2023
SMS-text messaging for collecting outcome measures after acute stroke
DiCarlo J, Erler K, Petrilli M, Emerson K, Gochyyev P, Schwamm L, Lin D. SMS-text messaging for collecting outcome measures after acute stroke. Frontiers In Digital Health 2023, 5: 1043806. PMID: 36910572, PMCID: PMC9996089, DOI: 10.3389/fdgth.2023.1043806.Peer-Reviewed Original ResearchModified Rankin ScaleAcute strokeOutcomes Measurement Information System (PROMIS) Global-10Acute stroke treatmentText messaging programsNIH Stroke ScaleOutcome data collectionHospitalization dischargeSMS text messagingHospital stayStroke ScaleMRS scoreRankin ScaleStroke treatmentFunctional outcomePROM scoresOutcome measuresWeighted Cohen's kappaPatientsSignificant associationStrokeTraditional followSMS textOutcomesParticipant satisfaction
2022
Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe
Hyle E, Foote J, Shebl F, Qian Y, Reddy K, Mukerji S, Wattananimitgul N, Viswanathan A, Schwamm L, Pandya A, Freedberg K. Development and validation of the age-associated dementia policy (AgeD-Pol) computer simulation model in the USA and Europe. BMJ Open 2022, 12: e056546. PMID: 35793913, PMCID: PMC9260808, DOI: 10.1136/bmjopen-2021-056546.Peer-Reviewed Original ResearchConceptsAge-associated dementiaKaiser Permanente Northern CaliforniaCumulative incidenceAAD incidenceInternal validationLifetime cumulative incidenceSex-stratified dataExternal validationFramingham Heart StudyCohort studyRotterdam StudyRotterdam cohortDisease burdenDisease progressionOutcome measuresHeart StudyDATA SOURCESACT cohortAdult ChangesCohort dataNatural historyCohortMortalityHealth systemIncidenceAssociation of Modified Rankin Scale With Recovery Phenotypes in Patients With Upper Extremity Weakness After Stroke
Erler K, Wu R, DiCarlo J, Petrilli M, Gochyyev P, Hochberg L, Kautz S, Schwamm L, Cramer S, Finklestein S, Lin D. Association of Modified Rankin Scale With Recovery Phenotypes in Patients With Upper Extremity Weakness After Stroke. Neurology 2022, 98: e1877-e1885. PMID: 35277444, PMCID: PMC9109148, DOI: 10.1212/wnl.0000000000200154.Peer-Reviewed Original ResearchConceptsModified Rankin ScaleUpper extremity weaknessMRS scoreStroke trialsFunctional outcomeOutcome measuresMRS levelsExtremity weaknessRankin ScaleMRS outcomesMotor impairmentFuture stroke trialsDaily living statusUpper extremity impairmentMeaningful changeGlobal outcome measuresMeaningful clinical changeIschemic strokeFugl-MeyerGrip strengthMotor phenotypeClinical changesClinical careDaily livingPatients
2021
Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors
Etherton M, Shah S, Haolin X, Xian Y, Maisch L, Hannah D, Lindholm B, Lytle B, Thomas L, Smith E, Fonarow G, Schwamm L, Bhatt D, Hernandez A, O'Brien E. Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors. Stroke And Vascular Neurology 2021, 6: 384-394. PMID: 33526632, PMCID: PMC8485250, DOI: 10.1136/svn-2020-000691.Peer-Reviewed Original ResearchConceptsAntidepressant medicationIschemic strokeCause mortalityClinical outcomesOutcome measuresAD useHealth Stroke Scale scoreHigher admission National InstitutesMajor adverse cardiac eventsAdmission National InstitutesGuidelines-Stroke hospitalsPrior ischemic strokeAdverse cardiac eventsIschemic stroke survivorsStroke Scale scorePoor prognostic signPoor clinical outcomeLogistic regression modelsFalsification endpointsAntidepressant therapyCause readmissionNaïve patientsCardiac eventsPoststroke depressionStroke severity
