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Casanova J, MacMicking J, Nathan C. Interferon-. Science 2024, 384: eadl2016. PMID: 38635718, DOI: 10.1126/science.adl2016.Peer-Reviewed Original ResearchConceptsMicrobial pathogensMacrophage-activating factorImmune signalingPrevention of morbidityHost defenseProtective immunityHuman defenseInfectious diseases