2019
Outcomes and costs of remote patient monitoring among patients with implanted cardiac defibrillators: An economic model based on the PREDICT RM database
Hummel JP, Leipold RJ, Amorosi SL, Bao H, Deger KA, Jones PW, Kansal AR, Ott LS, Stern S, Stein K, Curtis JP, Akar JG. Outcomes and costs of remote patient monitoring among patients with implanted cardiac defibrillators: An economic model based on the PREDICT RM database. Journal Of Cardiovascular Electrophysiology 2019, 30: 1066-1077. PMID: 30938894, PMCID: PMC6850124, DOI: 10.1111/jce.13934.Peer-Reviewed Original ResearchAgedAged, 80 and overArrhythmias, CardiacCost-Benefit AnalysisDatabases, FactualDeath, Sudden, CardiacDefibrillators, ImplantableElectric CountershockFemaleHealth Care CostsHumansMaleMedicareModels, EconomicPatient ReadmissionPredictive Value of TestsQuality-Adjusted Life YearsRegistriesRemote Sensing TechnologyTelemetryTime FactorsTreatment OutcomeUnited States
2018
Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction
Kini V, Peterson PN, Spertus JA, Kennedy KF, Arnold SV, Wasfy JH, Curtis JP, Bradley SM, Amin AP, Ho PM, Masoudi FA. Clinical Model to Predict 90-Day Risk of Readmission After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004788. PMID: 30354578, PMCID: PMC6214661, DOI: 10.1161/circoutcomes.118.004788.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionPredictors of readmissionSimple risk scoreDays of hospitalizationGroup of patientsProportional hazards regressionCause readmissionCoronary revascularizationClinical characteristicsCohort studyHospital dischargeDiabetes mellitusHeart failureHazards regressionReadmission riskUnique patientsTransitional careACTION RegistryPrimary diagnosisValue-based reimbursementIndividual patientsReadmissionRisk scoreLower riskPredicting Length of Stay and the Need for Postacute Care After Acute Myocardial Infarction to Improve Healthcare Efficiency
Wasfy JH, Kennedy KF, Masoudi FA, Ferris TG, Arnold SV, Kini V, Peterson P, Curtis JP, Amin AP, Bradley SM, French WJ, Messenger J, Ho PM, Spertus JA. Predicting Length of Stay and the Need for Postacute Care After Acute Myocardial Infarction to Improve Healthcare Efficiency. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004635. PMID: 30354547, PMCID: PMC6207219, DOI: 10.1161/circoutcomes.118.004635.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overClinical Decision-MakingDecision Support TechniquesDelivery of Health Care, IntegratedEfficiency, OrganizationalFemaleHumansLength of StayMaleMiddle AgedMyocardial InfarctionPatient DischargePredictive Value of TestsQuality ImprovementQuality Indicators, Health CareRegistriesRisk FactorsSubacute CareTime FactorsTreatment OutcomeUnited StatesConceptsLength of stayAcute myocardial infarctionAcute MI patientsMyocardial infarctionPostacute carePostacute facilitiesMI patientsST-segment elevation myocardial infarctionPostacute care facilityCare of patientsHierarchical logistic regression modelsLogistic regression modelsCoordinated care planningInitial hospitalizationHospital admissionACTION RegistryTraining cohortCare coordinationNational registryMI subgroupCare planningCare facilitiesPatientsProspective testingHospitalizationComparison of Physician Visual Assessment With Quantitative Coronary Angiography in Assessment of Stenosis Severity in China
Zhang H, Mu L, Hu S, Nallamothu BK, Lansky AJ, Xu B, Bouras G, Cohen DJ, Spertus JA, Masoudi FA, Curtis JP, Gao R, Ge J, Yang Y, Li J, Li X, Zheng X, Li Y, Krumholz HM, Jiang L. Comparison of Physician Visual Assessment With Quantitative Coronary Angiography in Assessment of Stenosis Severity in China. JAMA Internal Medicine 2018, 178: 239-247. PMID: 29340571, PMCID: PMC5838612, DOI: 10.1001/jamainternmed.2017.7821.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overChinaCoronary AngiographyCoronary StenosisCoronary VesselsCross-Sectional StudiesFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPercutaneous Coronary InterventionPractice Patterns, Physicians'Predictive Value of TestsProspective StudiesRisk AssessmentSeverity of Illness IndexTime FactorsConceptsPhysician visual assessmentPercutaneous coronary interventionAcute myocardial infarctionQuantitative coronary angiographyStenosis severityCoronary angiographyMean agePCI studiesMean percent diameter stenosisIndependent core laboratoryPercent diameter stenosisCross-sectional studyNon-AMI patientsStandard clinical practiceFractional flow reserveSubset of participantsQCA assessmentCoronary revascularizationMore stenosisCoronary interventionCoronary lesionsChina PatientCoronary angiogramDiameter stenosisMyocardial infarction
2017
Use of Fractional Flow Reserve in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention Does Prior Stress Testing Matter?
