2014
Exposing Hidden Truncation-Related Errors in Acute Stroke Perfusion Imaging
Copen W, Deipolyi A, Schaefer P, Schwamm L, González R, Wu O. Exposing Hidden Truncation-Related Errors in Acute Stroke Perfusion Imaging. American Journal Of Neuroradiology 2014, 36: 638-645. PMID: 25500309, PMCID: PMC7964314, DOI: 10.3174/ajnr.a4186.Peer-Reviewed Original ResearchConceptsPerfusion scanVolume of lesionsScan durationSymptom onsetAcute infarctsHemodynamic measurementsLesion reversalClinical trialsLesion volumePatient managementPerfusion MRPerfusion imagingInjected contrast agentPerfusion imagesPatient CTLesionsDurationMTTCTLong scan durationScansContrast agentsShort scan durationTmaxPerfusion estimates
2012
Reliability of cerebral blood volume maps as a substitute for diffusion‐weighted imaging in acute ischemic stroke
deIpolyi A, Wu O, Macklin E, Schaefer P, Schwamm L, Gonzalez R, Copen W. Reliability of cerebral blood volume maps as a substitute for diffusion‐weighted imaging in acute ischemic stroke. Journal Of Magnetic Resonance Imaging 2012, 36: 1083-1087. PMID: 22761110, PMCID: PMC4110961, DOI: 10.1002/jmri.23740.Peer-Reviewed Original ResearchConceptsDiffusion-weighted MRIAcute ischemic strokeCerebral blood volume mapsBlood volume mapsCBV mapsDWI lesionsIschemic strokeProportion of lesionsScan durationDiffusion-weighted imagingAcute strokeStroke onsetInfarct coreContralateral hemisphereRegional CBVMR perfusionVolume mapsLesion centerLesionsCBVStrokeShort durationPerfusionDurationLinear regression
2008
Quantitative Assessment of Core/Penumbra Mismatch in Acute Stroke
Schaefer P, Barak E, Kamalian S, Gharai L, Schwamm L, Gonzalez R, Lev M. Quantitative Assessment of Core/Penumbra Mismatch in Acute Stroke. Stroke 2008, 39: 2986-2992. PMID: 18723425, DOI: 10.1161/strokeaha.107.513358.Peer-Reviewed Original ResearchConceptsCT perfusionPatient selectionInfarct coreAcute middle cerebral artery strokeMiddle cerebral artery strokePreferred imaging methodStroke clinical trialsAcute strokeArtery strokeStroke trialsTrial enrollmentClinical trialsLesion volumeMR perfusionIschemic regionBlood volumeTime abnormalitiesVolume thresholdLesion sizeQuantitative CTPerfusionAdvanced MRCT coverageLesionsMR diffusion
2004
Characterization and evolution of diffusion MR imaging abnormalities in stroke patients undergoing intra-arterial thrombolysis.
Schaefer P, Hassankhani A, Putman C, Sorensen A, Schwamm L, Koroshetz W, Gonzalez R. Characterization and evolution of diffusion MR imaging abnormalities in stroke patients undergoing intra-arterial thrombolysis. American Journal Of Neuroradiology 2004, 25: 951-7. PMID: 15205129, PMCID: PMC7975652.Peer-Reviewed Original ResearchConceptsIntra-arterial thrombolysisDiffusion-weighted imagingDWI findingsDWI ratioADC ratioReperfusion therapyAcute strokeApparent diffusion coefficientInitial diffusion-weighted imagingPretreatment diffusion-weighted imagingADC valuesRespective mean changesEventual infarctionAcute occlusionAnterior circulationStroke patientsLesion volumeMean changePatientsThrombolysisLesion growthMR imagingTissue viabilityLesionsInfarction
2001
Unilateral Temporal Lobe Stroke Causing Ischemic Transient Global Amnesia: Role for Diffusion‐Weighted Imaging in the Initial Evaluation
Greer D, Schaefer P, Schwamm L. Unilateral Temporal Lobe Stroke Causing Ischemic Transient Global Amnesia: Role for Diffusion‐Weighted Imaging in the Initial Evaluation. Journal Of Neuroimaging 2001, 11: 317-319. PMID: 11462302, DOI: 10.1111/j.1552-6569.2001.tb00054.x.Peer-Reviewed Original ResearchConceptsTransient global amnesiaDiffusion-weighted imagingInitial diffusion-weighted imagingLeft mesial temporal lobeSmall ischemic lesionsApparent diffusion coefficient imagingMesial temporal lobeOnset of symptomsT2-weighted imagingIschemic infarctIschemic lesionsAcute infarctsGlobal amnesiaTemporal lobeInitial evaluationEarly detectionInfarctsLesionsSymptomsImagingMagnetic resonanceDaysIschemiaEmboliPatients