Featured Publications
Total Hip Arthroplasty Imageless Navigation Does Not Reduce 90-Day Adverse Events or Five-Year Revisions in a Large National Cohort
Jayaram R, Gillinov S, Caruana D, Kammien A, Joo P, Rubin L, Grauer J. Total Hip Arthroplasty Imageless Navigation Does Not Reduce 90-Day Adverse Events or Five-Year Revisions in a Large National Cohort. The Journal Of Arthroplasty 2022, 38: 862-867. PMID: 36529197, DOI: 10.1016/j.arth.2022.12.012.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyAdverse eventsImageless navigationMultivariate analysisLarge national administrative databaseElixhauser comorbidity index scorePrimary total hip arthroplastyComorbidity Index scoreFive-year incidencePostoperative adverse eventsNational administrative databaseLarge national cohortLarge national databaseCause revisionTHA patientsWound dehiscenceNational cohortTHA casesAdministrative databasesDislocation rateHip arthroplastyHigher oddsNavigation groupIndex scoreComputer navigationUnicompartmental Knee Arthroplasty in Octogenarians: A National Database Analysis Including Over 700 Octogenarians
Moore HG, Schneble CA, Kahan JB, Grauer JN, Rubin LE. Unicompartmental Knee Arthroplasty in Octogenarians: A National Database Analysis Including Over 700 Octogenarians. Arthroplasty Today 2022, 15: 55-60. PMID: 35399988, PMCID: PMC8991237, DOI: 10.1016/j.artd.2022.02.009.Peer-Reviewed Original ResearchUnicompartmental knee arthroplastyAdverse eventsMedical comorbiditiesKnee arthroplastyNational Surgical Quality Improvement Program databaseLarge national surgical databaseQuality Improvement Program databaseHigher comorbidity burdenMinor adverse eventsPostoperative adverse eventsSerious adverse eventsImprovement Program databaseProlonged hospital stayUrinary tract infectionDay of surgeryNational database analysisNational surgical databaseShort-term mortalityMultivariate regression analysisComorbidity burdenOctogenarian cohortHospital lengthHospital stayNonhome dischargeSelect patientsWhat Factors Affect Whether Patients Return to the Same Surgeon to Replace the Contralateral Joint? A Study of Over 200,000 Patients
Moore HG, Schneble CA, Kahan JB, Sculco PK, Grauer JN, Rubin LE. What Factors Affect Whether Patients Return to the Same Surgeon to Replace the Contralateral Joint? A Study of Over 200,000 Patients. The Journal Of Arthroplasty 2021, 37: 425-430. PMID: 34871749, DOI: 10.1016/j.arth.2021.11.036.Peer-Reviewed Original ResearchConceptsBilateral total hip arthroplastyTotal knee arthroplastyTotal hip arthroplastyContralateral total hip arthroplastySame surgeonDifferent surgeonsAdverse eventsContralateral jointGreater oddsSurgery-related adverse eventsBilateral total knee arthroplastyNational Provider Identifier numberFirst joint replacementFirst total hip arthroplastyPossible independent predictorsContralateral replacementIndependent predictorsSicker patientsKnee arthroplastyAdministrative databasesHip arthroplastyLower oddsPatientsArthroplastyJoint replacementEssential elements of an outpatient total joint replacement programme.
Li J, Rubin LE, Mariano ER. Essential elements of an outpatient total joint replacement programme. Current Opinion In Anaesthesiology 2019, 32: 643-648. PMID: 31356361, DOI: 10.1097/aco.0000000000000774.Peer-Reviewed Original ResearchMeSH KeywordsAmbulatory Surgical ProceduresArthroplasty, Replacement, HipArthroplasty, Replacement, KneeCritical PathwaysFeasibility StudiesHealth Plan ImplementationHumansLength of StayMedicaidMedicarePatient Education as TopicPatient ReadmissionPatient SatisfactionPatient SelectionPostoperative ComplicationsProgram EvaluationTreatment OutcomeUnited StatesConceptsTotal joint arthroplastyOutpatient total joint arthroplastyPatient satisfactionLong-term functional outcomePatient/family educationTotal knee arthroplasty patientsOpioid-sparing analgesiaShort-term complicationsTotal joint replacement programKnee arthroplasty patientsSubset of patientsStandardized clinical pathwayPositive surgical outcomesProper patient selectionJoint replacement programEvidence-based guidanceNew care paradigmPostdischarge planningAdverse eventsArthroplasty patientsPatient selectionSurgical outcomesFunctional outcomeOutpatient surgeryInpatient proceduresIncreased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients.