Joseph TA, Lehrich J, Chan PS, Curtis JP, Desai NR, Murthy VL, Curzen N, Nallamothu BK. Use of Fractional Flow Reserve in Elderly Patients Undergoing Elective Percutaneous Coronary Intervention Does Prior Stress Testing Matter? JACC Cardiovascular Interventions 2017, 10: 419-420. PMID: 28231913, DOI: 10.1016/j.jcin.2016.12.021.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingCoronary Artery DiseaseElective Surgical ProceduresFemaleFractional Flow Reserve, MyocardialHeart Function TestsHumansMaleMedicarePatient SelectionPercutaneous Coronary InterventionPredictive Value of TestsRisk FactorsTreatment OutcomeUnited States
2016
Development and validation of a simple risk score to predict 30‐day readmission after percutaneous coronary intervention in a cohort of medicare patients
Minges KE, Herrin J, Fiorilli PN, Curtis JP. Development and validation of a simple risk score to predict 30‐day readmission after percutaneous coronary intervention in a cohort of medicare patients. Catheterization And Cardiovascular Interventions 2016, 89: 955-963. PMID: 27515069, PMCID: PMC5397364, DOI: 10.1002/ccd.26701.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlgorithmsDecision Support TechniquesFemaleHumansLogistic ModelsMaleMedicareMultivariate AnalysisOdds RatioPatient ReadmissionPercutaneous Coronary InterventionPredictive Value of TestsRegistriesReproducibility of ResultsRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsRisk of readmissionPCI patientsRisk scoreMultivariable logistic regression modelRisk score developmentDays of dischargeSimple risk scoreTime of dischargeModel c-statisticLogistic regression modelsStepwise selection modelCathPCI RegistryHospital dischargeReadmission ratesClinical factorsRevascularization proceduresValidation cohortC-statisticReadmissionHigh riskMedicare feeLower riskService claimsPatientsCohort
2015
A validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement
Heidenreich PA, Tsai V, Curtis J, Wang Y, Turakhia MP, Masoudi FA, Varosy PD, Goldstein MK. A validated risk model for 1-year mortality after primary prevention implantable cardioverter defibrillator placement. American Heart Journal 2015, 170: 281-289.e2. PMID: 26299225, DOI: 10.1016/j.ahj.2014.12.013.Peer-Reviewed Original ResearchConceptsOne-year mortalityImplantable cardioverter defibrillatorRisk factorsHeart failurePrimary preventionMortality riskRisk scorePrimary prevention implantable cardioverter-defibrillator placementB-type natriuretic peptide valuesImplantable cardioverter-defibrillator placementCardiovascular Disease RegistryPrimary prevention populationNatriuretic peptide valuesChronic lung diseaseSystolic blood pressureSimilar risk factorsBlood urea nitrogenPg/mLLogistic regression modelsPrevention populationICD therapyICD implantationBlood pressureICD RegistryICD placement
2014
Validated Contemporary Risk Model of Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Interventions: Insights From the National Cardiovascular Data Registry Cath‐PCI Registry
