2024
Perioperative inpatient falls for anterior cervical discectomy and fusion patients are on the rise: Risk factors associated with this “never event”
Seddio A, Jabbouri S, Gouzoulis M, Vasudevan R, Halperin S, Varthi A, Rubio D, Grauer J. Perioperative inpatient falls for anterior cervical discectomy and fusion patients are on the rise: Risk factors associated with this “never event”. The Spine Journal 2024 PMID: 39631462, DOI: 10.1016/j.spinee.2024.11.018.Peer-Reviewed Original ResearchInpatient fallsLength of stayMultivariate logistic regressionAnterior cervical discectomyInpatient ACDFElixhauser Comorbidity IndexMultidisciplinary fall prevention programAnnual incidenceRisk factorsInpatient fall preventionFall prevention programsLogistic regressionNational sample of patientsCervical discectomyNational Quality ForumSocioeconomically disadvantaged patientsHistory of dementiaUnderweight body mass indexACDF patientsObese BMI >Posterior cervical proceduresBody mass indexMulti-level ACDFAdult patientsQuality ForumImproved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: A promising new addition to preoperative optimization. JSES International 2024 DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomesRisk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty
Jayaram R, Day W, Gouzoulis M, Zhu J, Grauer J, Rubin L. Risk Factors for Perioperative Nerve Injury Related to Total Hip Arthroplasty. Arthroplasty Today 2024, 28: 101440. PMID: 39139361, PMCID: PMC11320433, DOI: 10.1016/j.artd.2024.101440.Peer-Reviewed Original ResearchBody mass indexNerve injuryElixhauser Comorbidity IndexRisk factorsMultivariate analysisOdds ratioRisk of nerve injuryTotal hip arthroplastyRevision proceduresObese BMI statusUnderweight body mass indexDecreased odds ratioPatient ageSurgery typeRisk stratificationAdverse eventsBMI statusMass indexFemale sexAdverse outcomesComorbidity indexDecreased riskPatient counselingHip arthroplastyNerveFemale Patients Undergoing Latarjet Surgery Show Similar 2-Year Secondary Surgery Rates but Greater Risk of Emergency Department Visits Compared With a Matched Cohort of Male Patients
Gillinov S, Islam W, Modrak M, Mahatme R, Wilhelm C, McLaughlin W, Surucu S, Moran J, Lee M, Grauer J, Jimenez A. Female Patients Undergoing Latarjet Surgery Show Similar 2-Year Secondary Surgery Rates but Greater Risk of Emergency Department Visits Compared With a Matched Cohort of Male Patients. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2024, 40: 2645-2651.e1. PMID: 38513877, DOI: 10.1016/j.arthro.2024.02.043.Peer-Reviewed Original ResearchSecondary surgery rateElixhauser Comorbidity Index scoreCohort of male patientsBody mass indexElixhauser Comorbidity IndexSurgery ratesRecurrent shoulder instabilityFemale patientsMale patientsLatarjet procedureFemale sexShoulder instabilityED visitsIncidence of secondary surgeryEmergency departmentAssociated with female sexInternational Classification of Diseases (ICD)-10 diagnosisNational administrative claims databaseKaplan-Meier analysisAssociated with OREvaluate sex-based differencesTreatment of recurrent shoulder instabilityPostoperative emergency departmentMultivariate logistic regressionAdministrative claims database
2023
Medicaid Insurance Is Associated With More Complications and Emergency Department Visits but Equivalent 5-Year Secondary Surgery Rate After Primary Hip Arthroscopy
Gillinov S, Kim D, Islam W, Lee M, Moran J, Fong S, Mahatme R, McLaughlin W, Maldonado D, Medvecky M, Grauer J, Jimenez A. Medicaid Insurance Is Associated With More Complications and Emergency Department Visits but Equivalent 5-Year Secondary Surgery Rate After Primary Hip Arthroscopy. Arthroscopy The Journal Of Arthroscopic And Related Surgery 2023, 40: 1117-1125. PMID: 37597701, DOI: 10.1016/j.arthro.2023.08.011.Peer-Reviewed Original ResearchPrimary hip arthroscopyFemoroacetabular impingement syndromeEmergency department visitsSecondary surgery rateED visitsMedicaid patientsHip arthroscopyDepartment visitsSurgery ratesSecondary surgeryLabral tearsLarge national database studyTenth Revision diagnosis codesNational database studyFive-year ratesElixhauser Comorbidity IndexKaplan-Meier analysisRevision diagnosis codesBody mass indexMultivariate logistic regressionTotal hip arthroplastyLarge national databaseComorbidity indexPostoperative complicationsAdverse eventsRisk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients
