2014
Time and Diffusion Lesion Size in Major Anterior Circulation Ischemic Strokes
Hakimelahi R, Vachha B, Copen W, Papini G, He J, Higazi M, Lev M, Schaefer P, Yoo A, Schwamm L, González R. Time and Diffusion Lesion Size in Major Anterior Circulation Ischemic Strokes. Stroke 2014, 45: 2936-2941. PMID: 25190444, DOI: 10.1161/strokeaha.114.005644.Peer-Reviewed Original ResearchConceptsAnterior circulation ischemic strokeMiddle cerebral artery occlusionDiffusion-weighted imagingCerebral artery occlusionStroke onsetIschemic strokeInfarct sizeDWI lesionsInfarct volumeArtery occlusionIntravenous tissue-type plasminogen activatorProximal middle cerebral arteryDistal internal carotid arteryAcute infarct volumeDWI lesion volumeMajority of patientsMiddle cerebral arteryInternal carotid arteryAcute infarct sizeSame inclusion criteriaTraditional time windowTissue-type plasminogen activatorCerebral perfusionConsecutive patientsInfarct growth
1997
Diffusion-weighted imaging discriminates between cytotoxic and vasogenic edema in a patient with eclampsia.
Schaefer P, Buonanno F, Gonzalez R, Schwamm L. Diffusion-weighted imaging discriminates between cytotoxic and vasogenic edema in a patient with eclampsia. Stroke 1997, 28: 1082-5. PMID: 9158653, DOI: 10.1161/01.str.28.5.1082.Peer-Reviewed Original ResearchConceptsT2 hyperintense signal abnormalityDiffusion-weighted imagingHyperintense signal abnormalitiesVasogenic edemaSignal abnormalitiesRoutine MRIMajority of patientsPermanent neurological impairmentReversible neurological deficitsSubcortical white matterAdjacent gray matterDifferent treatment protocolsPathophysiology of eclampsiaEcho-planar diffusion-weighted imagingEclamptic patientsIschemic encephalopathyNeurological deficitsPosterior predominancePatient groupDiffusion-weighted imagesCytotoxic edemaNeurological impairmentPremature twinsTreatment protocolEdema