2020
Partially Differentiated Neuroretinal Cells Promote Maturation of the Retinal Pigment Epithelium
Singh D, Chen X, Xia T, Ghiassi-Nejad M, Tainsh L, Adelman RA, Rizzolo LJ. Partially Differentiated Neuroretinal Cells Promote Maturation of the Retinal Pigment Epithelium. Investigative Ophthalmology & Visual Science 2020, 61: 9-9. PMID: 33151282, PMCID: PMC7671856, DOI: 10.1167/iovs.61.13.9.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumRetinal progenitor cellsTransepithelial electrical resistanceNeurosensory retinaPigment epitheliumHuman fetal retinal pigment epitheliumRecoverin-positive cellsFetal retinal pigment epitheliumGanglion cell layerAbility of RPERPE signature genesRed/green opsinTranswell filter insertsStem cellsQuantitative RT-PCRGlial markersHuman stem cellsExpression of rhodopsinInterneuron markersBipolar cellsRetinal culturesRetinaRT-PCRProgenitor cellsPresumptive photoreceptors
2008
A Novel Rabbit Model for Studying RPE Transplantation
Cong L, Sun D, Zhang Z, Jiao W, Rizzolo LJ, Peng S. A Novel Rabbit Model for Studying RPE Transplantation. Investigative Ophthalmology & Visual Science 2008, 49: 4115-4125. PMID: 18502985, PMCID: PMC2568003, DOI: 10.1167/iovs.08-1976.Peer-Reviewed Original ResearchConceptsOptical coherence tomographySubretinal spaceIntact blood-retinal barrierRetinal pigment epithelium (RPE) transplantationRabbit RPEBlood-retinal barrierConfocal scanning laserNovel rabbit modelZonula occludens-1CFDA-SEFunctional RPE monolayerTransepithelial electrical resistanceTransplanted RPEFundus photographyConjunctival flapRPE transplantationTransplantation protocolsLabeled cellsRabbit modelCoherence tomographyOccludens-1RPE cellsRPE monolayerPrimary cultures