Tsai TT, Patel UD, Chang TI, Kennedy KF, Masoudi FA, Matheny ME, Kosiborod M, Amin AP, Weintraub WS, Curtis JP, Messenger JC, Rumsfeld JS, Spertus JA. Validated Contemporary Risk Model of Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Interventions: Insights From the National Cardiovascular Data Registry Cath‐PCI Registry. Journal Of The American Heart Association 2014, 3: e001380. PMID: 25516439, PMCID: PMC4338731, DOI: 10.1161/jaha.114.001380.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAge FactorsAgedBiomarkersComorbidityCreatinineDecision Support TechniquesFemaleGlomerular Filtration RateHumansKidneyMaleMiddle AgedPercutaneous Coronary InterventionPredictive Value of TestsRegistriesRenal DialysisReproducibility of ResultsRisk AssessmentRisk FactorsSeverity of Illness IndexTreatment OutcomeUnited StatesConceptsAcute kidney injuryPercutaneous coronary interventionCardiogenic shockKidney injuryCoronary interventionHeart failureValidation cohortPreventative strategiesRisk of PCIPrior percutaneous coronary interventionAKI prediction modelBaseline renal impairmentConsecutive PCI patientsContemporary risk modelsPrior cerebrovascular diseasePrior heart failureChronic lung diseaseRisk-stratify patientsLocal quality improvement effortsQuality improvement effortsGood discriminationBaseline CKDSTEMI presentationPCI patientsPCI registryPredictors of an Inadequate Defibrillation Safety Margin at ICD Implantation Insights From the National Cardiovascular Data Registry
Hsu JC, Marcus GM, Al-Khatib SM, Wang Y, Curtis JP, Sood N, Parker MW, Kluger J, Lampert R, Russo AM. Predictors of an Inadequate Defibrillation Safety Margin at ICD Implantation Insights From the National Cardiovascular Data Registry. Journal Of The American College Of Cardiology 2014, 64: 256-264. PMID: 25034061, DOI: 10.1016/j.jacc.2014.01.085.Peer-Reviewed Original ResearchConceptsInadequate defibrillation safety marginDefibrillation safety marginSimple risk scoreAdverse eventsRisk scoreNew York Heart Association functional class IIIImplantable cardioverter defibrillator implantationNational Cardiovascular Data RegistrySecondary prevention indicationFunctional class IIIHospital adverse eventsCardioverter-defibrillator implantationIschemic heart diseaseLogistic regression modelsHospital mortalityPrevention indicationICD recipientsMale sexDefibrillation testingRenal dialysisHeart diseaseBiventricular deviceData registryLower riskGreater odds
2013
Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®
Fazel R, Curtis J, Wang Y, Einstein AJ, Smith‐Bindman R, Tsai TT, Chen J, Shah ND, Krumholz HM, Nallamothu BK. Determinants of fluoroscopy time for invasive coronary angiography and percutaneous coronary intervention: Insights from the NCDR®. Catheterization And Cardiovascular Interventions 2013, 82: 1091-1105. PMID: 23703793, DOI: 10.1002/ccd.24996.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionInvasive coronary angiographyHospital-level factorsFluoroscopy timePrior CABGCoronary interventionPrior coronary artery bypassRadiation exposureCoronary artery bypassNumerous clinical scenariosArtery bypassCathPCI RegistryPatient characteristicsCoronary angiographyPCI proceduresModifiable determinantsPatientsClinical scenariosModifiable sourceProcedure complexityCABGMinutesInterventionExposureWide variationSafety of Pacemaker Implantation in Nonagenarians
Mandawat A, Curtis JP, Mandawat A, Njike VY, Lampert R. Safety of Pacemaker Implantation in Nonagenarians. Circulation 2013, 127: 1453-1465. PMID: 23513066, DOI: 10.1161/circulationaha.113.001434.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overArrhythmias, CardiacComorbidityCross-Sectional StudiesFemaleHealth Care CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMultivariate AnalysisOutcome and Process Assessment, Health CarePacemaker, ArtificialPredictive Value of TestsUnited StatesConceptsLength of stayYears of ageSevere comorbiditiesPacemaker implantationUtilization Project Nationwide Inpatient SampleInitial pacemaker implantationCase-mix variationMantel-Haenszel testStepwise linear regression modelHospital mortalityUnadjusted mortalityComplication rateMultivariable analysisUnadjusted outcomesInpatient SampleHealthcare costsPatientsComorbiditiesHierarchical logistic modelsStayNonagenariansMortalityAgeOutcomesComplications
