Atypical small acinar proliferation (ASAP): Is a repeat biopsy necessary ASAP? A multi-institutional review
Leone A, Gershman B, Rotker K, Butler C, Fantasia J, Miller A, Afiadata A, Amin A, Zhou A, Jiang Z, Sebo T, Mega A, Schiff S, Pareek G, Golijanin D, Yates J, Karnes RJ, Renzulli J. Atypical small acinar proliferation (ASAP): Is a repeat biopsy necessary ASAP? A multi-institutional review. Prostate Cancer And Prostatic Diseases 2015, 19: 68-71. PMID: 26857145, DOI: 10.1038/pcan.2015.52.Peer-Reviewed Original ResearchConceptsAtypical small acinar proliferationHigh-grade prostate cancerImmediate repeat biopsySmall acinar proliferationMulti-institutional reviewRepeat biopsySubsequent prostate cancerProstate cancerAcinar proliferationInitial diagnosisProstate biopsyRetrospective multi-institutional reviewAbnormal digital rectal examTransrectal ultrasound-guided biopsyPre-biopsy PSAHigh-grade diseaseDigital rectal examUltrasound-guided biopsyUnderwent repeat biopsyMajority of menElevated PSAGleason 7Clinicopathologic featuresRectal examHigher PSAAtypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer
Leone A, Rotker K, Butler C, Mega A, Li J, Amin A, Schiff SF, Pareek G, Golijanin D, Renzulli JF. Atypical Small Acinar Proliferation: Repeat Biopsy and Detection of High Grade Prostate Cancer. Prostate Cancer 2015, 2015: 810159. PMID: 26451257, PMCID: PMC4584238, DOI: 10.1155/2015/810159.Peer-Reviewed Original ResearchAtypical small acinar proliferationRisk prostate cancerHigh-risk prostate cancerRepeat biopsyProstate cancerProstate biopsyDiagnosis of ASAPIntermediate-risk prostate cancerHigh-grade prostate cancerSubsequent prostate biopsySmall acinar proliferationPatients of patientsMulti-institutional cohortSubsequent prostate cancerGrade prostate cancerGG 3Gleason grade 3Initial biopsyPatient characteristicsClinicopathologic featuresAcinar proliferationSubsequent diagnosisGrade 3BiopsyPatients