P2-02-01: A Novel Inflammatory Breast Cancer-Specific Oncogene, Tazarotene-Induced Gene 1, Promotes Tumorigenicity and Invasiveness through the Receptor Tyrosine Kinase Axl.
Wang X, Saso H, Iwamoto T, Pusztai L, Gong Y, Woodward W, Reuben J, Hortobagyi G, Ueno N. P2-02-01: A Novel Inflammatory Breast Cancer-Specific Oncogene, Tazarotene-Induced Gene 1, Promotes Tumorigenicity and Invasiveness through the Receptor Tyrosine Kinase Axl. Cancer Research 2011, 71: p2-02-01-p2-02-01. DOI: 10.1158/0008-5472.sabcs11-p2-02-01.Peer-Reviewed Original ResearchInflammatory breast cancerReceptor tyrosine kinase AXLTIG1 expressionTyrosine kinase AXLBreast cancerSUM149 cellsTumor growthEffective standard therapyNon-IBC cell linesPrognosis of patientsTreatment of patientsMammary fat padMatrix metalloproteinase-9Athymic nude miceIBC cell linesCell linesIBC cellsStandard therapyGene 1 expressionMolecular mechanismsDownregulation of expressionAxl expressionClinical subtypesMetalloproteinase-9Malignant process