2023
Variation in patterns of telestroke usage during the COVID-19 pandemic
Nakamoto C, Wilcock A, Schwamm L, Zachrison K, Uscher-Pines L, Mehrotra A. Variation in patterns of telestroke usage during the COVID-19 pandemic. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107036. PMID: 36791674, PMCID: PMC9899774, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107036.Peer-Reviewed Original Research
2021
Association of Hospital Telestroke Adoption With Changes in Initial Hospital Presentation and Transfers Among Patients With Stroke and Transient Ischemic Attacks
Zachrison K, Richard J, Wilcock A, Zubizaretta J, Schwamm L, Uscher-Pines L, Mehrotra A. Association of Hospital Telestroke Adoption With Changes in Initial Hospital Presentation and Transfers Among Patients With Stroke and Transient Ischemic Attacks. JAMA Network Open 2021, 4: e2126612. PMID: 34554236, PMCID: PMC8461501, DOI: 10.1001/jamanetworkopen.2021.26612.Peer-Reviewed Original ResearchConceptsHospital stroke volumeControl hospitalsStroke volumeStroke centersStroke symptomsStroke systemsCase mixTransient ischemic attack admissionsHospital pairsInitial hospital presentationThrombectomy-capable hospitalsComprehensive stroke centerTransient ischemic attackPrimary stroke centerCross-sectional studyMajor teaching hospitalObserved patient characteristicsBed sizeHospital presentationIschemic attackInitial hospitalCritical access hospitalsPatient characteristicsInterhospital transferPostimplementation period
2019
Hospital Factors Associated With Interhospital Transfer Destination for Stroke in the Northeast United States
Zachrison K, Onnela J, Reeves M, Hernandez A, Camargo C, Zhao X, Matsouaka R, Goldstein J, Metlay J, Schwamm L. Hospital Factors Associated With Interhospital Transfer Destination for Stroke in the Northeast United States. Journal Of The American Heart Association 2019, 9: e011575. PMID: 31888430, PMCID: PMC6988147, DOI: 10.1161/jaha.118.011575.Peer-Reviewed Original ResearchMeSH KeywordsCatchment Area, HealthDatabases, FactualDelivery of Health Care, IntegratedFibrinolytic AgentsHospitalsHospitals, High-VolumeHospitals, Low-VolumeHumansMedicarePatient TransferPractice Patterns, Physicians'Quality Indicators, Health CareRetrospective StudiesStrokeThrombolytic TherapyTissue Plasminogen ActivatorUnited StatesConceptsAcute ischemic strokeAlteplase administrationIschemic strokeUS hospitalsHospital qualityHospital stroke volumeTransfer destinationsHospital referral regionsHospital factorsNumber of hospitalsStroke patientsHospital characteristicsStroke volumeMedicare claimsReferral regionsHospitalLogistic regressionStrokePatientsHospital performancePotential strategyAdministrationHome timeResult dataConnected dyads
2016
Hospital Variation in Home-Time After Acute Ischemic Stroke
O'Brien E, Xian Y, Xu H, Wu J, Saver J, Smith E, Schwamm L, Peterson E, Reeves M, Bhatt D, Maisch L, Hannah D, Lindholm B, Olson D, Prvu Bettger J, Pencina M, Hernandez A, Fonarow G. Hospital Variation in Home-Time After Acute Ischemic Stroke. Stroke 2016, 47: 2627-2633. PMID: 27625383, DOI: 10.1161/strokeaha.116.013563.Peer-Reviewed Original ResearchConceptsIschemic strokeStroke survivorsStroke volumeAdmission volumePost dischargeAcute ischemic strokeIschemic stroke survivorsHighest priority outcomesMore comorbiditiesRegistry patientsSevere strokeHospital factorsAdjusted analysisHospital variationHospital characteristicsPost strokeMedicare claimsRural locationsHospitalStrokePatientsRisk adjustmentLinear mixed modelsFirst yearSurvivors
2012
Data quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit
Xian Y, Fonarow G, Reeves M, Webb L, Blevins J, Demyanenko V, Zhao X, Olson D, Hernandez A, Peterson E, Schwamm L, Smith E. Data quality in the American Heart Association Get With The Guidelines-Stroke (GWTG-Stroke): Results from a National Data Validation Audit. American Heart Journal 2012, 163: 392-398.e1. PMID: 22424009, DOI: 10.1016/j.ahj.2011.12.012.Peer-Reviewed Original ResearchConceptsMedical recordsDeep venous thrombosis prophylaxisPrimary stroke center certificationGWTG-Stroke hospitalsHospital academic statusStroke center certificationVenous thrombosis prophylaxisNational Stroke RegistryAmerican Heart AssociationQuality Improvement ProgramIntraclass correlationIschemic stroke volumeGuidelines-StrokeGWTG-StrokeStroke RegistryThrombosis prophylaxisNeedle timeSerum creatinineSymptom onsetHeart AssociationCenter certificationStroke volumeRegistry dataRegistry participationCategorical variables
1998
Increased plasma levels of lipid hydroperoxides in patients with ischemic stroke
Polidori M, Frei B, Cherubini A, Nelles G, Rordorf G, Keaney J, Schwamm L, Mecocci P, Koroshetz W, Beal M. Increased plasma levels of lipid hydroperoxides in patients with ischemic stroke. Free Radical Biology And Medicine 1998, 25: 561-567. PMID: 9741593, DOI: 10.1016/s0891-5849(98)00085-9.Peer-Reviewed Original ResearchConceptsIschemic brain injuryCerebral syndromeCortical strokePlasma levelsBrain injuryOxidative stressGlasgow Coma ScaleNIH Stroke ScaleLipid hydroperoxidesStroke ScaleIschemic strokeComa ScaleLacunar infarctsStroke volumeMRI scansPatientsTherapeutic interventionsDay 5Significant negative correlationSignificant positive correlationSyndromeStrokeAscorbic acid concentrationInjuryPositive correlation