2018
Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child Maltreatment
Bouvette-Turcot A, Meaney M, O’Donnell K. Epigenetics and Early Life Adversity: Current Evidence and Considerations for Epigenetic Studies in the Context of Child Maltreatment. Child Maltreatment Solutions Network 2018, 89-119. DOI: 10.1007/978-3-319-72589-5_7.Peer-Reviewed Original ResearchMental healthEarly adversityEarly life adversityLater mental healthEarly childhood adversityLater riskClinical studiesPreclinical modelsCurrent evidenceMental disordersChildhood adversityLife adversityPutative mechanismsNeural developmentDNA methylationEarly social environmentChild maltreatmentEarly environmentHealthAdversityEpigenetic mechanisms
2016
The Drosophila foraging gene human orthologue PRKG1 predicts individual differences in the effects of early adversity on maternal sensitivity
Sokolowski HM, Vasquez OE, Unternaehrer E, Sokolowski DJ, Biergans SD, Atkinson L, Gonzalez A, Silveira PP, Levitan R, O’Donnell K, Steiner M, Kennedy J, Meaney MJ, Fleming AS, Sokolowski MB, teams O. The Drosophila foraging gene human orthologue PRKG1 predicts individual differences in the effects of early adversity on maternal sensitivity. Cognitive Development 2016, 42: 62-73. PMID: 28827895, PMCID: PMC5562168, DOI: 10.1016/j.cogdev.2016.11.001.Peer-Reviewed Original ResearchGenetic variationCGMP-dependent protein kinaseAdult fruit fliesForaging (for) geneSocial insectsFruit flyProtein kinaseDrosophilaGene-environment interactionsGenesAllelesInsectsEarly environmentKinasePRKG1GeneticsFliesAdult individual differencesSelf-reported childhood adversityVariationC alleleMaternal adversityAssociatesEarly life adversityRs2043556