2012
Variation in Use of Dual-Chamber Implantable Cardioverter-Defibrillators: Results From the National Cardiovascular Data Registry
Matlock DD, Peterson PN, Wang Y, Curtis JP, Reynolds MR, Varosy PD, Masoudi FA. Variation in Use of Dual-Chamber Implantable Cardioverter-Defibrillators: Results From the National Cardiovascular Data Registry. JAMA Internal Medicine 2012, 172: 634-641. PMID: 22529229, PMCID: PMC8317619, DOI: 10.1001/archinternmed.2012.394.Peer-Reviewed Original ResearchMeSH KeywordsAgedCluster AnalysisComorbidityCross-Sectional StudiesDeath, Sudden, CardiacDefibrillators, ImplantableEquipment DesignFemaleHospitalsHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisNew EnglandOdds RatioPacemaker, ArtificialPacific StatesPredictive Value of TestsPrimary PreventionRegistriesConceptsDual-chamber ICDDual-chamber devicesPrimary preventionDual-Chamber Implantable CardioverterMultivariate hierarchical logistic regressionNational Cardiovascular Data RegistrySingle-chamber ICDHospital-level variationStrong independent predictorSudden cardiac deathCross-sectional studyHealth care providersHierarchical logistic regressionPacing indicationCardiac deathHospital clusteringIndependent predictorsPatient factorsPhysician factorsHospital ratesImplantable cardioverterCare providersIdentical patientsCurrent evidenceData registry
2011
Elevated B-Type Natriuretic Peptide Is Associated With Increased In-Hospital Mortality or Cardiac Arrest in Patients Undergoing Implantable Cardioverter-Defibrillator Implantation
Wei S, Loyo-Berríos NI, Haigney MC, Cheng H, Pinnow EE, Mitchell KR, Beachy JH, Woodward AM, Wang Y, Curtis JP, Marinac-Dabic D. Elevated B-Type Natriuretic Peptide Is Associated With Increased In-Hospital Mortality or Cardiac Arrest in Patients Undergoing Implantable Cardioverter-Defibrillator Implantation. Circulation Cardiovascular Quality And Outcomes 2011, 4: 346-354. PMID: 21487093, DOI: 10.1161/circoutcomes.110.943621.Peer-Reviewed Original ResearchConceptsElevated BNP levelsHospital mortalityCardiac arrestBNP levelsICD implantationElevated B-type natriuretic peptide (BNP) levelsNational Cardiovascular Data Registry ICD RegistryB-type natriuretic peptide levelsElevated B-type natriuretic peptideIncreased In-Hospital MortalityB-type natriuretic peptideImplantable cardioverter defibrillator implantationBiventricular ICD implantationHigh BNP groupNatriuretic peptide levelsIn-Hospital MortalityCardioverter-defibrillator implantationHierarchical logistic regressionBNP measurementHospital deathPeriprocedural complicationsRenal dysfunctionComplication rateBNP groupHeart failure
2007
Preventing tomorrow's sudden cardiac death today Part I: Current data on risk stratification for sudden cardiac death
