2006
The Effectiveness of Screening for Prostate Cancer: A Nested Case-Control Study
Concato J, Wells CK, Horwitz RI, Penson D, Fincke G, Berlowitz DR, Froehlich G, Blake D, Vickers MA, Gehr GA, Raheb NH, Sullivan G, Peduzzi P. The Effectiveness of Screening for Prostate Cancer: A Nested Case-Control Study. JAMA Internal Medicine 2006, 166: 38-43. PMID: 16401808, DOI: 10.1001/archinte.166.1.38.Peer-Reviewed Original ResearchConceptsDigital rectal examinationCase-control studyCause-specific mortalityCase patientsProstate cancerControl patientsNested Case-Control StudyProstate-specific antigen (PSA) testVeterans Affairs Medical CenterAssociation of screeningBenefits of screeningEffectiveness of screeningVeterans Affairs facilitiesVerbal informed consentEffectiveness of PSADRE screeningCause mortalityPSA testingSurvival benefitRectal examinationAntigen testMedical CenterAmbulatory carePatientsClinical practice
2002
The Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review
Reid M, Boutros N, O'Connor P, Cadariu A, Concato J. The Health–Related Effects of Alcohol Use in Older Persons: A Systematic Review. Substance Use & Addiction Journal 2002, 23: 149-164. PMID: 12444348, DOI: 10.1080/08897070209511485.Peer-Reviewed Original ResearchConceptsCause mortalityCognitive impairmentExposure statusFunctional disabilityAlcohol useOlder adultsFunctional impairmentMiddle-aged adult populationParticipants 60 yearsYears of ageEnglish-language studiesExposure-outcome associationsImportant confounding factorsHealth-related effectsEffects of alcoholMagnitude of riskCohort studySubstantial morbidityPercentage of studiesFormer drinkersProspective studyMean ageAlcohol exposureMethodologic qualityOutcome measures