Ratnasamy P, Rudisill K, Oghenesume O, Riedel M, Grauer J. Risk of Contralateral Hip Fracture Following Initial Hip Fracture Among Geriatric Fragility Fracture Patients. JAAOS Global Research And Reviews 2023, 7: e23.00001. PMID: 37428152, PMCID: PMC10332831, DOI: 10.5435/jaaosglobal-d-23-00001.Peer-Reviewed Original ResearchConceptsContralateral hip fractureInitial hip fractureKaplan-Meier survival analysisGeriatric hip fracturesHip fractureSurvival analysisFragility fracture patientsIndex hip fractureHip fracture fixationKaplan-Meier analysisBody mass indexMultivariate logistic regressionFracture patientsContralateral fractureIndependent predictorsGeriatric patientsHigh morbidityMass indexPatient mortalityFemale sexNational cohortRisk factorsFracture fixationMultivariate analysisLogistic regressionPostoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection
Mookerjee V, Kammien A, Prassinos A, Grauer J, Butler P. Postoperative Antibiotics Following Reduction Mammaplasty Does Not Reduce Rates of Surgical Site Infection. Aesthetic Surgery Journal 2023, 43: np494-np499. PMID: 36788713, DOI: 10.1093/asj/sjad030.Peer-Reviewed Original ResearchConceptsRate of SSISurgical site infectionBody mass indexReduction mammaplasty patientsPostoperative antibioticsPerioperative antibioticsED visitsSSI ratesSite infectionObese populationReduction mammaplastyPostoperative antibiotic useElixhauser Comorbidity IndexEmergency department visitsSubgroup of patientsPostoperative prescriptionComorbidity indexObese patientsPostoperative courseDepartment visitsMass indexAntibiotic utilizationSubgroup analysisAntibiotic useHigh risk
2022
Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis
Gillinov SM, Joo PY, Zhu JR, Moran J, Rubin LE, Grauer JN. Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 1047-1053. PMID: 35947825, PMCID: PMC9588560, DOI: 10.5435/jaaos-d-22-00150.Peer-Reviewed Original ResearchConceptsPrimary total hip arthroplastyTotal hip arthroplastyElixhauser Comorbidity IndexBody mass indexComorbidity indexMass indexHip dislocationRevision surgeryRisk factorsHip arthroplastyIndex total hip arthroplastyHigher Elixhauser comorbidity indexPrimary THA patientsFirst-time dislocationCumulative incidenceMost patientsPostoperative dataTHA patientsRecurrent episodesControl subjectsFemale sexLarge cohortPatientsMultivariate analysisYounger ageIncidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients
Gillinov SM, Fosam A, Burroughs PJ, Schneble CA, McLaughlin WM, Moran J, Jimenez AE, Grauer JN, Medvecky MJ. Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients. The American Journal Of Sports Medicine 2022, 50: 2893-2899. PMID: 35916771, DOI: 10.1177/03635465221111115.Peer-Reviewed Original ResearchConceptsBony realignment proceduresAutologous chondrocyte implantationBody mass indexPrimary Autologous Chondrocyte ImplantationRevision surgeryRisk factorsRealignment proceduresPostoperative yearKnee arthroplastyFemale sexChondrocyte implantationECI scoresElixhauser comorbidity index scoreChondral defectsComorbidity Index scoreKaplan-Meier analysisLarge national cohortUnicompartmental knee arthroplastyTotal knee arthroplastyOsteochondral allograft transplantationLevel of evidenceOsteochondral autograft transferArticular cartilage proceduresFull-thickness chondral defectsChondral proceduresJump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard?
Rankin KA, Freedman IG, Moore HG, Halperin SJ, Rubin LE, Grauer JN. Jump in Elective Total Hip and Knee Arthroplasty Numbers at Age 65 Years: Evidence for Moral Hazard? JAAOS Global Research And Reviews 2022, 6: e22.00035. PMID: 35315795, PMCID: PMC8942773, DOI: 10.5435/jaaosglobal-d-22-00035.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyAge 65 yearsNational Surgical Quality Improvement Program databaseIncidence of TKAElective total knee arthroplastyQuality Improvement Program databaseLower body mass indexElective total hipPostoperative adverse eventsPreoperative American SocietyImprovement Program databaseLower functional statusBody mass indexNon-Hispanic whitesNumber of proceduresAnesthesiologists classPreoperative characteristicsOlder patientsAdverse eventsTHA patientsMass indexTotal hipFunctional statusKnee arthroplastyUnderweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion
Ottesen TD, Galivanche AR, Greene JD, Malpani R, Varthi AG, Grauer JN. Underweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion. The Spine Journal 2022, 22: 1139-1148. PMID: 35231643, DOI: 10.1016/j.spinee.2022.02.012.Peer-Reviewed Original ResearchConceptsBody mass indexNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseAnterior lumbar interbody fusionObese class 1Improvement Program databaseClass 2 patientsAdverse eventsUnderweight patientsBMI categoriesAdverse outcomesBMI spectrumInterbody fusionProgram databaseTwo-level anterior lumbar interbody fusionSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisThirty-day adverse eventsWorld Health Organization categoriesBody mass index groupsPostoperative adverse eventsRetrospective cohort studyPerioperative adverse eventsNormal-weight subjectsPost-operative infection
2021
Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery.
