2019
The Mild and Rapidly Improving Stroke Study (MaRISS): Rationale and design
Romano J, Gardener H, Campo-Bustillo I, Khan Y, Riley N, Tai S, Sacco R, Khatri P, Smith E, Schwamm L. The Mild and Rapidly Improving Stroke Study (MaRISS): Rationale and design. International Journal Of Stroke 2019, 14: 983-986. PMID: 31496438, DOI: 10.1177/1747493019873595.Peer-Reviewed Original ResearchConceptsStroke symptomsStroke Impact Scale-16Actual treatment ratesMild ischemic strokePrimary safety outcomeSymptomatic hemorrhagic transformationProportion of patientsThird of patientsProspective observational studyEffect of alteplaseAcute stroke trialsLong-term outcomesPredictors of outcomeAlteplase treatmentHemorrhagic transformationIschemic strokeRankin ScaleSecondary outcomesBarthel IndexPrimary outcomeResidual disabilityStroke presentationRetrospective studyStroke StudyStroke trials
2016
Distinct Short-Term Outcomes in Patients With Mild Versus Rapidly Improving Stroke Not Treated With Thrombolytics
Romano J, Smith E, Liang L, Gardener H, Campo-Bustillo I, Khatri P, Bhatt D, Fonarow G, Sacco R, Schwamm L. Distinct Short-Term Outcomes in Patients With Mild Versus Rapidly Improving Stroke Not Treated With Thrombolytics. Stroke 2016, 47: 1278-1285. PMID: 26987870, DOI: 10.1161/strokeaha.115.011528.Peer-Reviewed Original ResearchConceptsHealth Stroke ScaleShort-term outcomesMild strokeHome dischargeIndependent ambulationStroke ScaleHealth Stroke Scale 0National InstituteGuidelines-Stroke registryVascular risk factorsLength of stayHospital mortalityHospital deathIschemic strokeSymptom onsetDischarge outcomesStroke presentationStroke symptomsHospital covariatesAdjusted outcomesRisk factorsWorse outcomesMultivariable modelRetrospective analysisGreater severityTelestroke—the promise and the challenge. Part two—expansion and horizons
Akbik F, Hirsch J, Chandra R, Frei D, Patel A, Rabinov J, Rost N, Schwamm L, Leslie-Mazwi T. Telestroke—the promise and the challenge. Part two—expansion and horizons. Journal Of NeuroInterventional Surgery 2016, 9: 361. PMID: 26984867, DOI: 10.1136/neurintsurg-2016-012340.Peer-Reviewed Original ResearchConceptsSpecialist careMajor public health concernAcute ischemic strokeTime-sensitive therapiesExamination of patientsUse of telemedicinePublic health concernNovel therapeutic platformIntravenous thrombolysisStroke preventionEndovascular thrombectomyIschemic strokeStroke presentationStroke expertiseTreatment benefitVideo consultationsTreatment ratesHealth concernTelestrokeCarePotential roleStrokeSensitive therapyTherapeutic platformThrombectomyTelestroke—the promise and the challenge. Part one: growth and current practice
Akbik F, Hirsch J, Chandra R, Frei D, Patel A, Rabinov J, Rost N, Schwamm L, Leslie-Mazwi T. Telestroke—the promise and the challenge. Part one: growth and current practice. Journal Of NeuroInterventional Surgery 2016, 9: 357. PMID: 26984868, DOI: 10.1136/neurintsurg-2016-012291.Peer-Reviewed Original ResearchConceptsSpecialist careMajor public health concernAcute ischemic strokeLarge vessel occlusionManagement of patientsTime-sensitive therapiesExamination of patientsUse of telemedicinePublic health concernIntravenous thrombolysisEndovascular thrombectomyIschemic strokeStroke presentationStroke expertiseVessel occlusionTreatment benefitVideo consultationsTreatment ratesHealth concernTelestrokeCurrent practicePatientsStrokeSensitive therapyCare
2012
Standardizing the Structure of Stroke Clinical and Epidemiologic Research Data
Saver J, Warach S, Janis S, Odenkirchen J, Becker K, Benavente O, Broderick J, Dromerick A, Duncan P, Elkind M, Johnston K, Kidwell C, Meschia J, Schwamm L. Standardizing the Structure of Stroke Clinical and Epidemiologic Research Data. Stroke 2012, 43: 967-973. PMID: 22308239, PMCID: PMC3493110, DOI: 10.1161/strokeaha.111.634352.Peer-Reviewed Original ResearchConceptsCommon data elementsNeurological disordersStroke Common Data ElementsLong-term therapyClinical practice guidelinesNational InstituteCase report formsPrior health statusPatient-oriented researchAcute therapyHospital courseStroke presentationCerebrovascular diseaseMedical historyNational registryClinical trialsStroke typePractice guidelinesHealth statusEnd pointVital signsClinical researchReport formsData elementsTherapy