2018
Comparison of Acute Ischemic Stroke Care and Outcomes Between Comprehensive Stroke Centers and Primary Stroke Centers in the United States
Man S, Zhao X, Uchino K, Hussain M, Smith E, Bhatt D, Xian Y, Schwamm L, Shah S, Khan Y, Fonarow G. Comparison of Acute Ischemic Stroke Care and Outcomes Between Comprehensive Stroke Centers and Primary Stroke Centers in the United States. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004512. PMID: 29794035, PMCID: PMC5978771, DOI: 10.1161/circoutcomes.117.004512.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCertificationComprehensive Health CareDelivery of Health Care, IntegratedEmergency Service, HospitalEndovascular ProceduresFemaleHospital MortalityHospitalsHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePatient AdmissionPatient TransferQuality ImprovementQuality Indicators, Health CareRecovery of FunctionRegistriesRisk AssessmentRisk FactorsStrokeThrombolytic TherapyTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesConceptsPrimary stroke centerEmergency department admissionsStroke center certificationAcute ischemic strokeIschemic stroke careStroke centersStroke careDepartment admissionsHospital mortalityHospital outcomesIntravenous tPAIschemic strokeCenter certificationTPA timeComprehensive Stroke Center (CSC) certificationAcute ischemic stroke careMultivariable logistic regression modelAcute reperfusion therapyAcute stroke triageBrain Attack CoalitionDefect-free careComprehensive stroke centerOverall care qualityLogistic regression modelsGuidelines-StrokeAbsence of July Phenomenon in Acute Ischemic Stroke Care Quality and Outcomes
Gonzalez‐Castellon M, Ju C, Xian Y, Hernandez A, Fonarow G, Schwamm L, Smith E, Bhatt D, Reeves M, Willey J. Absence of July Phenomenon in Acute Ischemic Stroke Care Quality and Outcomes. Journal Of The American Heart Association 2018, 7: e007685. PMID: 29386207, PMCID: PMC5850252, DOI: 10.1161/jaha.117.007685.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaClinical CompetenceFemaleHealth StatusHospitals, TeachingHumansInternship and ResidencyMaleMiddle AgedOutcome and Process Assessment, Health CarePatient AdmissionPatient DischargePersonnel Staffing and SchedulingQuality Indicators, Health CareRegistriesStrokeTime FactorsTime-to-TreatmentTreatment OutcomeUnited StatesConceptsGuidelines-Stroke programProportion of patientsAcute ischemic strokeIschemic strokeJuly phenomenonHospital outcomesAcute ischemic stroke care qualityMultivariable logistic regression modelCare qualityDefect-free careStroke care qualityStroke performance measuresSymptomatic intracranial hemorrhageHours of admissionLower care qualityLogistic regression modelsNeedle timeIntracranial hemorrhageMultivariable analysisAdverse outcomesNonteaching hospitalsTomography timePatientsClinical metricsHospital
2016
Temporal Trends in Care and Outcomes of Patients Receiving Fibrinolytic Therapy Compared to Primary Percutaneous Coronary Intervention: Insights From the Get With The Guidelines Coronary Artery Disease (GWTG‐CAD) Registry
Hira R, Bhatt D, Fonarow G, Heidenreich P, Ju C, Virani S, Bozkurt B, Petersen L, Hernandez A, Schwamm L, Eapen Z, Albert M, Liang L, Matsouaka R, Peterson E, Jneid H. Temporal Trends in Care and Outcomes of Patients Receiving Fibrinolytic Therapy Compared to Primary Percutaneous Coronary Intervention: Insights From the Get With The Guidelines Coronary Artery Disease (GWTG‐CAD) Registry. Journal Of The American Heart Association 2016, 5: e004113. PMID: 27792640, PMCID: PMC5121508, DOI: 10.1161/jaha.116.004113.Peer-Reviewed Original ResearchMeSH KeywordsAgedCohort StudiesDatabases, FactualFemaleFibrinolytic AgentsGuideline AdherenceHospital MortalityHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePercutaneous Coronary InterventionPractice Guidelines as TopicRegistriesST Elevation Myocardial InfarctionThrombolytic TherapyTime-to-TreatmentConceptsPrimary percutaneous coronary interventionST-elevation myocardial infarctionDefect-free careUse of fibrinolysisPercutaneous coronary interventionPCI-capable hospitalsNeedle timeHospital mortalitySTEMI patientsBalloon timeCoronary interventionMedian doorUse of PCIGuidelines-Coronary Artery Disease databaseGuidelines-Coronary Artery Disease registryCoronary Artery Disease registryHospital mortality outcomesOutcomes of patientsMinutes of arrivalPPCI patientsTimely reperfusionReperfusion therapyFibrinolytic therapyMortality outcomesMyocardial infarction
2015
Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack
