2024
The greatest Dengue epidemic in Brazil: Surveillance, Prevention, and Control
Gurgel-Gonçalves R, de Oliveira W, Croda J. The greatest Dengue epidemic in Brazil: Surveillance, Prevention, and Control. Revista Da Sociedade Brasileira De Medicina Tropical 2024, 57: e00203-2024. PMID: 39319953, PMCID: PMC11415067, DOI: 10.1590/0037-8682-0113-2024.Peer-Reviewed Original ResearchConceptsHealth education initiativesPhase 3 clinical trialsPublic health systemMinistry of HealthIndoor residual sprayingSterile insect techniqueHealth servicesHealth systemTakeda vaccineCommunity mobilizationMultisectoral approachDengue epidemicsDengue casesEducational initiativesDengue mortalityResidual sprayingMosquito controlHome cleaningInsect techniqueAedes aegyptiPotential mosquito breeding sitesHealthVaccination coverageDengue virusVaccineBCG vaccination of healthcare workers for protection against COVID-19: 12-month outcomes from an international randomised controlled trial
Messina N, Pittet L, McDonald E, Moore C, Barry S, Bonten M, Byrne A, Campbell J, Croda J, Croda M, Dalcolmo M, de Almeida e Val F, de Oliveira R, dos Santos G, Douglas M, Gardiner K, Gwee A, Jardim B, Kollmann T, Lacerda M, Lucas M, Lynn D, Manning L, Marshall H, O’Connell A, Perrett K, Post J, Prat-Aymerich C, Rocha J, Rodriguez-Baño J, Wadia U, Warris A, Davidson A, Curtis N, Group T. BCG vaccination of healthcare workers for protection against COVID-19: 12-month outcomes from an international randomised controlled trial. Journal Of Infection 2024, 89: 106245. PMID: 39127450, PMCID: PMC11409612, DOI: 10.1016/j.jinf.2024.106245.Peer-Reviewed Original ResearchConceptsBacille Calmette-GuerinBreakthrough COVID-19Healthcare workersSevere COVID-19Risk of severe COVID-19Placebo groupSymptomatic COVID-19BCG-DenmarkRisk of symptomatic COVID-19International randomised controlled trialRandomised controlled trialsBacille Calmette-Guerin vaccineVaccination of healthcare workersHealthcare centresSARS-CoV-2 testingAsymptomatic SARS-CoV-2 infectionRandomised 1:1SARS-CoV-2 infectionCOVID-19MITT populationControlled trialsHealthcareIntradermal doseModified intentionImmunomodulatory effectsInsights into SARS-CoV-2 Surveillance among Prison Populations in Mato Grosso do Sul, Brazil, in 2022
da Silva L, Alcantara L, Fonseca V, Frias D, Zardin M, de Castro Lichs G, Esposito A, Xavier J, Fritsch H, Lima M, de Oliveira C, de Arruda L, de Mello Almeida Maziero L, Barretos E, Oshiro P, Menezes E, de Freitas Cardoso L, Lemos E, Lourenço J, de Albuquerque C, do Carmo Said R, Rosewell A, Demarchi L, Croda J, Giovanetti M, Gonçalves C. Insights into SARS-CoV-2 Surveillance among Prison Populations in Mato Grosso do Sul, Brazil, in 2022. Viruses 2024, 16: 1143. PMID: 39066305, PMCID: PMC11281713, DOI: 10.3390/v16071143.Peer-Reviewed Original ResearchConceptsNext-generation sequencingPrison populationIncarcerated populationsOvercrowded cellsGenome sequenceGenomic characteristicsPrisonGenomic surveillanceEnclosed populationMato GrossoAverage coverageIsolation protocolSARS-CoV-2RT-qPCR testSARS-CoV-2 surveillanceRT-qPCRSequenceFrequent transferEpidemiological monitoringLimited healthcare accessGenomeCellsOmicron variantSeroprevalence of Treponema pallidum infection among high-risk populations from Brazil
