2013
Transfer of antigen from human B cells to dendritic cells
Harvey BP, Raycroft MT, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ. Transfer of antigen from human B cells to dendritic cells. Molecular Immunology 2013, 58: 56-65. PMID: 24309484, PMCID: PMC4234097, DOI: 10.1016/j.molimm.2013.10.013.Peer-Reviewed Original Research
2008
Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors
Harvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ. Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors. The Journal Of Immunology 2008, 181: 4043-4051. PMID: 18768860, PMCID: PMC2701691, DOI: 10.4049/jimmunol.181.6.4043.Peer-Reviewed Original ResearchConceptsHuman B lymphocytesB lymphocytesImmune responseB cellsB cell-directed therapiesChronic autoimmune responseCell-directed therapiesScavenger receptor ASpecific B cellsClass A Scavenger ReceptorB cell APCDendritic cellsAntigen transferAutoimmune responseProfessional APCsEfficient APCsAntigen presentationTransfer of AgSpecific AgReceptor AScavenger receptorsMacrophagesLymphocytesAPCReceptorsScavenger receptor type AI mediates antigen transfer from human B cells to other APCs
Harvey B, Quan T, Roman R, Rudenga B, Craft J, Mamula M. Scavenger receptor type AI mediates antigen transfer from human B cells to other APCs. The FASEB Journal 2008, 22: 1068.14-1068.14. DOI: 10.1096/fasebj.22.1_supplement.1068.14.Peer-Reviewed Original ResearchAntigen-presenting cellsProfessional antigen-presenting cellsB cellsAntigen transferTreatment of lupusInduction of autoimmunityTransfer of antigenUptake of antigensSpecific B cell receptorsNovel therapeutic targetMonocytic cell line THP-1Ig transgenic miceHuman monocytic cell line THP-1Cell line THP-1Human B cellsB cell receptorDendritic cellsChronic autoimmunityArthritis FoundationImmune responseAntigen traffickingB cell deathCritical antigensTherapeutic targetSpecific antigen