2023
Effects of Ethanolic and Aqueous Extracts of Garcinia gardneriana Leaves in an In Vivo Experimental Model Induced by a Hyperlipidic Diet
do Espirito Santo B, Santana L, Kato W, de Araújo F, Tatara M, Croda J, Bogo D, de Cássia Freitas K, de Cássia Avellaneda Guimarães R, Hiane P, Pott A, de Oliveira Filiú W, de Faria B, de Oliveira Figueiredo P, do Nascimento V, Ayres F, de Oliveira Bastos P. Effects of Ethanolic and Aqueous Extracts of Garcinia gardneriana Leaves in an In Vivo Experimental Model Induced by a Hyperlipidic Diet. Nutrients 2023, 15: 1308. PMID: 36986038, PMCID: PMC10051817, DOI: 10.3390/nu15061308.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiet, High-FatEthanolFatty LiverGarciniaMicePlant ExtractsPlants, MedicinalWaterConceptsMonocyte chemoattractant protein-1 concentrationsChemoattractant protein-1 concentrationsNon-communicable chronic diseasesExperimental modelProtein-1 concentrationsHigh-fat dietHigh-density lipoproteinPossible metabolic alterationsVivo experimental modelsEffect of ethanolicAqueous extractTotal cholesterolInterleukin-10Microvesicular steatosisHepatic steatosisInsulin resistanceBlood glucoseSwiss miceHyperlipidic dietChronic diseasesDensity lipoproteinMetabolic alterationsControl groupWeight gainEthanolic extract
2022
Effects of the Seed Oil of Carica papaya Linn on Food Consumption, Adiposity, Metabolic and Inflammatory Profile of Mice Using Hyperlipidic Diet
Santana L, do Espirito Santo B, Tatara M, Negrão F, Croda J, Alves F, de Oliveira Filiú W, Cavalheiro L, Nazário C, Asato M, de Faria B, do Nascimento V, de Cássia Avellaneda Guimarães R, de Cássia Freitas K, Hiane P. Effects of the Seed Oil of Carica papaya Linn on Food Consumption, Adiposity, Metabolic and Inflammatory Profile of Mice Using Hyperlipidic Diet. Molecules 2022, 27: 6705. PMID: 36235241, PMCID: PMC9570947, DOI: 10.3390/molecules27196705.Peer-Reviewed Original ResearchConceptsOral glucose toleranceHigh-fat dietArea of adipocytesInsulin sensitivity testAcute toxicity testInflammatory profileGlucose toleranceTotal cholesterolFatty acidsIL-6Insulin resistanceMCP-1Swiss miceHyperlipidic dietLower insulinCaloric intakeMonounsaturated fatty acidsProtective effectHypoglycemic effectAdipose tissueCytokine resistanceWeight gainAdiposityFood consumptionFatty acid composition
2021
High-Fat Diet with Lyophilized Acrocomia aculeata Pulp Increases High-Density Lipoprotein-Cholesterol Levels and Inhibits Adipocyte Hypertrophy in Mice
Fernandes M, Rezende K, Inada A, de Cássia Freitas K, de Oliveira Filiú W, Cavalheiro L, Nazário C, Hiane P, Croda J, Tatara M, de Souza A, Pott A, de Cássia Avellaneda Guimarães R. High-Fat Diet with Lyophilized Acrocomia aculeata Pulp Increases High-Density Lipoprotein-Cholesterol Levels and Inhibits Adipocyte Hypertrophy in Mice. Journal Of Medicinal Food 2021, 24: 841-851. PMID: 34342510, DOI: 10.1089/jmf.2020.0124.Peer-Reviewed Original ResearchMeSH KeywordsAdipocytesAnimalsCholesterolDiet, High-FatDietary FatsFatty Acids, MonounsaturatedHypertrophyLipoproteins, HDLMiceConceptsDensity lipoprotein cholesterol levelsLipoprotein cholesterol levelsHigh-fat dietChronic noncommunicable diseasesHF diet groupSevere comorbiditiesFatty acidsCholesterol HDLAdipocyte hypertrophyFat dietSwiss miceHF dietRelevant health hazardWestern dietDiet groupHistological parametersProtective effectNoncommunicable diseasesBiochemical parametersBeneficial effectsFat depositsMiceBrazilian palmDietHealth parameters
2020
Effect of Supplementation with Hydroethanolic Extract of Campomanesia xanthocarpa (Berg.) Leaves and Two Isolated Substances from the Extract on Metabolic Parameters of Mice Fed a High-Fat Diet
Cardozo C, Inada A, Cardoso C, de Oliveira Filiú W, de Farias B, Alves F, Tatara M, Croda J, de Cássia Avellaneda Guimarães R, Hiane P, de Cássia Freitas K. Effect of Supplementation with Hydroethanolic Extract of Campomanesia xanthocarpa (Berg.) Leaves and Two Isolated Substances from the Extract on Metabolic Parameters of Mice Fed a High-Fat Diet. Molecules 2020, 25: 2693. PMID: 32531999, PMCID: PMC7321075, DOI: 10.3390/molecules25112693.Peer-Reviewed Original ResearchConceptsHigh-fat dietInterleukin-6Diet-induced obesity modelBeneficial effectsHydroethanolic extractMale Swiss miceHydroethanolic leaf extractEffect of supplementationLipid parametersMice fedAdiposity gainFat dietSwiss miceObesity modelObesity featuresMetabolic parametersFood intakeHistological parametersMetabolic disordersBody weightNutrition dietProtein expressionDietFood behaviorFurther investigation