Queiroz J, Barbosa M, Perez E, da Silva B, de Souza G, Gonçalves C, Croda J, Simionatto S. Seroprevalence of Treponema pallidum infection among high-risk populations from Brazil. Acta Tropica 2024, 256: 107255. PMID: 38761835, DOI: 10.1016/j.actatropica.2024.107255.Peer-Reviewed Original ResearchConceptsSexually transmitted infectionsHigh-risk groupCases of syphilisFactors associated with syphilisPregnant womenHistory of sexually transmitted infectionsPublic health strategiesHealthy populationSignificant public health concernPrevent future complicationsHigh risk of infectionHigh-risk populationPublic health concernHealth strategiesParticipant demographicsCross-sectional oneRisk of infectionVulnerable populationsFuture complicationsPLHIVTreatment outcomesHealth concernHigh riskSyphilisInfectionEffect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial
dos Santos P, Messina N, de Oliveira R, da Silva P, Puga M, Dalcolmo M, dos Santos G, de Lacerda M, Jardim B, de Almeida e Val F, Curtis N, Andrews J, Croda J. Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial. The Lancet Infectious Diseases 2024, 24: 594-601. PMID: 38423021, PMCID: PMC11111441, DOI: 10.1016/s1473-3099(23)00818-6.Peer-Reviewed Original ResearchConceptsQuantiFERON-TB GoldPlacebo groupEffect of BCG vaccinationBCG vaccinationBCG groupBCG-DenmarkHealth-care workersNegative baseline resultsMonths of treatmentMycobacterium tuberculosis infectionAdult pulmonary tuberculosisQuantiFERON-TBMedian ageRandomised controlled trialsPulmonary tuberculosisNo significant differenceEfficacy outcomesTuberculosis infectionClinical trialsControlled trialsEffect of vaccinationTreatment drugsTuberculosis preventionSubstudySignificant differenceCatastrophic Floods in Rio Grande do Sul, Brazil: The Need for Public Health Responses to Potential Infectious Disease Outbreaks
Martins-Filho P, Croda J, Araújo A, Correia D, Quintans-Júnior L. Catastrophic Floods in Rio Grande do Sul, Brazil: The Need for Public Health Responses to Potential Infectious Disease Outbreaks. Revista Da Sociedade Brasileira De Medicina Tropical 2024, 57: e00603-2024. PMID: 38808800, PMCID: PMC11136508, DOI: 10.1590/0037-8682-0162-2024.Peer-Reviewed Original ResearchAdvances in the development of new vaccines for tuberculosis and Brazil’s role in the effort forward the end TB strategy
Junqueira-Kipnis A, de Cerqueira Leite L, Croda J, Chimara E, Carvalho A, Arcêncio R. Advances in the development of new vaccines for tuberculosis and Brazil’s role in the effort forward the end TB strategy. Memórias Do Instituto Oswaldo Cruz 2024, 119: e240093. PMID: 39383403, PMCID: PMC11452070, DOI: 10.1590/0074-02760240093.Peer-Reviewed Original Research
2023
Seroprevalence Of SARS-COV-2 infection in asymptomatic indigenous from the largest Brazilian periurban area
de Oliveira L, Dos Santos Barbosa M, Leite Torres A, Croda M, Oliveira da Silva B, Dos Santos P, Rossoni R, Machado L, Croda J, Maymone Gonçalves C, Marques M, da Silva Ferreira T, Sardi S, Campos G, de Almeida G, Alves Gomes M, Marchioro S, Simionatto S. Seroprevalence Of SARS-COV-2 infection in asymptomatic indigenous from the largest Brazilian periurban area. PLOS ONE 2023, 18: e0295211. PMID: 38134187, PMCID: PMC10745159, DOI: 10.1371/journal.pone.0295211.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayCoronaVac inactivated vaccinesSARS-CoV-2SARS-CoV-2 infectionEnzyme-linked immunosorbent assay methodMedian ageSARS-CoV-2 antibodiesSeroprevalence of SARS-CoV-2 antibodiesSeroprevalence of SARS-CoV-2Asymptomatic individualsRapid testSeropositivity rateBlood samplesEthnic groupsElevated seroprevalenceImmunosorbent assaySeroprevalence of SARS-CoV-2 infectionSARS-CoV-2 rapid testSeropositivityAntibodiesVulnerable ethnic groupsSeroprevalenceGenomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil
