2024
CYP2C gene polymorphisms in North African populations
Messaoudi M, Pakstis A, Boussetta S, Ben Ammar Elgaaied A, Kidd K, Cherni L. CYP2C gene polymorphisms in North African populations. Molecular Biology Reports 2024, 51: 1145. PMID: 39532754, DOI: 10.1007/s11033-024-10093-8.Peer-Reviewed Original ResearchConceptsNorth African populationsCYP2C genesHuman CYP2C genesSuperfamily of genesAfrican populationsRegulatory regionsIntronic SNPGenetic variationHaplotype frequenciesChromosome 10Pharmacogenetic markersFunctional consequencesGenesResponse to medical treatmentSNPsTunisian populationCYP2C9Drug metabolismForeign chemicalsCYP2C19North AfricansBackgroundCytochrome P450Clinically useful drugsGene polymorphismsPrincipal component analysis
1995
Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome
Gelernter J, Rao P, Pauls D, Hamblin M, Sibley D, Kidd K. Assignment of the 5HT7 receptor gene (HTR7) to chromosome 10q and exclusion of genetic linkage with tourette syndrome. Genomics 1995, 26: 207-209. PMID: 7601444, DOI: 10.1016/0888-7543(95)80202-w.Peer-Reviewed Original ResearchConceptsGenetic linkageSomatic cell hybridsInteresting candidate genesPairwise linkage analysisCell hybridsNovel serotonin receptorCandidate genesChromosome 10Linkage analysisSouthern blotGenesExtended pedigreesLOD scoreReceptor geneLociGenetic polymorphismsHTR7PolymorphismReceptorsLIPED computer programDNALinkageHybridizationNeuropsychiatric disordersPedigree
1993
Physical and Genetic Maps for Chromosome 10
Lichter J, Difilippantonio M, Pakstis A, Goodfellow P, Ward D, Kidd K. Physical and Genetic Maps for Chromosome 10. Genomics 1993, 16: 320-324. PMID: 8314570, DOI: 10.1006/geno.1993.1192.Peer-Reviewed Original ResearchConceptsChromosome 10Physical mapOrder of lociGenetic mapLinkage mapGenetic distanceFemale mapGenetic linkage studiesMetaphase chromosomesPolymorphic lociNew lociQ armLociFractional lengthCentromeresLinkage studiesFishPhysical distanceRecombinationCentimorgansChromosomesDistance estimatesFemalesMalesFluorescence
1992
A high-resolution meiotic mapping panel for the pericentromeric region of chromosome 10
Lichter J, Wu J, Miller D, Goodfellow P, Kidd K. A high-resolution meiotic mapping panel for the pericentromeric region of chromosome 10. Genomics 1992, 13: 607-612. PMID: 1353475, DOI: 10.1016/0888-7543(92)90131-b.Peer-Reviewed Original ResearchLocalization of the gene for MEN 2A.
Lichter J, Difilippantonio M, Wu J, Miller D, Ward D, Goodfellow P, Kidd K. Localization of the gene for MEN 2A. Henry Ford Hospital Medical Journal 1992, 40: 199-204. PMID: 1362405.Peer-Reviewed Original ResearchConceptsGene mapping techniquesYeast artificial chromosomesMapping panelPericentromeric regionArtificial chromosomesGenetic linkage studiesChromosome 10GenesSitu hybridizationLinkage studiesChromosomesMBMultiple endocrine neoplasia type 2A syndromeDNAHybridizationRegionConsistent orderSmall regionLocalizationFluorescenceMarkers
1990
Genetic and physical mapping and population studies of a fibronectin receptor β-subunit-like sequence on human chromosome 19
Giuffra L, Lichter P, Wu J, Kennedy J, Pakstis A, Rogers J, Kidd J, Harley H, Jenkins T, Ward D, Kidd K. Genetic and physical mapping and population studies of a fibronectin receptor β-subunit-like sequence on human chromosome 19. Genomics 1990, 8: 340-346. PMID: 1979054, DOI: 10.1016/0888-7543(90)90291-2.Peer-Reviewed Original ResearchConceptsChromosome 19Human chromosome 19Chromosome 10 (PTEN) geneHuman fibronectin receptorChromosome 10 markersInsertion of partDifferent polymorphic lociPericentromeric regionCDNA clonesPhysical mappingPolymorphic lociChromosome 10Dominant polymorphismBeta subunitLinkage analysisShort armFibronectin receptorSitu hybridizationCodominant systemsGenesSecond polymorphismReceptor βPolymorphismCDNALoci
1989
The mapping of the locus for multiple endocrine neoplasia type 2A by linkage with chromosome 10 markers.
Simpson N, Kidd K. The mapping of the locus for multiple endocrine neoplasia type 2A by linkage with chromosome 10 markers. Hormone And Metabolic Research. Supplement Series 1989, 21: 5-9. PMID: 2572529.Peer-Reviewed Original ResearchConceptsDisease locusInterstitial retinol-binding proteinChromosome 10 markersTest of linkageChromosome 10Disease genesDeletion siteChromosome 20Additional family dataBinding proteinLociGenesExclusion of linkageSitu hybridizationD10S5Ultimate identificationRetinol-binding proteinType 2AMultiple endocrine neoplasia type 2AGenomeMarkersFamily dataLinkageProteinHybridization
1988
A linkage group of five DNA markers on human chromosome 10
Farrer L, Castiglione C, Kidd J, Myers S, Carson N, Simpson N, Kidd K. A linkage group of five DNA markers on human chromosome 10. Genomics 1988, 3: 72-77. PMID: 2906045, DOI: 10.1016/0888-7543(88)90162-0.Peer-Reviewed Original ResearchConceptsLinkage groupsDNA markersChromosome 10Recombination frequencySex-specific recombination frequenciesAccurate genetic mapHuman chromosome 10Three-locus analysisLong armChromosome 10 markersGenetic mapLinkage mapPericentric regionsMarker lociMap intervalPrevious localizationLinkage analysisProximal regionLociLarge pedigreeType 2APedigreeMultiple endocrine neoplasia type 2AD10S5MarkersD10S20, a previously unmapped RFLP (OS-3), is located on 10q near D10S4
Miki T, Nishisho I, Tateishi H, Chen Y, Kidd J, Wu J, Pravtcheva D, Pakstis A, Takai S, Ruddle F, Kidd K. D10S20, a previously unmapped RFLP (OS-3), is located on 10q near D10S4. Genomics 1988, 3: 78-81. PMID: 2906046, DOI: 10.1016/0888-7543(88)90163-2.Peer-Reviewed Original ResearchConceptsSomatic cell hybrid DNAsCell hybrid DNAsComparative mapping studiesTaqI RFLPMouse genomic DNASouthern blot analysisCM distalHybrid DNAChromosome 10Genomic DNARsaI RFLPGenetic linkageStrong linkage disequilibriumHuman cloneLinkage disequilibriumLong armBlot analysisRFLPMapping studiesLociDNAClonesBanIIDisequilibriumProbe