2020
Patient reported outcome measures (PROMs) in amyotrophic lateral sclerosis
De Marchi F, Berry J, Chan J, Caldwell S, Ellrodt A, Scalia J, Burke K, Fang T, Clark Sisodia R, Schwamm L, Moura L, Paganoni S. Patient reported outcome measures (PROMs) in amyotrophic lateral sclerosis. Journal Of Neurology 2020, 267: 1754-1759. PMID: 32125520, DOI: 10.1007/s00415-020-09774-8.Peer-Reviewed Original ResearchConceptsOutcome measuresClinical careALS Functional RatingMental health subscoresALSFRS-R scoreOutpatient clinic visitsOutcomes Measurement Information SystemClinical outcome measuresRoutine clinical careMental health scoresAmyotrophic lateral sclerosisMeasurement Information SystemQuality of lifeTablet-based surveyALS careALS clinicClinic visitsPROM scoresFunctional ratingClinic staffHealth scoresLateral sclerosisPROM collectionPatientsPhysical health
2016
Feasibility of the collection of patient-reported outcomes in an ambulatory neurology clinic
Moura L, Schwamm E, Moura Junior V, Seitz M, Hsu J, Cole A, Schwamm L. Feasibility of the collection of patient-reported outcomes in an ambulatory neurology clinic. Neurology 2016, 87: 2435-2442. PMID: 27815405, PMCID: PMC5177682, DOI: 10.1212/wnl.0000000000003409.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresT-scoreNeurology clinicAmbulatory neurology clinicMental health T-scoresGeneral neurology clinicPatient-reported outcomesMental health scoresUS general populationQuality of lifeMental health assessmentMean T-scoreQOLIE-10Rankin ScaleNeurology patientsEpilepsy scoresClinical dataOutcome measuresHealth scoresAdministrative claimsGeneral populationPatientsStudy periodVulnerable populationsDemographic characteristicsAssessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries
Fonarow G, Liang L, Thomas L, Xian Y, Saver J, Smith E, Schwamm L, Peterson E, Hernandez A, Duncan P, O'Brien E, Bushnell C, Prvu Bettger J. Assessment of Home-Time After Acute Ischemic Stroke in Medicare Beneficiaries. Stroke 2016, 47: 836-842. PMID: 26892279, DOI: 10.1161/strokeaha.115.011599.Peer-Reviewed Original ResearchConceptsModified Rankin ScaleIschemic strokeMedicare beneficiariesIschemic stroke Longitudinal (AVAIL) registryMedian Modified Rankin ScaleAcute ischemic strokePatient-centered outcomesSkilled nursing facilitiesGuidelines-StrokeMRS 0Older patientsRankin ScaleStroke careInpatient rehabilitationStroke survivorsC-indexOutcome measuresNursing facilitiesFunctional independenceAdherence evaluationStrokePatientsSimilar findingsMeaningful outcomesPearson correlation coefficient
2015
An International Standard Set of Patient-Centered Outcome Measures After Stroke
Salinas J, Sprinkhuizen S, Ackerson T, Bernhardt J, Davie C, George M, Gething S, Kelly A, Lindsay P, Liu L, Martins S, Morgan L, Norrving B, Ribbers G, Silver F, Smith E, Williams L, Schwamm L. An International Standard Set of Patient-Centered Outcome Measures After Stroke. Stroke 2015, 47: 180-186. PMID: 26604251, PMCID: PMC4689178, DOI: 10.1161/strokeaha.115.010898.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesOutcome measuresInternational standard setTransient ischemic attackHealth-related qualityCare-related factorsStroke Outcome MeasureSystemic risk factorsDifferent care settingsPreferred outcome measureRisk-adjustment variablesValue-based health careInternational expert panelIschemic attackAcute complicationsIschemic strokePatient demographicsStroke outcomeStroke RegisterIntracerebral hemorrhageStroke careStroke managementRisk factorsStroke typeCare settingsLack of Impact of Electronic Health Records on Quality of Care and Outcomes for Ischemic Stroke