de Oliveira L, de Rezende I, Navarini V, Marchioro S, Torres A, Croda J, Croda M, Gonçalves C, Xavier J, de Castro E, Lima M, Iani F, Adelino T, Aburjaile F, Demarchi L, Taira D, Zardin M, Fonseca V, Giovanetti M, Andrews J, Alcantara L, Simionatto S. Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil. Frontiers In Public Health 2023, 11: 1195779. PMID: 37965526, PMCID: PMC10641392, DOI: 10.3389/fpubh.2023.1195779.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 lineagesIntroduction eventsCharacterization of SARS-CoV-2Nanopore sequencing platformSARS-CoV-2 positive samplesMultiple SARS-CoV-2 variantsMultiple introduction eventsPhylogenetic reconstructionPhylogenetic dataGenome sequenceSequencing platformsGenomic characterizationSARS-CoV-2Genomic surveillanceSARS-CoV-2 variantsLineagesMato GrossoMortality rateViral dynamicsIndigenous populationCo-circulationPrevalence of malesMidwestern BrazilPositive samplesIndigenous mobilizationDengue Fever Surveillance in Mato Grosso do Sul: Insights from Genomic Analysis and Implications for Public Health Strategies
de Arruda L, Giovanetti M, Fonseca V, Zardin M, de Castro Lichs G, Asato S, Esposito A, Müller M, Xavier J, Fritsch H, Lima M, de Oliveira C, Santos E, de Mello Almeida Maziero L, Frias D, Neves D, da Silva L, Barretos E, Oshiro P, Goday B, dos Santos J, Kashima S, de Albuquerque C, do Carmo Said R, Rosewell A, Demarchi L, Croda J, Alcantara L, Gonçalves C. Dengue Fever Surveillance in Mato Grosso do Sul: Insights from Genomic Analysis and Implications for Public Health Strategies. Viruses 2023, 15: 1790. PMID: 37766197, PMCID: PMC10536684, DOI: 10.3390/v15091790.Peer-Reviewed Original ResearchConceptsInforming public health actionOn-site training programDiverse viral lineagesPublic health actionPublic health strategiesMultiple introduction eventsSecretary of HealthMonitoring viral evolutionHealth strategiesHealth actionsGenome sequenceGenomic analysisDynamics of dengue virusTraining programIntroduction eventsGenomic surveillanceViral transmission patternsViral lineagesPublic healthHealthMato GrossoEpidemiological dataViral evolutionPreventive measuresSurveillance activitiesPan-American Guidelines for the treatment of SARS-CoV-2/COVID-19: a joint evidence-based guideline of the Brazilian Society of Infectious Diseases (SBI) and the Pan-American Association of Infectious Diseases (API)
Barbosa A, Chebabo A, Starling C, Pérez C, Cunha C, de Luna D, Nunes E, Zambrano G, Ferreira J, Croda J, Falavigna M, Gomes-da-Silva M, Thormann M, Cimerman S, Parahiba S, Tanni S, Bernardo W, Rodriguez-Morales A. Pan-American Guidelines for the treatment of SARS-CoV-2/COVID-19: a joint evidence-based guideline of the Brazilian Society of Infectious Diseases (SBI) and the Pan-American Association of Infectious Diseases (API). Annals Of Clinical Microbiology And Antimicrobials 2023, 22: 67. PMID: 37550690, PMCID: PMC10408214, DOI: 10.1186/s12941-023-00623-w.Peer-Reviewed Original ResearchConceptsUse of hydroxychloroquineInfectious diseasesCOVID-19Treatment of outpatientsSARS-CoV-2/COVIDSevere COVID-19Evidence-based guidelinesPan American AssociationGuideline development processLack of benefitEvidence-based medicineAdverse eventsMechanical ventilationClinical manifestationsTherapeutic optionsPharmacological treatmentCOVID-19 episodeInpatient settingAmerican guidelinesGRADE systemSystematic reviewStrong recommendationsProphylaxisOutpatientsDiseaseUnveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil
