2021
Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion
Darden D, Duong T, Du C, Munir MB, Han FT, Reeves R, Saw J, Zeitler EP, Al-Khatib SM, Russo AM, Minges KE, Curtis JP, Freeman JV, Hsu JC. Sex Differences in Procedural Outcomes Among Patients Undergoing Left Atrial Appendage Occlusion. JAMA Cardiology 2021, 6: 1275-1284. PMID: 34379072, PMCID: PMC8358791, DOI: 10.1001/jamacardio.2021.3021.Peer-Reviewed Original ResearchConceptsHospital adverse eventsMajor adverse eventsAdverse eventsAtrial appendage occlusionMajor bleedingPericardial effusionAppendage occlusionAtrial fibrillationSex differencesCongestive heart failureCoronary artery diseaseAdjusted logistic regression analysisParoxysmal atrial fibrillationLogistic regression analysisMultivariable adjusted logistic regression analysesPrior strokeUncontrolled hypertensionHospital outcomesHospital stayMultivariable adjustmentProlonged hospitalBaseline characteristicsCohort studySelect patientsArtery disease
2020
Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR
Prutkin JM, Wang Y, Escudero CA, Stephenson EA, Minges KE, Curtis JP, Hsu JC. Prevalence, predictors and complications with defibrillation threshold testing in pediatric patients: Results from the NCDR. International Journal Of Cardiology 2020, 305: 44-49. PMID: 31980272, DOI: 10.1016/j.ijcard.2020.01.027.Peer-Reviewed Original ResearchConceptsInadequate defibrillation safety marginDefibrillation safety marginDFT testingDefibrillation threshold testingHospital complicationsPediatric patientsHospital stayICD recipientsNational Cardiovascular Data Registry ICD RegistryThreshold testingLowest successful energyProlonged hospital stayRisk of complicationsTransvenous ICD implantationHospital dischargeICD implantationMultivariable adjustmentICD RegistryPediatric populationRetrospective analysisLower oddsComplicationsPatientsTesting useLittle data
2018
Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014
Goldsweig AM, Wang Y, Forrest JK, Cleman MW, Minges KE, Mangi AA, Aronow HD, Krumholz HM, Curtis JP. Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999–2014. Catheterization And Cardiovascular Interventions 2018, 92: 1104-1115. PMID: 29513365, DOI: 10.1002/ccd.27576.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionVentricular septal ruptureTimely primary PCIMortality ratePrimary PCIPercutaneous repairSeptal ruptureMyocardial infarctionRetrospective cohort studyUnadjusted mortality ratesUnrepaired patientsVSR repairFatal complicationCohort studyAnnual incidenceMedicare feeService beneficiariesPatientsIncidenceStudy periodMortalityHospitalizationInfarctionRepairPCI
2015
Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study)
Gupta A, Chui P, Zhou S, Spertus JA, Geda M, Lorenze N, Lee I, Onofrio G, Lichtman JH, Alexander KP, Krumholz HM, Curtis JP. Frequency and Effects of Excess Dosing of Anticoagulants in Patients ≤55 Years With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention (from the VIRGO Study). The American Journal Of Cardiology 2015, 116: 1-7. PMID: 25937348, PMCID: PMC4466069, DOI: 10.1016/j.amjcard.2015.03.032.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAngioplasty, Balloon, CoronaryAnticoagulantsAntithrombinsBody Mass IndexCohort StudiesFemaleHemorrhageHeparinHirudinsHumansMaleMiddle AgedMyocardial InfarctionPeptide FragmentsPercutaneous Coronary InterventionPlatelet Glycoprotein GPIIb-IIIa ComplexPrevalenceRecombinant ProteinsRisk AssessmentRisk FactorsSex DistributionTreatment OutcomeUnited StatesConceptsPercutaneous coronary interventionGlycoprotein IIb/IIIa inhibitorsIIb/IIIa inhibitorsExcess dosingAcute myocardial infarctionCoronary interventionMultivariable analysisMyocardial infarctionUnderwent Percutaneous Coronary InterventionLower body weightOlder patientsYounger patientsUnfractionated heparinMedical recordsUnivariate analysisAnticoagulant agentsAnticoagulant drugsBody weightPatientsDosingYounger ageLogistic regressionYoung womenAnticoagulantsGender-based differences