Kebaish KJ, Galivanche AR, Varthi AG, Ottesen TD, Rubin LE, Grauer JN. Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery. Orthopedics 2021, 44: 172-179. PMID: 34039214, DOI: 10.3928/01477447-20210416-01.Peer-Reviewed Original ResearchConceptsLong-term corticosteroid usePosterior lumbar spine surgeryPosterior lumbar surgeryLumbar spine surgeryPerioperative adverse outcomesCorticosteroid useAdverse eventsLumbar surgerySpine surgeryPropensity matchingAdverse outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsEffect of immunosuppressionImprovement Program databaseLong-term corticosteroidsSerious adverse eventsBody mass indexMultiple surgical specialtiesAnesthesiologists classComparable patientsPerioperative outcomesSurgical factorsMore patientsUnderweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty.
Ottesen TD, Hsiang WR, Malpani R, Nicholson AD, Varthi AG, Rubin LE, Grauer JN. Underweight Patients Are the Greatest Risk Body Mass Index Group for 30-Day Perioperative Adverse Events After Total Shoulder Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: e132-e142. PMID: 32568997, DOI: 10.5435/jaaos-d-20-00049.Peer-Reviewed Original ResearchConceptsBody mass indexPerioperative adverse eventsTotal shoulder arthroplastyNormal weight patientsAdverse eventsTSA patientsBMI categoriesUnderweight patientsShoulder arthroplastyNational Surgical Quality Improvement Program databaseElective total shoulder arthroplastyOverweight/obese categoriesRisk-adjusted multivariate regressionsQuality Improvement Program databaseElevated body mass indexBody mass index groupsLower body mass indexPrimary total shoulder arthroplastyNormal BMI patientsComplications of patientsSerious adverse eventsImprovement Program databaseNormal-weight subjectsBMI patientsFragile cohortDiabetes Status Affects Odds of Body Mass Index-dependent Adverse Outcomes After Total Hip Arthroplasty.
Kebaish KJ, Puvanesarajah V, Rao S, Zhang B, Ottesen TD, Grauer JN, Khanuja H. Diabetes Status Affects Odds of Body Mass Index-dependent Adverse Outcomes After Total Hip Arthroplasty. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: 71-77. PMID: 32404681, DOI: 10.5435/jaaos-d-20-00028.Peer-Reviewed Original ResearchConceptsBody mass indexSerious adverse eventsTotal hip arthroplastyAdverse eventsAdverse outcomesHip arthroplastyNational Surgical Quality Improvement Program databaseInsulin-dependent diabetes mellitus (IDDM) patientsQuality Improvement Program databaseNormal body mass indexPrimary total hip arthroplastyImprovement Program databaseDiabetes mellitus patientsDependent diabetes mellitusMultivariate logistic regressionPatient's medical historyDiabetes groupPerioperative outcomesPerioperative riskObese patientsDiabetes mellitusMellitus patientsNIDDM patientsBMI cutoffsIncreased odds
2020
Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis
Galivanche AR, Gala R, Bagi PS, Boylan AJ, Dussik CM, Coutinho PD, Grauer JN, Varthi AG. Perioperative Outcomes in 17,947 Patients Undergoing 2-Level Anterior Cervical Discectomy and Fusion Versus 1-Level Anterior Cervical Corpectomy for Treatment of Cervical Degenerative Conditions: A Propensity Score Matched National Surgical Quality Improvement Program Analysis. Neurospine 2020, 17: 871-878. PMID: 33401865, PMCID: PMC7788425, DOI: 10.14245/ns.2040134.067.Peer-Reviewed Original ResearchBody mass indexCervical degenerative conditionsAnterior cervical corpectomyAnterior cervical discectomyOperative timeFunctional statusCervical corpectomyAdverse eventsCervical discectomyNational Surgical Quality Improvement Program analysisNational Surgical Quality Improvement Program databaseDegenerative conditionsQuality Improvement Program databasePropensity scoreMultivariate logistic regression analysisAnesthesiologists physical status classificationMinor adverse eventsSerious adverse eventsImprovement Program databasePhysical status classificationShorter operative timeHigher functional statusMultivariate logistic regressionLogistic regression analysisASA PS classificationUnderweight patients are an often under looked “At risk” population after undergoing posterior cervical spine surgery