de Mello Almeida Maziero L, Giovanetti M, Fonseca V, Zardin M, de Castro Lichs G, de Rezende Romera G, Tsuha D, Frias D, Escandolhero V, Demarchi L, Castilho L, Barbosa K, Tebet D, Xavier J, Fritsch H, Lima M, de Oliveira C, Santos E, Kashima S, do Carmo Said R, Rosewell A, Croda J, Alcantara L, Gonçalves C. Unveiling the Impact of the Omicron Variant: Insights from Genomic Surveillance in Mato Grosso do Sul, Midwest Brazil. Viruses 2023, 15: 1604. PMID: 37515290, PMCID: PMC10386548, DOI: 10.3390/v15071604.Peer-Reviewed Original ResearchConceptsGenomic surveillanceWhole-genome sequencingMultiple introduction eventsGenome sequencePublic health interventionsGenomic dataGenomic monitoringIntroduction eventsPublic health responseGenomic landscapeDispersal dynamicsPhylodynamic analysesPublic health laboratoriesHealth interventionsMato GrossoHealth responseTransmissible variantsSignificant burdenCentral Public Health LaboratoryOmicron variantVariantsHealth laboratoriesSequenceMidwest region of BrazilViral strainsUse of rapid molecular TB diagnostics for incarcerated people in Brazil
Fajer E, Costa F, Pelissari D, Quijano F, de Brito A, Cunha E, Croda J, Andrews J, Walter K. Use of rapid molecular TB diagnostics for incarcerated people in Brazil. The International Journal Of Tuberculosis And Lung Disease 2023, 27: 416-418. PMID: 37143225, PMCID: PMC10171485, DOI: 10.5588/ijtld.22.0642.Peer-Reviewed Original ResearchSpread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study
Busatto C, Possuelo L, Bierhals D, de Oliveira C, de Souza M, Fanfa D, Barreto É, Schwarzbold P, Von Groll A, Portugal I, Perdigão J, Croda J, Andrews J, da Silva P, Ramis I. Spread of Mycobacterium tuberculosis in Southern Brazilian persons deprived of liberty: a molecular epidemiology study. European Journal Of Clinical Microbiology & Infectious Diseases 2023, 42: 297-304. PMID: 36701032, DOI: 10.1007/s10096-023-04546-4.Peer-Reviewed Original ResearchConceptsAnti-TB drug resistanceM. tuberculosisTB control programsCross-sectional studyM. tuberculosis strainsMolecular epidemiology studiesTB burdenLAM strainsTuberculosis strainsEpidemiology studiesDrug resistanceMycobacterium tuberculosisCentral laboratoryTranslational researchTuberculosisCommon strainControl programsPDLMolecular characterizationHaarlemImproved strategiesPersonsDelay in the diagnosis and treatment of tuberculosis in prisons in Mato Grosso do Sul, Brazil
Ribeiro C, da Silva Santos A, Tshua D, de Oliveira R, Lemos E, Bourdillon P, Laranjeira A, Gonçalves C, Andrews J, Ko A, Croda J. Delay in the diagnosis and treatment of tuberculosis in prisons in Mato Grosso do Sul, Brazil. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0015-2023. PMID: 37493729, PMCID: PMC10367220, DOI: 10.1590/0037-8682-0015-2023.Peer-Reviewed Original ResearchConceptsSymptom onsetFirst symptomsLargest male prisonPrison medical recordsTB case dataRetrospective cohort studyPulmonary TB casesYear of diagnosisStart of treatmentTreatment of TBTreatment of tuberculosisNumber of symptomsAverage timePercentage of cureProvider delayTB casesCohort studyTreatment initiationHIV statusSmoking statusTuberculosis casesTB transmissionFirst consultationPatient delayMedical recordsResearch, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB
Arcêncio R, Chimara E, Lapa e Silva J, Croda J, Carvalho A. Research, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0518-2023. PMID: 38055542, PMCID: PMC10691762, DOI: 10.1590/0037-8682-0518-2023.Peer-Reviewed Original Research
2022
Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil
Ranzani OT, Hitchings MDT, de Melo RL, de França GVA, Fernandes CFR, Lind ML, Torres MSS, Tsuha DH, David LCS, Said RFC, Almiron M, de Oliveira RD, Cummings DAT, Dean NE, Andrews JR, Ko AI, Croda J. Effectiveness of an inactivated Covid-19 vaccine with homologous and heterologous boosters against Omicron in Brazil. Nature Communications 2022, 13: 5536. PMID: 36202800, PMCID: PMC9537178, DOI: 10.1038/s41467-022-33169-0.Peer-Reviewed Original ResearchHTLV infection in Brazil’s second-largest indigenous reserve
