2010
Observational Methods in Comparative Effectiveness Research
Concato J, Lawler EV, Lew RA, Gaziano JM, Aslan M, Huang GD. Observational Methods in Comparative Effectiveness Research. The American Journal Of Medicine 2010, 123: e16-e23. PMID: 21184862, DOI: 10.1016/j.amjmed.2010.10.004.Peer-Reviewed Original ResearchMeSH KeywordsComparative Effectiveness ResearchEvidence-Based MedicineHumansObservationQualitative ResearchRandomized Controlled Trials as TopicResearch DesignTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsConceptsComparative effectiveness researchObservational studyGroup of patientsVeterans Health AdministrationEffectiveness researchSpecific medical conditionsPatient-oriented researchCorresponding study designPatient populationTreatment optionsMedical conditionsHealth AdministrationStudy designMedical ailmentsIndividual studiesAvailable optionsPatientsRCTsOptionsProminent featureStudyAdministrationTrials
2000
Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs
Concato J, Shah N, Horwitz R. Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs. New England Journal Of Medicine 2000, 342: 1887-1892. PMID: 10861325, PMCID: PMC1557642, DOI: 10.1056/nejm200006223422507.Peer-Reviewed Original ResearchMeSH KeywordsAnticholesteremic AgentsBCG VaccineBreast NeoplasmsCase-Control StudiesCohort StudiesFemaleHumansHypertensionMammographyMeta-Analysis as TopicRandomized Controlled Trials as TopicResearch DesignTherapeuticsTreatment OutcomeConceptsCase-control studyObservational studyBacille Calmette-Guérin (BCG) vaccineCalmette-Guérin vaccineRandomized clinical trialsClinical topicsIndividual observational studiesEffect of vaccinationEffect of treatmentMEDLINE data baseActive tuberculosisControlled TrialsPercent confidence intervalsClinical trialsOdds ratioRelative riskSummary estimatesMajor medical journalsSame interventionTrialsResearch designConfidence intervalsHigh gradeTreatment effectsOriginal report