Ottesen TD, McLynn RP, Galivanche AR, Bagi PS, Zogg CK, Rubin LE, Grauer JN. Increased complications in geriatric patients with a fracture of the hip whose postoperative weight-bearing is restricted: an analysis of 4918 patients. The Bone & Joint Journal 2018, 100-B: 1377-1384. PMID: 30295535, DOI: 10.1302/0301-620x.100b10.bjj-2018-0489.r1.Peer-Reviewed Original ResearchConceptsWeight-bearing restrictionsLength of stayAdverse eventsPostoperative weight-bearing restrictionsMajor adverse eventsEvidence-based guidelinesBone Joint JOperating theatreMultivariate regression analysisMultivariate oddsFrail patientsThromboembolic eventsElderly patientsHip fractureGeriatric patientsProcedural characteristicsInclusion criteriaPatientsGreater riskProcedural factorsHipReadmissionDeliriumTransfusionSurgery
2024
Ulcerative Colitis Patients are at Increased Risk for Adverse Events Following Total Hip Arthroplasty
Oghenesume O, Gouzoulis M, Ratnasamy P, Dhodapkar M, Grauer J, Rubin L. Ulcerative Colitis Patients are at Increased Risk for Adverse Events Following Total Hip Arthroplasty. The Journal Of Arthroplasty 2024 PMID: 39515400, DOI: 10.1016/j.arth.2024.10.134.Peer-Reviewed Original ResearchPostoperative adverse eventsAdverse eventsClasses of medicationsElixhauser Comorbidity IndexUlcerative colitisPatient ageTotal hip arthroplastyTotal hip arthroplasty patientsFive-year survivalUlcerative colitis patientsArthroplasty patientsPatient's medication regimenHip arthroplasty patientsDisease ulcerative colitisUC patientsColitis patientsComorbidity indexCorticosteroidsPerioperative periodIncreased riskHip arthroplastyPatientsMedication regimenDisease processMatched groupContinuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty
Freedman I, Mercier M, Galivanche A, Sandhu M, Hocevar M, Moore H, Grauer J, Rubin L, Li J. Continuous Adductor Canal Block Compared to Epidural Anesthesia for Total Knee Arthroplasty. Journal Of Pain Research 2024, 17: 3729-3740. PMID: 39559456, PMCID: PMC11572497, DOI: 10.2147/jpr.s462079.Peer-Reviewed Original ResearchContinuous adductor canal blockAdductor canal blockEpidural analgesiaEA patientsNon-home dischargeCanal blockMultivariate analysisIncidence of postoperative adverse eventsPostoperative adverse eventsMorphine equivalentsEpidural anesthesiaAdverse eventsRetrospective analysisHospital lengthProlonged LOSLevel IIIPatientsSteroidsTotal knee arthroplastyAdjuvantTKA patientsLogistic regressionDischarge dispositionAnalgesiaKnee arthroplastyImproved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization. JSES International 2024 DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomes90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. 90-Day Complication and Readmission Rates for Geriatric Patients With Hip Fracture at Different Time Points From COVID-19 Positivity: A Database Study. JAAOS Global Research And Reviews 2024, 8: e24.00069. PMID: 39330875, PMCID: PMC11412709, DOI: 10.5435/jaaosglobal-d-24-00069.Peer-Reviewed Original ResearchConceptsHip fracture surgeryHip fractureGeriatric patientsFracture surgeryAdverse eventsRate of minor adverse eventsCOVID-19 diagnosisWeeks of surgeryMinor adverse eventsTime pointsAssociated with increased oddsComplication rateAssess complicationsCOVID-19 positivityCOVID-19 infectionMultivariate analysisSurgeryComplicationsPatientsDatabase studyReadmission ratesCare algorithmWeeksDiagnosisCOVID-19Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerveTotal Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024, 39: 2421-2426. PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplastyRisk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients
Smith-Voudouris J, Rubin L, Grauer J. Risk of Adverse Events Following Total Knee Arthroplasty in Asthma Patients. Journal Of The American Academy Of Orthopaedic Surgeons 2024, 32: 543-549. PMID: 38657178, DOI: 10.5435/jaaos-d-23-01142.Peer-Reviewed Original ResearchAdverse eventsTotal knee arthroplastyElixhauser Comorbidity IndexOne-tenth of patientsAsthma patientsOdds of adverse eventsRisk of adverse eventsIncreasing severity of asthmaMultivariate logistic regressionInflammatory airway diseasesSeverity of asthmaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesAggregate adverse eventsAdult patientsNon-pulmonaryAirway diseaseComorbidity indexMultivariate analysisPatient factorsAsthma groupEmergency department visitsPatientsIncreased oddsOutcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation
