2022
Rationale and design of a stepped wedge cluster randomised trial to improve acute reperfusion treatment quality for stroke: IMPROVE stroke care in China
Li Z, Wang C, Zhang X, Zong L, Zhou H, Gu H, Jiang Y, Pan Y, Meng X, Zhou Q, Zhao H, Yang X, Wang M, Xiong Y, Zhao X, Wang Y, Liu L, Ma X, Morgan L, Xian Y, Schwamm L, Wang Y. Rationale and design of a stepped wedge cluster randomised trial to improve acute reperfusion treatment quality for stroke: IMPROVE stroke care in China. Stroke And Vascular Neurology 2022, 7: 451-456. PMID: 35354662, PMCID: PMC9614172, DOI: 10.1136/svn-2021-001461.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIntravenous thrombolysisReperfusion therapyEndovascular thrombectomyEligible patientsPrimary outcomeWedge clusterQuality improvement interventionsMixed-effects logistic regressionTreatment qualityIntraclass correlation coefficientReperfusion treatmentHospital delayIschemic strokeStroke centersTreat principleStroke careEfficacy analysisChina trialEffective treatmentNumber of casesImprovement interventionsPatientsComprehensive interventionLogistic regression
2009
Case volumes of intra-arterial and intravenous treatment of ischemic stroke in the USA
Hirsch J, Yoo A, Nogueira R, Verduzco L, Schwamm L, Pryor J, Rabinov J, González R. Case volumes of intra-arterial and intravenous treatment of ischemic stroke in the USA. Journal Of NeuroInterventional Surgery 2009, 1: 27. PMID: 21994101, DOI: 10.1136/jnis.2009.000166.Peer-Reviewed Original ResearchConceptsIntra-arterial therapyNumber of patientsT-PA useStroke centersIschemic strokeCase volumeStroke therapyIntra-arterial reperfusion therapyIntravenous tissue plasminogen activatorIntra-arterial stroke therapyPercentage of patientsLarge vessel occlusionCases/yearTissue plasminogen activatorMassachusetts General HospitalReperfusion therapyIntravenous treatmentStroke casesGeneral HospitalNumber of casesPatientsTherapyStrokeLiterature searchPlasminogen activator