Joynt K, Bhatt D, Schwamm L, Xian Y, Heidenreich P, Fonarow G, Smith E, Neely M, Grau-Sepulveda M, Hernandez A. Lack of Impact of Electronic Health Records on Quality of Care and Outcomes for Ischemic Stroke. Journal Of The American College Of Cardiology 2015, 65: 1964-1972. PMID: 25953748, DOI: 10.1016/j.jacc.2015.02.059.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overElectronic Health RecordsFemaleHospital Bed CapacityHospital MortalityHospitals, TeachingHumansLength of StayMaleMiddle AgedOutcome Assessment, Health CarePatient DischargePractice Guidelines as TopicQuality of Health CareStrokeTime-to-TreatmentTissue Plasminogen ActivatorUnited StatesConceptsElectronic health recordsIschemic strokeGWTG-Stroke hospitalsHealth recordsBetter clinical outcomesLogistic regression analysisAmerican Hospital Association Annual SurveyQuality of careOutcomes of interestHigh-quality careGuidelines-StrokeHospital mortalityStroke centersClinical outcomesStroke careSimilar oddsHospital characteristicsOutcome measuresTimely careHospitalPatientsStudy periodCareU.S. hospitalsStroke
2014
Stroke Outcomes Measures Must Be Appropriately Risk Adjusted to Ensure Quality Care of Patients
Fonarow G, Alberts M, Broderick J, Jauch E, Kleindorfer D, Saver J, Solis P, Suter R, Schwamm L. Stroke Outcomes Measures Must Be Appropriately Risk Adjusted to Ensure Quality Care of Patients. Stroke 2014, 45: 1589-1601. PMID: 24523036, DOI: 10.1161/str.0000000000000014.Peer-Reviewed Original ResearchConceptsAmerican Heart Association/American Stroke AssociationAmerican Stroke AssociationStroke Outcome MeasureOutcome measuresAdequate risk adjustmentIschemic strokeStroke patientsStroke AssociationAcute ischemic stroke patientsMedicaid ServicesRisk adjustmentHealth Stroke ScaleHospital-level outcomesAcute ischemic strokeIschemic stroke patientsEvidence-based careCause of deathStroke severity measuresRisk-adjusted outcome measuresStroke ScaleStroke careStroke mortalityReadmission measuresPatientsCase mix
2008
Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack
Schwamm L, Fonarow G, Reeves M, Pan W, Frankel M, Smith E, Ellrodt G, Cannon C, Liang L, Peterson E, LaBresh K. Get With the Guidelines–Stroke Is Associated With Sustained Improvement in Care for Patients Hospitalized With Acute Stroke or Transient Ischemic Attack. Circulation 2008, 119: 107-115. PMID: 19075103, DOI: 10.1161/circulationaha.108.783688.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAcute DiseaseAgedAged, 80 and overEvidence-Based MedicineFemaleGuideline AdherenceHospitalizationHospitals, CommunityHumansIschemic Attack, TransientLogistic ModelsMaleMiddle AgedMultivariate AnalysisProspective StudiesQuality of Health CareRisk FactorsStrokeThrombolytic TherapyConceptsTransient ischemic attackGuidelines-StrokeIschemic attackDeep vein thrombosis prophylaxisNational quality improvement programStroke performance measuresTreatment of strokeEvidence-based guidelinesMain outcome measuresLow-density lipoproteinQuality Improvement ProgramComposite measureDischarge antithromboticsEarly antithromboticsThrombosis prophylaxisIntravenous thrombolyticsAcute strokeIschemic strokeGuideline recommendationsStroke careAtrial fibrillationLipid treatmentCommunity hospitalOutcome measuresSustained improvement