2006
Age, Rapid-Cycling, and Pharmacotherapy Effects on Ventral Prefrontal Cortex in Bipolar Disorder: A Cross-Sectional Study
Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS. Age, Rapid-Cycling, and Pharmacotherapy Effects on Ventral Prefrontal Cortex in Bipolar Disorder: A Cross-Sectional Study. Biological Psychiatry 2006, 59: 611-618. PMID: 16414030, DOI: 10.1016/j.biopsych.2005.08.031.Peer-Reviewed Original ResearchConceptsHealthy comparison subjectsWhite matter volumeMagnetic resonance imagingMatter volumeBD patientsHigh-resolution structural magnetic resonance imagingYoung adulthoodStructural magnetic resonance imagingTotal brain volumeCross-sectional studyGray matter volumeAge group interactionVentral prefrontal cortexPharmacotherapy effectsPrefrontal cortex functionIllness featuresBD IProtective effectVolume abnormalitiesHC subjectsComparison subjectsBrain volumeVolume deficitsBipolar disorderRapid initial decline
2005
Applications of Morphometric and Diffusion Tensor Magnetic Resonance Imaging to the Study of Brain Abnormalities in the Alcoholism Spectrum
Daurignac E, Toga A, Jones D, Aronen H, Hommer D, Jernigan T, Krystal J, Mathalon D. Applications of Morphometric and Diffusion Tensor Magnetic Resonance Imaging to the Study of Brain Abnormalities in the Alcoholism Spectrum. Alcohol Clinical And Experimental Research 2005, 29: 159-166. PMID: 15895490, DOI: 10.1097/01.alc.0000150891.72900.62.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingBrain abnormalitiesAlcohol exposureMicrostructural brain abnormalitiesMicrostructural brain alterationsBrain volume deficitsRecent magnetic resonance imagingPrenatal alcohol exposureWhite matter tract integrityWhite matter tractsStructural MRI methodsDiffusion tensor magnetic resonanceChronic alcoholicsBrain alterationsClinical subtypesMorphometric abnormalitiesAlcoholic drinkingVolume deficitsClinical subpopulationsResonance imagingTract integrityNeuropsychiatric diseasesUnique anatomyMicrostructural disruptionStudy of alcoholism