patientsMean ageAttack patientsNational surveillance
2009
Influence of stroke subtype on quality of care in the Get With The Guidelines–Stroke Program
Smith E, Liang L, Hernandez A, Reeves M, Cannon C, Fonarow G, Schwamm L. Influence of stroke subtype on quality of care in the Get With The Guidelines–Stroke Program. Neurology 2009, 73: 709-716. PMID: 19720978, PMCID: PMC2734292, DOI: 10.1212/wnl.0b013e3181b59a6e.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCerebral HemorrhageEmergency Medical ServicesFemaleGuideline AdherenceHospitalsHumansMaleMiddle AgedOutcome Assessment, Health CarePractice Guidelines as TopicQuality Assurance, Health CareQuality of Health CareRisk Reduction BehaviorSmoking CessationStrokeSubarachnoid HemorrhageUnited StatesVenous ThrombosisConceptsQuality of careIS/TIAIntracerebral hemorrhageIschemic strokeStroke subtypesTIA admissionsHemorrhagic strokeCare measuresDeep venous thrombosis preventionHospital-based acute careGuidelines-Stroke databaseGuidelines-Stroke programGWTG-Stroke programVenous thrombosis preventionSmoking cessation therapyMeasures of careLogistic regression modelsDVT preventionIneligible patientsNational GetDysphagia screeningCessation therapySAH patientsAcute careICH patients
2001
Fever in subarachnoid hemorrhage
Oliveira–Filho J, Ezzeddine M, Segal A, Buonanno F, Chang Y, Ogilvy C, Rordorf G, Schwamm L, Koroshetz W, McDonald C. Fever in subarachnoid hemorrhage. Neurology 2001, 56: 1299-1304. PMID: 11376177, DOI: 10.1212/wnl.56.10.1299.Peer-Reviewed Original ResearchConceptsSubarachnoid hemorrhagePoor outcomeTranscranial DopplerNeurologic intensive care unitOlder ageDaily transcranial DopplerGlasgow Coma ScoreHunt-Hess gradeRankin Scale scoreCause of feverIntensive care unitPresence of infectionNontraumatic subarachnoid hemorrhageSymptomatic vasospasmCerebral ischemiaComa ScoreConsecutive patientsAngiographic criteriaCare unitBrain injuryHemorrhage severityVasospasmPatientsFeverScale score
1999
Diffusion- and Perfusion-Weighted Imaging in Vasospasm After Subarachnoid Hemorrhage
Rordorf G, Koroshetz W, Copen W, Gonzalez G, Yamada K, Schaefer P, Schwamm L, Ogilvy C, Sorensen A. Diffusion- and Perfusion-Weighted Imaging in Vasospasm After Subarachnoid Hemorrhage. Stroke 1999, 30: 599-605. PMID: 10066858, DOI: 10.1161/01.str.30.3.599.Peer-Reviewed Original ResearchMeSH KeywordsAdultDiffusionFemaleHumansIschemic Attack, TransientMagnetic Resonance ImagingMalePerfusionSubarachnoid HemorrhageConceptsRelative cerebral blood flowRelative cerebral blood volumeAngiographic vasospasmIschemic injurySymptomatic vasospasmNeurological deficitsClinical signsSevere angiographic vasospasmCerebral tissue perfusionEarly ischemic injurySubarachnoid hemorrhage patientsCerebral blood flowIntravenous contrast bolusPerfusion-Weighted ImagingCerebral blood volumeDWI abnormalitiesAsymptomatic patientsHemodynamic abnormalitiesNormal angiogramsAngiographic spasmImaging abnormalitiesIschemic lesionsHemorrhage patientsSubarachnoid hemorrhageClinical management
1998
Effects of Induced Hypertension on Transcranial Doppler Ultrasound Velocities in Patients After Subarachnoid Hemorrhage
Manno E, Gress D, Schwamm L, Diringer M, Ogilvy C. Effects of Induced Hypertension on Transcranial Doppler Ultrasound Velocities in Patients After Subarachnoid Hemorrhage. Stroke 1998, 29: 422-428. PMID: 9472884, DOI: 10.1161/01.str.29.2.422.Peer-Reviewed Original ResearchConceptsMiddle cerebral arteryInduced hypertensionTCD velocitiesSubarachnoid hemorrhageTranscranial Doppler ultrasoundIntact autoregulationArterial pressureCerebral vasospasmCerebral arteryCerebral autoregulationTranscranial Doppler ultrasound velocitiesCerebral blood flow velocityContinuous TCD monitoringMean arterial pressureBlood flow velocityLevel of autoregulationDoppler ultrasound velocitiesAdditional patientsClinical evidenceClinical differencesTCD monitoringHypertensionDoppler ultrasoundHemorrhagePatients