Jiang W, Sanchez J, Dhodapkar M, Radford Z, Rubin L, Grauer J. Outcomes Following Total Hip Arthroplasty in Patients Who Have Von Willebrand Disease Depend on Postoperative Anticoagulation. The Journal Of Arthroplasty 2024, 39: 2088-2093. PMID: 38462141, DOI: 10.1016/j.arth.2024.03.004.Peer-Reviewed Original ResearchVon Willebrand diseaseVon Willebrand disease patientsRevision-free survivalVenous thromboembolismAdverse eventsOdds of venous thromboembolismTotal hip arthroplastyIncreased oddsDefects of von Willebrand factorCongenital bleeding disordersPatients to dateQualitative defects of von Willebrand factorPostoperative adverse eventsThrombotic adverse eventsMultivariate logistic regressionAutosomal dominant conditionVon Willebrand factorElixhauser Comorbidity IndexBleeding disordersPostoperative anticoagulationAdult patientsCompare bleedingPrescription patternsQualitative defectsWillebrand disease
2023
Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Kaszuba S, Rubin L, Grauer J. Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 309-315. PMID: 38165956, DOI: 10.5435/jaaos-d-23-00783.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyUrinary tract infectionPostoperative eventsCystic fibrosisPerioperative outcomesAdverse eventsTract infectionsPleural effusionKnee arthroplastyControl subjectsRevision rateAcute kidney injuryElixhauser Comorbidity IndexRisk of surgeryMultivariable logistic regressionComorbidity indexKidney injuryPerioperative complicationsRespiratory failureTKA patientsCardiac eventsPearlDiver databaseImplant survivalTotal hipPatients With Down Syndrome and Total Hip and Total Knee Arthroplasty: Outcome Measures Show Increased Risk of Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Frumberg D, Rubin L, Grauer J. Patients With Down Syndrome and Total Hip and Total Knee Arthroplasty: Outcome Measures Show Increased Risk of Perioperative Complications. JAAOS Global Research And Reviews 2023, 7: e23.00108. PMID: 38054749, PMCID: PMC10697628, DOI: 10.5435/jaaosglobal-d-23-00108.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyAcute kidney injuryUrinary tract infectionAdverse eventsDown syndromePostoperative eventsKnee arthroplastyRevision ratePerioperative risk assessmentMinor adverse eventsOutcomes of patientsMultivariable logistic regressionTotal joint arthroplastyPatient/family counselingKidney injuryPerioperative complicationsTKA patientsAdult patientsTract infectionsDS patientsIncreased riskTotal hipCare pathwayJoint arthroplastyTotal Hip Arthroplasty in Patients Who Have Marfan Syndrome: Adverse Events and 5-Year Revision Rates
Day W, Jayaram R, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Marfan Syndrome: Adverse Events and 5-Year Revision Rates. The Journal Of Arthroplasty 2023, 39: s275-s278. PMID: 37952742, DOI: 10.1016/j.arth.2023.10.052.Peer-Reviewed Original ResearchTotal hip arthroplastyAdverse eventsMarfan syndromeMultivariable analysisHip arthroplastyUnderwent total hip arthroplastyPostoperative adverse eventsVenous thromboembolic eventsPerioperative care pathwaysUrinary tract infectionConnective tissue diseaseLog-rank testRare disease populationComorbidity indexThromboembolic eventsCardiac eventsPostoperative courseTract infectionsAdult patientsTissue diseaseHip pathologyRevision rateCare pathwayDisease populationGreater oddsTotal Knee Arthroplasty: Variables Affecting 90-day Overall Reimbursement
Halperin S, Dhodapkar M, Radford Z, Li M, Rubin L, Grauer J. Total Knee Arthroplasty: Variables Affecting 90-day Overall Reimbursement. The Journal Of Arthroplasty 2023, 38: 2259-2263. PMID: 37279847, DOI: 10.1016/j.arth.2023.05.072.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTKA patientsPrimary total knee arthroplastyPostoperative emergency departmentPostoperative adverse eventsRisk of readmissionMultivariable linear regressionPerioperative periodPostoperative eventsAdverse eventsAppropriate patientsKnee osteoarthritisEmergency departmentPatients surgeryKnee arthroplastyOncologic indicationsCost-containment strategiesSurgical proceduresExclusion criteriaPatientsOptimize deliveryOverall reimbursementAdmissionReimbursementGreater increaseComparison of Differences in Surgical Complications Between Fellowship-Trained Orthopedic Foot and Ankle Surgeons and All Other Orthopedic Surgeons Using the ABOS Database.