Amianti C, Bandeira L, Cesar G, Weis-Torres S, Tanaka T, Machado I, Gonçalves C, Simionatto S, Schnaufer E, Freitas F, Vallinoto A, Croda J, Motta-Castro A. HTLV infection in Brazil’s second-largest indigenous reserve. Scientific Reports 2022, 12: 16701. PMID: 36202887, PMCID: PMC9537150, DOI: 10.1038/s41598-022-21086-7.Peer-Reviewed Original ResearchConceptsHTLV infectionHTLV-1HTLV-2HTLV-1-associated myelopathyAdult T-cell leukemia/lymphomaHuman T-lymphotropic virus 1T-cell leukemia/lymphomaChronic inflammatory neurological diseaseHTLV-1 prevalenceInflammatory neurological diseasesHTLV-2 infectionAggressive malignant diseaseLeukemia/lymphomaEnzyme-linked immunosorbentMedian agePregnant populationMalignant diseaseBlood donorsStudy populationDrug usersNeurological diseasesCosmopolitan subtypeWestern blotSerum samplesDiseaseGenomic epidemiology of the SARS-CoV-2 epidemic in Brazil
Giovanetti M, Slavov S, Fonseca V, Wilkinson E, Tegally H, Patané J, Viala V, San E, Rodrigues E, Santos E, Aburjaile F, Xavier J, Fritsch H, Adelino T, Pereira F, Leal A, Iani F, de Carvalho Pereira G, Vazquez C, Sanabria G, Oliveira E, Demarchi L, Croda J, dos Santos Bezerra R, Paola Oliveira de Lima L, Martins A, Renata dos Santos Barros C, Marqueze E, de Souza Todao Bernardino J, Moretti D, Brassaloti R, de Lello Rocha Campos Cassano R, Mariani P, Kitajima J, Santos B, Proto-Siqueira R, Cantarelli V, Tosta S, Nardy V, Reboredo de Oliveira da Silva L, Gómez M, Lima J, Ribeiro A, Guimarães N, Watanabe L, Barbosa Da Silva L, da Silva Ferreira R, da Penha M, Ortega M, de la Fuente A, Villalba S, Torales J, Gamarra M, Aquino C, Figueredo G, Fava W, Motta-Castro A, Venturini J, do Vale Leone de Oliveira S, Gonçalves C, do Carmo Debur Rossa M, Becker G, Giacomini M, Marques N, Riediger I, Raboni S, Mattoso G, Cataneo A, Zanluca C, Duarte dos Santos C, Assato P, Allan da Silva da Costa F, Poleti M, Lesbon J, Mattos E, Banho C, Sacchetto L, Moraes M, Grotto R, Souza-Neto J, Nogueira M, Fukumasu H, Coutinho L, Calado R, Neto R, Bispo de Filippis A, Venancio da Cunha R, Freitas C, Peterka C, de Fátima Rangel Fernandes C, Navegantes W, do Carmo Said R, Campelo de A e Melo C, Almiron M, Lourenço J, de Oliveira T, Holmes E, Haddad R, Sampaio S, Elias M, Kashima S, Junior de Alcantara L, Covas D. Genomic epidemiology of the SARS-CoV-2 epidemic in Brazil. Nature Microbiology 2022, 7: 1490-1500. PMID: 35982313, PMCID: PMC9417986, DOI: 10.1038/s41564-022-01191-z.Peer-Reviewed Original ResearchConceptsVariants of concernSARS-CoV-2 variantsLocal transmission clustersSARS-CoV-2 epidemicSARS-CoV-2COVID-19 casesTransmission clustersVirus transmission dynamicsSustained transmissionMultiple importationsMultiple viral lineagesGenomic epidemiologyGenomic surveillanceReal-time spreadTransmission dynamicsEpidemicViral lineagesHigher numberPandemicRestriction measuresEpidemiologyVariantsCoronavirus disease COVID-19 pandemic and the Declaration of Public Health Emergency in Brazil: administrative and epidemiological aspects
de Oliveira W, de Góes Cavalcanti L, Croda J. Coronavirus disease COVID-19 pandemic and the Declaration of Public Health Emergency in Brazil: administrative and epidemiological aspects. Revista Da Sociedade Brasileira De Medicina Tropical 2022, 55: e0227-2022. PMID: 35613222, PMCID: PMC9131777, DOI: 10.1590/0037-8682-0227-2022.Peer-Reviewed Original Research