O'Brien E, Zhao X, Fonarow G, Schulte P, Dai D, Smith E, Schwamm L, Bhatt D, Xian Y, Saver J, Reeves M, Peterson E, Hernandez A. Quality of Care and Ischemic Stroke Risk After Hospitalization for Transient Ischemic Attack. Circulation Cardiovascular Quality And Outcomes 2015, 8: s117-s124. PMID: 26515199, DOI: 10.1161/circoutcomes.115.002048.Peer-Reviewed Original ResearchConceptsTransient ischemic attackDefect-free careIschemic strokeIschemic stroke riskQuality of careIschemic attackStroke riskCare measuresRisk scoreOverall hospital admission rateRisk score quintilesYear post dischargeLow-risk patientsHospital admission ratesIschemic stroke admissionsPrevious myocardial infarctionAbsence of strokeMedicare inpatient claimsCox proportional hazardsModerate discriminative performanceTIA patientsCause mortalityCessation counselingStroke admissionsBaseline demographics
2013
Quality of Care and Outcomes for In-Hospital Ischemic Stroke
Cumbler E, Wald H, Bhatt D, Cox M, Xian Y, Reeves M, Smith E, Schwamm L, Fonarow G. Quality of Care and Outcomes for In-Hospital Ischemic Stroke. Stroke 2013, 45: 231-238. PMID: 24253540, DOI: 10.1161/strokeaha.113.003617.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain IschemiaCohort StudiesComorbidityConfidence IntervalsDatabases, FactualFemaleGuideline AdherenceHumansMaleMiddle AgedOdds RatioQuality ImprovementQuality of Health CareRegistriesRetrospective StudiesSocioeconomic FactorsStrokeThrombolytic TherapyTreatment OutcomeConceptsHospital strokeIschemic strokeSevere strokePatient characteristicsIn-Hospital Ischemic StrokeProcess-based quality measuresCommunity-onset strokeDefect-free careGuidelines-Stroke databaseRetrospective cohort studyThromboembolic risk factorsProportion of patientsHospital ischemic strokeAmerican Heart AssociationTargeted quality improvement effortsQuality of careProsthetic heart valvesQuality improvement effortsHospital mortalityComorbid illnessesCohort studyHeart failureAtrial fibrillationCarotid stenosisHeart Association
2012
Regional Variation in Recommended Treatments for Ischemic Stroke and TIA
Allen NB, Kaltenbach L, Goldstein LB, Olson DM, Smith EE, Peterson ED, Schwamm L, Lichtman JH. Regional Variation in Recommended Treatments for Ischemic Stroke and TIA. Stroke 2012, 43: 1858-1864. PMID: 22588262, DOI: 10.1161/strokeaha.112.652305.Peer-Reviewed Original ResearchConceptsDefect-free careLipid-lowering medicationsTissue-type plasminogen activatorLower oddsIschemic strokeIntravenous tissue-type plasminogen activatorSecondary stroke prevention treatmentDeep vein thrombosis prophylaxisTissue-type plasminogen activator administrationNational quality improvement programPlasminogen activatorGuideline-recommended treatmentGuidelines-Stroke hospitalsTransient ischemic attackQuarter of patientsStroke prevention treatmentBetter patient outcomesWeight loss educationQuality Improvement ProgramEligible patientsIschemic attackThrombosis prophylaxisPatient demographicsStroke treatmentMedical historyCare and Outcomes of Asian-American Acute Myocardial Infarction Patients
Qian F, Ling F, Deedwania P, Hernandez A, Fonarow G, Cannon C, Peterson E, Peacock W, Kaltenbach L, Laskey W, Schwamm L, Bhatt D. Care and Outcomes of Asian-American Acute Myocardial Infarction Patients. Circulation Cardiovascular Quality And Outcomes 2012, 5: 126-133. PMID: 22235068, DOI: 10.1161/circoutcomes.111.961987.Peer-Reviewed Original ResearchConceptsGuidelines-Coronary Artery Disease programAcute myocardial infarctionAMI patientsDisease programsBalloon timeWhite patientsAcute myocardial infarction patientsAMI performance measuresDefect-free careHospital mortality rateEvidence-based careAmerican Heart AssociationMyocardial infarction patientsAsian American patientsUnited States CentersHospital mortalityCessation counselingUnadjusted mortalityHeart failureHeart AssociationInfarction patientsMyocardial infarctionHigh prevalenceClinical careMortality rate
2009
Quality of Care in Women With Ischemic Stroke in the GWTG Program
Reeves M, Fonarow G, Zhao X, Smith E, Schwamm L. Quality of Care in Women With Ischemic Stroke in the GWTG Program. Stroke 2009, 40: 1127-1133. PMID: 19211482, DOI: 10.1161/strokeaha.108.543157.Peer-Reviewed Original ResearchConceptsQuality of careIschemic strokeAcute ischemic stroke admissionsMultivariable logistic regression modelDefect-free careGuidelines-Stroke programGWTG-Stroke programWorse poststroke outcomesIschemic stroke admissionsPast medical historySex differencesLogistic regression modelsSex-based differencesStroke admissionsCrude mortalityAtrial fibrillationMedical historyPoststroke outcomesHeart diseaseRisk adjustmentCareWomenFurther studiesMenStroke