2014
Time and Diffusion Lesion Size in Major Anterior Circulation Ischemic Strokes
Hakimelahi R, Vachha B, Copen W, Papini G, He J, Higazi M, Lev M, Schaefer P, Yoo A, Schwamm L, González R. Time and Diffusion Lesion Size in Major Anterior Circulation Ischemic Strokes. Stroke 2014, 45: 2936-2941. PMID: 25190444, DOI: 10.1161/strokeaha.114.005644.Peer-Reviewed Original ResearchConceptsAnterior circulation ischemic strokeMiddle cerebral artery occlusionDiffusion-weighted imagingCerebral artery occlusionStroke onsetIschemic strokeInfarct sizeDWI lesionsInfarct volumeArtery occlusionIntravenous tissue-type plasminogen activatorProximal middle cerebral arteryDistal internal carotid arteryAcute infarct volumeDWI lesion volumeMajority of patientsMiddle cerebral arteryInternal carotid arteryAcute infarct sizeSame inclusion criteriaTraditional time windowTissue-type plasminogen activatorCerebral perfusionConsecutive patientsInfarct growth
2013
Hospital Acquired Pneumonia Is Linked to Right Hemispheric Peri-Insular Stroke
Kemmling A, Lev MH, Payabvash S, Betensky RA, Qian J, Masrur S, Schwamm LH. Hospital Acquired Pneumonia Is Linked to Right Hemispheric Peri-Insular Stroke. PLOS ONE 2013, 8: e71141. PMID: 23951094, PMCID: PMC3737185, DOI: 10.1371/journal.pone.0071141.Peer-Reviewed Original ResearchConceptsHemispheric infarctsBrain regionsConsecutive acute stroke patientsConditional logistic regression modelsHospital-Acquired PneumoniaRight hemispheric infarctAcute stroke patientsInsular cortex volumeVolume-based variablesSpecific brain regionsLogistic regression modelsAcquired PneumoniaControl patientsMajor complicationsBrainstem strokeImmune suppressionInfarct sizeStroke patientsAutonomic modulationClinical variablesAdmission imagingInfarct locationUnivariate analysisImmune mechanismsCortex volume
2004
ASPECTS on CTA Source Images Versus Unenhanced CT
Coutts S, Lev M, Eliasziw M, Roccatagliata L, Hill M, Schwamm L, Pexman J, Koroshetz W, Hudon M, Buchan A, Gonzalez R, Demchuk A. ASPECTS on CTA Source Images Versus Unenhanced CT. Stroke 2004, 35: 2472-2476. PMID: 15486327, DOI: 10.1161/01.str.0000145330.14928.2a.Peer-Reviewed Original ResearchConceptsAlberta Stroke Program Early CT ScoreCTA-SI Alberta Stroke Program Early CT ScoreCT angiography source imagesBaseline Alberta Stroke Program Early CT ScoreIschemic changesFavorable outcomeNCCT-Alberta Stroke Program Early CT ScoreAcute ischemic strokeFinal infarct sizeFinal infarct volumeFavorable patient outcomesNormal CT scanRate ratioCTA source imagesM2 occlusionsInfarct volumeIschemic strokeProximal occlusionSymptom onsetClinical outcomesMedian timeCT scoreInfarct sizePatient outcomesBaseline NCCT
2002
Predicting cerebral ischemic infarct volume with diffusion and perfusion MR imaging.
Schaefer P, Hunter G, He J, Hamberg L, Sorensen A, Schwamm L, Koroshetz W, Gonzalez R. Predicting cerebral ischemic infarct volume with diffusion and perfusion MR imaging. American Journal Of Neuroradiology 2002, 23: 1785-94. PMID: 12427640, PMCID: PMC8185825.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBlood Flow VelocityBrain IschemiaCerebral InfarctionCerebrovascular CirculationDiffusion Magnetic Resonance ImagingFalse Positive ReactionsFemaleFollow-Up StudiesHumansIschemic Attack, TransientMagnetic Resonance AngiographyMaleMiddle AgedObserver VariationPredictive Value of TestsSensitivity and SpecificityTime FactorsConceptsCerebral blood flowCerebral blood volumeFinal infarct volumeInfarct volumeDW imagingLesion growthAcute ischemic stroke symptomsHemodynamic imagesAcute ischemic infarctionIschemic infarct volumeInitial clinical assessmentFinal discharge diagnosisFinal infarct sizeHours of onsetIschemic stroke symptomsPerfusion MR imagingPerfusion-weighted imagesAcute strokeIschemic infarctionStroke symptomsAcute infarctionAcute lesionsDischarge diagnosisInfarct sizeAltered perfusion
2001
CT Perfusion Imaging versus MR Diffusion Weighted Imaging: Prediction of Final Infarct Size in Hyperacute Stroke
Berzin T, Lev M, Goodman D, Koroshetz W, Hunter G, Hamberg L, Buonanno F, Putman C, Budzik R, Eskey C, Schwamm L, Gonzalez R. CT Perfusion Imaging versus MR Diffusion Weighted Imaging: Prediction of Final Infarct Size in Hyperacute Stroke. Stroke 2001, 32: 317-317. DOI: 10.1161/str.32.suppl_1.317.Peer-Reviewed Original ResearchFinal infarct sizeCT perfusion imagingInfarct sizeStroke onsetHyperacute strokeDWI volumePerfusion imagingFinal infarct volumeBrain CT scanningHyperacute stroke patientsSame patient populationMR-Diffusion Weighted ImagingSteady-state administrationCT angiographic imagesDiffusion-Weighted ImagingDWI imagingInfarct volumeConsecutive patientsIndependent predictorsIschemic volumeStroke patientsPatient populationCTP imagingBlood volumePatients