2014
Prevalence of Guideline-Directed Medical Therapy Among Patients Receiving Cardiac Resynchronization Therapy Defibrillator Implantation in the National Cardiovascular Data Registry During the Years 2006 to 2008
Schneider PM, Pellegrini CN, Wang Y, Fein AS, Reynolds MR, Curtis JP, Masoudi FA, Varosy PD. Prevalence of Guideline-Directed Medical Therapy Among Patients Receiving Cardiac Resynchronization Therapy Defibrillator Implantation in the National Cardiovascular Data Registry During the Years 2006 to 2008. The American Journal Of Cardiology 2014, 113: 2052-2056. PMID: 24793671, PMCID: PMC4346333, DOI: 10.1016/j.amjcard.2014.03.049.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAged, 80 and overAngiotensin-Converting Enzyme InhibitorsCardiac Resynchronization TherapyCombined Modality TherapyDeath, Sudden, CardiacDefibrillators, ImplantableFemaleFollow-Up StudiesHeart FailureHumansMaleMiddle AgedPractice Guidelines as TopicPrevalenceRegistriesRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment OutcomeUnited StatesVentricular Dysfunction, LeftConceptsGuideline-directed medical therapyCardiac resynchronization therapyImplantable Cardioverter-Defibrillator RegistryAngiotensin II receptor inhibitorΒ-blockersMedical therapyClass IReceptor inhibitorsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryCardiac resynchronization therapy defibrillator implantationLeft ventricular systolic dysfunctionSevere heart failure symptomsAngiotensin-converting enzyme inhibitorNational Cardiovascular Data RegistryClass I indicationsCRT-D implantationHeart failure symptomsVentricular systolic dysfunctionProportion of patientsSelection of patientsReal-world patientsAngiotensin-converting enzymePrevalence of guidelinesContemporaneous guidelinesQuality improvement targets
2013
Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR])
Dev S, Peterson PN, Wang Y, Curtis JP, Varosy PD, Masoudi FA. Prevalence, Correlates, and Temporal Trends in Antiarrhythmic Drug Use at Discharge After Implantable Cardioverter Defibrillator Placement (from the National Cardiovascular Data Registry [NCDR]). The American Journal Of Cardiology 2013, 113: 314-320. PMID: 24216126, DOI: 10.1016/j.amjcard.2013.09.023.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillatorAntiarrhythmic drug useAntiarrhythmic drugsMedian odds ratioHospital dischargeOdds ratioSecondary prevention implantable cardioverter defibrillatorDrug useClass III antiarrhythmic drugsImplantable cardioverter-defibrillator placementMultivariate logistic regression modelHospital-level variationClass III agentsLocal treatment patternsLogistic regression modelsFacility-level variablesAntiarrhythmic useICD implantationICD recipientsICD RegistryHospital variationICD placementTreatment patternsDevice shocksAntiarrhythmic agentsPatient, Physician, and Procedural Factors Influencing the Use of Defibrillation Testing during Initial Implantable Cardioverter Defibrillator Insertion: Findings from the NCDR®
RUSSO AM, WANG Y, AL‐KHATIB S, CURTIS JP, LAMPERT R. Patient, Physician, and Procedural Factors Influencing the Use of Defibrillation Testing during Initial Implantable Cardioverter Defibrillator Insertion: Findings from the NCDR®. Pacing And Clinical Electrophysiology 2013, 36: 1522-1531. PMID: 23981009, DOI: 10.1111/pace.12248.Peer-Reviewed Original ResearchConceptsHospital adverse eventsDFT testingAdverse eventsImplantable cardioverter-defibrillator insertionLeft ventricular ejection fractionCardiac resynchronization therapy devicesPrimary prevention indicationVentricular ejection fractionResynchronization therapy devicesProspective randomized dataImplantable cardioverter defibrillator (ICD) technologyDefibrillation threshold testingPatterns of practiceMore comorbiditiesPrevention indicationDefibrillator insertionEjection fractionHeart failureAtrial arrhythmiasDefibrillation testingIndependent associationProcedural characteristicsTeaching hospitalDefibrillator technologyImplant procedure
