2010
The “Golden Hour” and Acute Brain Ischemia
Saver J, Smith E, Fonarow G, Reeves M, Zhao X, Olson D, Schwamm L. The “Golden Hour” and Acute Brain Ischemia. Stroke 2010, 41: 1431-1439. PMID: 20522809, PMCID: PMC2909671, DOI: 10.1161/strokeaha.110.583815.Peer-Reviewed Original ResearchConceptsIschemic stroke patientsHospital emergency departmentIntravenous thrombolytic therapyAcute brain ischemiaNeedle timeThrombolytic therapyStroke patientsEmergency departmentGolden hourBrain ischemiaGreater stroke severityGuidelines-Stroke databaseQuarter of patientsHours of onsetHours patientsStroke severityDoor timeEarly presentationPatientsWell timeStudy periodTherapyIschemiaOnset timeMinutes
1999
Normal diffusion-weighted MRI during stroke-like deficits
Ay H, Buonanno F, Rordorf G, Schaefer P, Schwamm L, Wu O, Gonzalez R, Yamada K, Sorensen G, Koroshetz W. Normal diffusion-weighted MRI during stroke-like deficits. Neurology 1999, 52: 1784-1792. PMID: 10371524, DOI: 10.1212/wnl.52.9.1784.Peer-Reviewed Original ResearchConceptsDiffusion-weighted MRICerebral ischemic eventsDWI abnormalitiesStroke mimicsIschemic eventsAcute ischemic strokeIschemic brain injuryTransient global amnesiaIschemic causePathophysiologic diagnosisLacunar syndromeNonischemic causesIschemic strokeLacunar infarctionNeurologic deficitsBrain ischemiaConsecutive patientsSuch patientsRadiologic dataFinal diagnosisBrain injuryCortical syndromesFunctional disordersEarly diagnosisGlobal amnesia