Ottesen T, Pathak N, Mercier M, Kirwin D, Lukasiewicz A, Grauer J, Rubin L. Comparison of Differences in Surgical Complications Between Fellowship-Trained Orthopedic Foot and Ankle Surgeons and All Other Orthopedic Surgeons Using the ABOS Database. Orthopedics 2023, 46: e237-e243. PMID: 36719412, DOI: 10.3928/01477447-20230125-05.Peer-Reviewed Original ResearchConceptsSurgical complicationsOrthopaedic surgeonsFellowship trainingBinary multivariate logistic regressionFellowship-trained orthopedic footFellowship-trained orthopaedic surgeonsAnkle fracture repairSpecific patient comorbiditiesSurgeon-reported complicationsTrauma fellowship trainingMultivariate logistic regressionFellowship-trained surgeonsOrthopaedic Surgery databaseComplexity of casesAmerican BoardOrthopaedic FootAdverse eventsPatient comorbiditiesComorbidity dataABOS databaseAnkle surgeryPatient complicationsSurgery DatabaseSurgical complexityInclusion criteria
2022
Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study
Joo P, Modrak M, Park N, Brand J, Rubin L, Grauer J, Bernstein J. Comparing Venous Thromboembolism Prophylactic Agents After Hip Fracture Surgery: A National Database Study. JAAOS Global Research And Reviews 2022, 6: e22.00228. PMID: 36732301, PMCID: PMC9746777, DOI: 10.5435/jaaosglobal-d-22-00228.Peer-Reviewed Original ResearchConceptsHip fracture surgeryFracture surgeryAdverse eventsOdds ratioProphylactic agentGreater oddsAnticoagulant-naïve patientsDifferent anticoagulant agentsVenous thromboembolism chemoprophylaxisVTE prophylactic agentNational database studyDistal femoral fracturesCoumadin groupLower transfusionVTE prophylaxisVTE ratesPatient characteristicsComorbidity profilesFemoral fracturesChemoprophylactic agentAnticoagulant agentsCoumadinDatabase studyLower oddsPatientsAdmission NarxCare Narcotic Scores Are Associated With Increased Odds of Readmission and Prolonged Length of Hospital Stay After Primary Elective Total Knee Arthroplasty
Galivanche A, Zhu J, Mercier M, McLean R, Wilhelm C, Varthi A, Grauer J, Rubin L. Admission NarxCare Narcotic Scores Are Associated With Increased Odds of Readmission and Prolonged Length of Hospital Stay After Primary Elective Total Knee Arthroplasty. JAAOS Global Research And Reviews 2022, 6: e22.00040. PMID: 36732305, PMCID: PMC9726283, DOI: 10.5435/jaaosglobal-d-22-00040.Peer-Reviewed Original ResearchConceptsPrimary elective total knee arthroplastyElective total knee arthroplastyTotal knee arthroplastyNarcotic scoreOverall opioid usageAdverse eventsTKA patientsHospital stayKnee arthroplastyRisk of AEsOdds of readmissionPrimary TKA patientsPreoperative narcotic useTime of admissionDose-dependent increaseOpioid usagePostoperative outcomesPatient characteristicsProlonged lengthNarcotic useAdverse outcomesSingle institutionRevision surgeryReadmissionPatients