A Model of Human Cortical Microcircuits for the Study of the Development of Epilepsy
Sánchez-Montañés M, Lago-Fernández L, Castellanos N, Merchán-Pérez Á, Arellano J, DeFelipe J. A Model of Human Cortical Microcircuits for the Study of the Development of Epilepsy. Lecture Notes In Computer Science 2002, 2415: 248-253. DOI: 10.1007/3-540-46084-5_41.Peer-Reviewed Original ResearchDevelopment of epilepsyChandelier cellsDevelopment of seizuresHuman neocortical tissueHuman cortical microcircuitsBrain lesionsInhibitory interneuronsNeocortical tissueCortical circuitryEpileptogenic regionEpileptic patientsStructural abnormalitiesEpilepsyCortical microcircuitsSpecific alterationsCell typesCellsPatientsSeizuresThe neuropathology of temporal lobe epilepsy: primary and secondary changes in the cortical circuits and epileptogenicity.
DeFelipe Oroquieta J, Arellano J, Alonso L, Muñoz A. The neuropathology of temporal lobe epilepsy: primary and secondary changes in the cortical circuits and epileptogenicity. Revista De Neurologia 2002, 34: 401-8. PMID: 12040509, DOI: 10.33588/rn.3405.2001403.Peer-Reviewed Original ResearchConceptsTemporal lobe epilepsyPrimary epileptogenic regionEpileptogenic regionEpileptic activitySynaptic reorganizationLobe epilepsySpecific anatomical connectionsMesial sclerosisNeuronal lossPerilesional areaCommon pathologyInitial lesionCortical circuitsHippocampal formationNeuronal circuitsAnatomical connectionsCortical tissueSecondary changesEpilepsySimilar changesLesionsGliosisEpileptogenicitySclerosisPatients