Al-Khatib SM, Sanders GD, Bigger JT, Buxton AE, Califf RM, Carlson M, Curtis A, Curtis J, Fain E, Gersh BJ, Gold MR, Haghighi-Mood A, Hammill SC, Healey J, Hlatky M, Hohnloser S, Kim RJ, Lee K, Mark D, Mianulli M, Mitchell B, Prystowsky EN, Smith J, Steinhaus D, Zareba W, conference F. Preventing tomorrow's sudden cardiac death today Part I: Current data on risk stratification for sudden cardiac death. American Heart Journal 2007, 153: 941-950. PMID: 17540194, DOI: 10.1016/j.ahj.2007.03.003.Peer-Reviewed Original ResearchConceptsSudden cardiac deathRisk stratificationCardiac deathHeart diseasePrevention of SCDLeft ventricular ejection fractionDuke Clinical Research InstituteOvert heart diseaseVentricular ejection fractionStructural heart diseaseHeart Rhythm SocietyClinical Research InstituteImplantable cardioverter defibrillatorCurrent dataEjection fractionSuch patientsSCD eventsCardioverter defibrillatorUS FoodDrug AdministrationPredictive valuePatientsDuke CenterClinical cardiologyEffective prevention
2005
The significance of elevated troponin T in patients with nondialysis‐dependent renal insufficiency: A validation with coronary angiography
Heitner JF, Curtis JP, Haq SA, Corey GR, Newby LK, Jollis JG. The significance of elevated troponin T in patients with nondialysis‐dependent renal insufficiency: A validation with coronary angiography. Clinical Cardiology 2005, 28: 333-336. PMID: 16075826, PMCID: PMC6653870, DOI: 10.1002/clc.4960280706.Peer-Reviewed Original ResearchConceptsPoor renal functionCoronary artery diseaseLength of stayNondialysis-dependent renal insufficiencyElevated troponin TNormal renal functionRenal functionElevated cTnTCoronary angiographyCAD stenosisContrast nephropathyPositive cTnTRenal insufficiencyPrevalence of CADTroponin TSignificant coronary artery diseaseSignificant coronary artery stenosisImpaired renal functionAcute coronary syndromeFuture cardiac eventsInitiation of hemodialysisGlomerular filtration rateCoronary artery stenosisElevated cTnT.Hospital mortality
2004
The Prognostic Value of Vasodilator Myocardial Perfusion Imaging in Octogenarians
Curtis JP, Ko DT, Wang Y, Wackers FJ, Foody JM. The Prognostic Value of Vasodilator Myocardial Perfusion Imaging in Octogenarians. The American Journal Of Geriatric Cardiology 2004, 13: 239-245. PMID: 15365286, DOI: 10.1111/j.1076-7460.2004.03126.x.Peer-Reviewed Original ResearchConceptsMyocardial perfusion imagingPerfusion imagingVasodilator myocardial perfusion imagingAbnormal myocardial perfusion imagingTomography myocardial perfusion imagingMortality of octogenariansSPECT myocardial perfusion imagingLarge perfusion defectsSingle photon emissionStress defectsAggressive managementCrude mortalityMultivariable analysisPrognostic valuePerfusion defectsCardiac diseaseOctogenariansDefect reversibilityMortalitySPECT imagingStrongest predictorPhoton emissionImagingPatientsDisease
2003
The association of left ventricular ejection fraction, mortality, and cause of death in stable outpatients with heart failure
Curtis JP, Sokol SI, Wang Y, Rathore SS, Ko DT, Jadbabaie F, Portnay EL, Marshalko SJ, Radford MJ, Krumholz HM. The association of left ventricular ejection fraction, mortality, and cause of death in stable outpatients with heart failure. Journal Of The American College Of Cardiology 2003, 42: 736-742. PMID: 12932612, DOI: 10.1016/s0735-1097(03)00789-7.Peer-Reviewed Original ResearchMeSH KeywordsAgedCause of DeathFemaleHeart FailureHumansMaleMiddle AgedOutpatientsPredictive Value of TestsPrognosisStroke VolumeSurvival AnalysisConceptsLeft ventricular ejection fractionVentricular ejection fractionHeart failureCause of deathLVEF groupHF patientsMultivariable adjustmentEjection fractionStable outpatientsAssociation of LVEFHigher left ventricular ejection fractionLow left ventricular ejection fractionDigitalis Investigation Group trialHigh LVEF groupStable HF patientsPrognostic importanceAbsolute riskPrognostic indicatorSinus rhythmGroup trialsMortality ratePatientsMortalityDeathOutpatients