Ottesen TD, Bagi PS, Malpani R, Galivanche AR, Varthi AG, Grauer JN. Underweight patients are an often under looked “At risk” population after undergoing posterior cervical spine surgery. North American Spine Society Journal (NASSJ) 2020, 5: 100041. PMID: 35141608, PMCID: PMC8820029, DOI: 10.1016/j.xnsj.2020.100041.Peer-Reviewed Original ResearchBody mass indexPosterior cervical spine surgeryCervical spine surgeryAdverse eventsBMI categoriesBMI spectrumSpine surgeryNational Surgical Quality Improvement Program databaseRisk-adjusted multivariate regressionsQuality Improvement Program databaseHigher body mass indexLower body mass indexOutcomes of patientsImprovement Program databaseNormal-weight subjectsCategory of patientsSpine surgery outcomesUnderweight patientsPatient demographicsBMI groupsMass indexAdverse outcomesSurgery outcomesProgram databaseInclusion criteriaUnderweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery
Ottesen TD, Malpani R, Galivanche AR, Zogg CK, Varthi AG, Grauer JN. Underweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery. The Spine Journal 2020, 20: 1085-1095. PMID: 32194246, PMCID: PMC7380546, DOI: 10.1016/j.spinee.2020.03.007.Peer-Reviewed Original ResearchConceptsAnterior cervical spine surgeryBody mass indexCervical spine surgeryNational Surgical Quality Improvement Program databaseSuper morbidly obese patientsQuality Improvement Program databaseWorld Health Organization categoriesMorbidly obese patientsImprovement Program databaseObese patientsAdverse eventsAdverse outcomesSpine surgeryUnderweight patientsPostoperative infectionProgram databaseSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisAnterior cervical spine proceduresOverweight/obese categoriesThirty-day adverse eventsHigher body mass indexLower body mass indexAdverse outcome categoriesNormal BMI patients
2018
What Associations Exist Between Comorbidity Indices and Postoperative Adverse Events After Total Shoulder Arthroplasty?
Fu MC, Ondeck NT, Nwachukwu BU, Garcia GH, Gulotta LV, Verma NN, Grauer JN. What Associations Exist Between Comorbidity Indices and Postoperative Adverse Events After Total Shoulder Arthroplasty? Clinical Orthopaedics And Related Research® 2018, 477: 881-890. PMID: 30614913, PMCID: PMC6437372, DOI: 10.1097/corr.0000000000000624.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramBody mass indexTotal shoulder arthroplastyPostoperative adverse eventsComorbidity indexAdverse eventsHighest AUCShoulder arthroplastyAnthropometric variablesSurgical Quality Improvement ProgramReverse total shoulder arthroplastyDiscriminative abilityCharlson Comorbidity IndexThirty-day outcomesSevere adverse eventsPreoperative risk stratificationModerate discriminative abilityYears of ageQuality Improvement ProgramGood discriminative abilityGreater associationCombination of ageAnesthesiologists classificationASA scoreMedical comorbiditiesWhat Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?
McLynn RP, Ondeck NT, Grauer JN, Lindskog DM. What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases? Clinical Orthopaedics And Related Research® 2018, 476: 2381-2388. PMID: 30260860, PMCID: PMC6259894, DOI: 10.1097/corr.0000000000000489.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood TransfusionDatabases, FactualDiaphysesFemaleFemoral FracturesFemurFracture FixationFractures, SpontaneousHumansLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisNeoplasm MetastasisOdds RatioOperative TimePatient DischargePostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsBody mass indexPathologic fractureAdverse eventsProphylactic treatment groupProphylactic treatmentBlood transfusionDisseminated cancerFemoral shaftComplication profileFracture groupFunctional outcomeProphylactic fixationDistal femurTreatment groupsNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseGreater body mass indexPerioperative complication profileProphylactic surgical stabilizationProphylactic surgical treatmentPostoperative adverse eventsAdverse event profileCurrent Procedural Terminology codesImprovement Program databaseMajor adverse eventsThe Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients
McLynn RP, Ottesen TD, Ondeck NT, Cui JJ, Rubin LE, Grauer JN. The Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients. Clinical Orthopaedics And Related Research® 2018, 476: 997-1006. PMID: 29419631, PMCID: PMC5916609, DOI: 10.1007/s11999.0000000000000186.Peer-Reviewed Original ResearchConceptsRothman Index scoresPostdischarge adverse eventsHip fracture surgeryPostdischarge adverse outcomesAdverse eventsASA classRothman IndexHip fractureFracture surgeryIndex scoreGeriatric patientsAdverse outcomesMedical CenterOverall patient statusHip fracture careRoutine laboratory valuesMeasures of comorbidityRisk of complicationsBody mass indexAge 65 yearsPlan of careVulnerable patient populationCondition of patientsAcademic medical centerElectronic medical records