2021
Brief potentially ictal rhythmic discharges and paroxysmal fast activity as scalp electroencephalographic biomarkers of seizure activity and seizure onset zone
Yoo JY, Jetté N, Kwon C, Young J, Marcuse LV, Fields MC, Gaspard N, Hirsch LJ. Brief potentially ictal rhythmic discharges and paroxysmal fast activity as scalp electroencephalographic biomarkers of seizure activity and seizure onset zone. Epilepsia 2021, 62: 742-751. PMID: 33576500, DOI: 10.1111/epi.16822.Peer-Reviewed Original ResearchConceptsParoxysmal fast activitySeizure onset zoneIctal rhythmic dischargesClinical significanceElectrographic seizuresSeizure activityRhythmic dischargesFast activityOnset zoneUncontrolled seizure activityPosterior dominant rhythmSimilar clinical significancePatient demographicsElectroencephalographic biomarkerLocalizing signFocal slowingClinical historySeizure riskEEG backgroundPatientsAdult cohortDominant rhythmSeizuresDistinct entityEEG biomarkers
2020
Nonepileptic Electroencephalographic Correlates of Episodic Increases in Intracranial Pressure
Sheikh ZB, Maciel CB, Dhakar MB, Hirsch LJ, Gilmore EJ. Nonepileptic Electroencephalographic Correlates of Episodic Increases in Intracranial Pressure. Journal Of Clinical Neurophysiology 2020, 39: 149-158. PMID: 32701765, DOI: 10.1097/wnp.0000000000000750.Peer-Reviewed Original Research
2019
Continuous EEG Findings in Autoimmune Encephalitis.
Moise AM, Karakis I, Herlopian A, Dhakar M, Hirsch LJ, Cotsonis G, LaRoche S, Cabrera Kang CM, Westover B, Rodriguez A. Continuous EEG Findings in Autoimmune Encephalitis. Journal Of Clinical Neurophysiology 2019, 38: 124-129. PMID: 31800465, PMCID: PMC7263965, DOI: 10.1097/wnp.0000000000000654.Peer-Reviewed Original ResearchConceptsNew-onset refractory status epilepticusRefractory status epilepticusRhythmic delta activityGeneralized rhythmic delta activityAutoimmune encephalitisStatus epilepticusDelta activityPoor outcomeAE subtypeFast activityAntibody-negative autoimmune encephalitisN-methyl-D-aspartate receptorsDefinite limbic encephalitisExtreme delta brushMulticenter retrospective reviewNew-onset seizuresContinuous EEG monitoringGlutamic acid decarboxylaseVoltage-gated potassium channelsLimbic encephalitisRetrospective reviewAE patientsElectrographic seizuresDelta brushEEG findings
2003
Tonic–Absence Seizures: An Underrecognized Seizure Type
Shih TT, Hirsch LJ. Tonic–Absence Seizures: An Underrecognized Seizure Type. Epilepsia 2003, 44: 461-465. PMID: 12614405, DOI: 10.1046/j.1528-1157.2003.39602.x.Peer-Reviewed Original ResearchConceptsSymptomatic generalized epilepsySeizure typesTonic seizuresGeneralized epilepsyAbsence seizuresMultiple seizure typesParoxysmal fast activityEpilepsy monitoring unitSlow spikeElectroclinical patternClinical patternStatic encephalopathyClinical correlatesClinical correlationTonic activityInternational LeagueFast activitySeizuresNormal cognitionPatientsEpilepsy diagnosisEpilepsyGPFAMonitoring unitEncephalopathy