1997
alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity.
Peng SL, McNiff JM, Madaio MP, Ma J, Owen MJ, Flavell RA, Hayday AC, Craft J. alpha beta T cell regulation and CD40 ligand dependence in murine systemic autoimmunity. The Journal Of Immunology 1997, 158: 2464-70. PMID: 9036998, DOI: 10.4049/jimmunol.158.5.2464.Peer-Reviewed Original ResearchConceptsAlpha beta T cellsBeta T cellsGamma delta T cellsAutoimmune skin diseaseDelta T cellsT cellsRenal diseaseSystemic autoimmunitySkin diseasesAutoantibody productionMurine lupusCutaneous diseaseT cell-dependent mechanismAlpha betaHigh-titer autoantibodiesLupus-prone miceSevere renal diseaseCell-dependent mechanismT cell regulationCutaneous lesionsCD40 ligandAutoantibodiesAutoimmunityLow titersLpr animals
1996
Systemic autoimmunity in LGJ mice
Peng S, Madaio M, Craft J. Systemic autoimmunity in LGJ mice. Immunology Letters 1996, 53: 153-155. PMID: 9024995, DOI: 10.1016/s0165-2478(96)02616-8.Peer-Reviewed Original ResearchConceptsLG/J miceJ miceAnalysis of autoimmunityEnd-organ diseaseNon-diseased animalsAntinuclear antibodiesInterstitial nephritisLupus erythematosusRenal diseaseRheumatoid factorCutaneous diseaseSystemic autoimmunityMurine modelControl animalsJ strainJ backgroundAutoimmunityDiseaseMiceAutoantibodiesUseful modelAnimalsErythematosusPerivasculitisGlomerulonephritis
1993
Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III.
Hirakata M, Okano Y, Pati U, Suwa A, Medsger TA, Hardin JA, Craft J. Identification of autoantibodies to RNA polymerase II. Occurrence in systemic sclerosis and association with autoantibodies to RNA polymerases I and III. Journal Of Clinical Investigation 1993, 91: 2665-2672. PMID: 8390487, PMCID: PMC443330, DOI: 10.1172/jci116505.Peer-Reviewed Original ResearchConceptsSystemic sclerosisII antibodiesAnti-RNA polymerase II antibodiesLimited cutaneous diseaseConnective tissue diseaseIdentification of autoantibodiesSera of patientsIndirect immunofluorescence studiesHuman serumTissue diseaseCutaneous diseaseNormal controlsAutoantibodiesSclerosisPatientsHuman antibodiesRNA polymerase IIClinical perspectiveMonoclonal antibodiesAntibodiesSerumRNA polymerase IImmunofluorescence studiesImmunodepletion studiesFurther studies