Sublobar Resection: A Movement from the Lung Cancer Study Group
Blasberg JD, Pass HI, Donington JS. Sublobar Resection: A Movement from the Lung Cancer Study Group. Journal Of Thoracic Oncology 2010, 5: 1583-1593. PMID: 20879185, DOI: 10.1097/jto.0b013e3181e77604.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerSublobar resectionStage IA non-small cell lung cancerStage I non-small cell lung cancerMulti-institutional phase III trialLung Cancer Study GroupPostoperative lung functionSingle-institution trialLung cancer resectionCancer Study GroupHigh-risk patientsPhase III trialsEarly-stage diseaseInvasive surgical resectionCell lung cancerHigh-risk individualsMultislice computer tomographyRate of survivalPerioperative morbidityIII trialsSurgical resectionCancer resectionLung functionOncologic effectivenessRecurrence rateReduction of Elevated Plasma Osteopontin Levels With Resection of Non–Small-Cell Lung Cancer
Blasberg JD, Pass HI, Goparaju CM, Flores RM, Lee S, Donington JS. Reduction of Elevated Plasma Osteopontin Levels With Resection of Non–Small-Cell Lung Cancer. Journal Of Clinical Oncology 2010, 28: 936-941. PMID: 20085934, PMCID: PMC2834433, DOI: 10.1200/jco.2009.25.5711.Peer-Reviewed Original ResearchConceptsEarly-stage NSCLCPlasma osteopontin levelsPlasma OPN levelsOPN levelsEnzyme-linked immunosorbent assayPlasma OPNOsteopontin levelsWeeks postsurgeryElevated Plasma Osteopontin LevelsCell lung cancer correlatesUse of thoracotomyCell lung cancerLung cancer correlatesCancer-free smokersResectable NSCLCPerioperative eventsTumor characteristicsPresurgery levelsRecurrence rateValidation cohortLung cancerCancer correlatesTherapeutic responseNSCLCIndependent cohort