2012
The Prevalence and Outcomes of Transradial Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Analysis From the National Cardiovascular Data Registry (2007 to 2011)
Baklanov DV, Kaltenbach LA, Marso SP, Subherwal SS, Feldman DN, Garratt KN, Curtis JP, Messenger JC, Rao SV. The Prevalence and Outcomes of Transradial Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Analysis From the National Cardiovascular Data Registry (2007 to 2011). Journal Of The American College Of Cardiology 2012, 61: 420-426. PMID: 23265340, PMCID: PMC3883049, DOI: 10.1016/j.jacc.2012.10.032.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBlood Loss, SurgicalComparative Effectiveness ResearchDrug-Eluting StentsElectrocardiographyFemaleFemoral ArteryHospital MortalityHumansIntraoperative CareMaleMiddle AgedMyocardial InfarctionOutcome and Process Assessment, Health CarePrevalenceRadial ArteryRegistriesRisk FactorsTime-to-TreatmentTreatment OutcomeUnited StatesConceptsST-segment elevation myocardial infarctionPercutaneous coronary interventionTransradial percutaneous coronary interventionHospital mortalityBalloon timeTransradial PCICoronary interventionProcedural successFemoral approachRadial accessFemoral-access percutaneous coronary interventionNational Cardiovascular Data RegistryLonger median doorPost-PCI bleedingElevation myocardial infarctionLarge national databaseLow bleeding ratesCathPCI RegistryVascular complicationsLonger doorMedian doorFemoral accessMyocardial infarctionBleeding rateAccess site
2011
Implantable Cardioverter-Defibrillator Registry Risk Score Models for Acute Procedural Complications or Death After Implantable Cardioverter-Defibrillator Implantation
Haines DE, Wang Y, Curtis J. Implantable Cardioverter-Defibrillator Registry Risk Score Models for Acute Procedural Complications or Death After Implantable Cardioverter-Defibrillator Implantation. Circulation 2011, 123: 2069-2076. PMID: 21537001, DOI: 10.1161/circulationaha.110.959676.Peer-Reviewed Original ResearchConceptsImplantable cardioverter defibrillator implantationSimple risk scoreCardioverter-defibrillator implantationAdverse eventsRisk scoreLower riskNew York Heart Association class IIILow-risk subsetPrior valve surgeryAcute procedural complicationsChronic lung diseaseRisk stratification schemaAvailable clinical variablesBlood urea nitrogenIntensity of careRisk score modelLogistic regression modelsHospital complicationsAcute complicationsHospital deathValve surgeryICD implantationPostprocedural complicationsICD RegistryProcedural complications
2005
The significance of elevated troponin T in patients with nondialysis‐dependent renal insufficiency: A validation with coronary angiography
Heitner JF, Curtis JP, Haq SA, Corey GR, Newby LK, Jollis JG. The significance of elevated troponin T in patients with nondialysis‐dependent renal insufficiency: A validation with coronary angiography. Clinical Cardiology 2005, 28: 333-336. PMID: 16075826, PMCID: PMC6653870, DOI: 10.1002/clc.4960280706.Peer-Reviewed Original ResearchConceptsPoor renal functionCoronary artery diseaseLength of stayNondialysis-dependent renal insufficiencyElevated troponin TNormal renal functionRenal functionElevated cTnTCoronary angiographyCAD stenosisContrast nephropathyPositive cTnTRenal insufficiencyPrevalence of CADTroponin TSignificant coronary artery diseaseSignificant coronary artery stenosisImpaired renal functionAcute coronary syndromeFuture cardiac eventsInitiation of hemodialysisGlomerular filtration rateCoronary artery stenosisElevated cTnT.Hospital mortality