2014
Ictal spread of medial temporal lobe seizures with and without secondary generalization: An intracranial electroencephalography analysis
Yoo JY, Farooque P, Chen WC, Youngblood MW, Zaveri HP, Gerrard JL, Spencer DD, Hirsch LJ, Blumenfeld H. Ictal spread of medial temporal lobe seizures with and without secondary generalization: An intracranial electroencephalography analysis. Epilepsia 2014, 55: 289-295. PMID: 24417694, PMCID: PMC4103687, DOI: 10.1111/epi.12505.Peer-Reviewed Original ResearchConceptsSecondary generalizationTemporal lobe seizuresFocal seizuresTemporal cortexMedial temporal lobe seizuresCortical regionsLow-voltage fast activityProminent activationAnteromedial temporal lobe resectionTonic-clonic seizuresSeizure-onset patternsTemporal lobe resectionLateral temporal cortexQuality of lifePosterior lateral temporal cortexTemporal lobe areasIntracranial electroencephalography studyMedial temporal lobe areasMedial temporal lobePosterior lateral temporal regionsIctal spreadHippocampal sclerosisSeizure spreadLobe resectionTemporal lobe
2009
Breathing New Life into the Fight against Sudden Death in Epilepsy
Hirsch LJ. Breathing New Life into the Fight against Sudden Death in Epilepsy. Epilepsy Currents 2009, 9: 137-139. PMID: 19826505, PMCID: PMC2759044, DOI: 10.1111/j.1535-7511.2009.01319.x.Peer-Reviewed Original ResearchLocalization-related epilepsyOxygen desaturationIctal hypoxemiaSecondary generalizationSeizure durationGeneralized convulsionsSeizure localizationContralateral spreadSecondary generalized convulsionsEnd-tidal carbon dioxideIntractable localization-related epilepsyVideo-EEG telemetryMean oxygen saturationSudden unexpected deathBody mass indexOxygen saturation dataDegree of desaturationElectrographic evidenceSeizure spreadConsecutive patientsPartial seizuresMass indexSeizure lateralizationObstructive apnoeaMean duration