2018
Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial
Nogueira R, Frei D, Kirmani J, Zaidat O, Lopes D, Turk A, Heck D, Mason B, Haussen D, Levy E, Mehta S, Lazzaro M, Chen M, Dörfler A, Yoo A, Derdeyn C, Schwamm L, Langer D, Siddiqui A. Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial. JAMA Neurology 2018, 75: 304-311. PMID: 29296999, PMCID: PMC5885851, DOI: 10.1001/jamaneurol.2017.3967.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeSerious adverse eventsProcedure-related serious adverse eventsStent retrieverMechanical thrombectomy devicesAspiration groupAdverse eventsEnd pointClinical trialsThrombectomy devicesLarge vessel acute ischemic strokeDevice-related serious adverse eventsScale scoreHealth Stroke Scale scoreMedian baseline NIHSS scorePrimary effectiveness end pointPrimary safety end pointAcute ischemic stroke interventionCerebral infarction (TICI) gradeEffectiveness end pointBaseline NIHSS scorePrimary end pointSafety end pointStroke Scale scoreHours of onset
2015
Trends in Endovascular Therapy and Clinical Outcomes Within the Nationwide Get With The Guidelines-Stroke Registry
Menon B, Saver J, Goyal M, Nogueira R, Prabhakaran S, Liang L, Xian Y, Hernandez A, Fonarow G, Schwamm L, Smith E. Trends in Endovascular Therapy and Clinical Outcomes Within the Nationwide Get With The Guidelines-Stroke Registry. Stroke 2015, 46: 989-995. PMID: 25681065, DOI: 10.1161/strokeaha.114.007542.Peer-Reviewed Original ResearchConceptsSymptomatic intracerebral hemorrhageEndovascular therapyClinical outcomesPatient characteristicsIntracerebral hemorrhageBaseline National InstitutesEndovascular therapy useGuidelines-Stroke hospitalsGuidelines-Stroke registryHealth Stroke ScaleAcute ischemic strokeProportion of hospitalsNew thrombectomy deviceHospital mortalityStroke ScaleIschemic strokeIndependent ambulationNumber of hospitalsTherapy useMultivariable analysisPatient outcomesThrombectomy devicesHospitalTherapyStudy period