Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells
Ranjan K, Waghela BN, Vaidya FU, Pathak C. Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells. International Journal Of Molecular Sciences 2020, 21: 6890. PMID: 32961826, PMCID: PMC7555701, DOI: 10.3390/ijms21186890.Peer-Reviewed Original ResearchConceptsFADD proteinCancer cellsAnti-apoptotic genesCaveolar pathwayDeath domainCellular pathwaysCancer cell proliferationCytosolic expressionFADD expressionCell deathApoptosis inducersInduces ApoptosisExpression of FasProteinCell proliferationApoptosisNF-κB activationSimultaneous regulationInflammatory signalingExpressionCellsNLRP3 inflammasome primingRegulationPathwayInflammasome primingIntestinal Immune Homeostasis and Inflammatory Bowel Disease: A Perspective on Intracellular Response Mechanisms
Ranjan K. Intestinal Immune Homeostasis and Inflammatory Bowel Disease: A Perspective on Intracellular Response Mechanisms. Gastrointestinal Disorders 2020, 2: 24. DOI: 10.3390/gidisord2030024.Peer-Reviewed Original ResearchInflammatory bowel diseaseIntestinal epithelial cellsIntestinal immune homeostasisBowel diseaseImmune homeostasisMyeloid cellsPeripheral myeloid cellsChronic inflammatory conditionsGut-resident microbesUnfolded protein responseInflammatory conditionsIntestinal homeostasisSusceptible individualsHomeostatic environmentChronic stressIntracellular mechanismsOxidative stressEpithelial cellsEndoplasmic reticulumDiseaseHomeostasisResident microbesProtein responseCellsCellular stress