2022
Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices
Price M, Friedman D, Du C, Wang Y, Lin Z, Curtis J, Freeman J. Comparative Safety of Transcatheter LAAO With the First-Generation Watchman and Next-Generation Watchman FLX Devices. JACC Cardiovascular Interventions 2022, 15: 2115-2123. PMID: 36357014, DOI: 10.1016/j.jcin.2022.09.002.Peer-Reviewed Original ResearchConceptsHospital major adverse eventsMajor adverse eventsWatchman FLXMajor vascular complicationsMajor bleedingPericardial effusionCardiac arrestDevice embolizationVascular complicationsMyocardial infarctionLower ratesSystemic arterial embolismComposite of deathTransient ischemic attackAtrial appendage occlusionSignificant lower rateBalance of risksHospital mortalityIschemic attackArterial embolismHospital outcomesPrimary endpointStroke preventionAdverse eventsProcedural complications
2021
Predicting In-Hospital Mortality in Patients Undergoing Percutaneous Coronary Intervention
Castro-Dominguez YS, Wang Y, Minges KE, McNamara RL, Spertus JA, Dehmer GJ, Messenger JC, Lavin K, Anderson C, Blankinship K, Mercado N, Clary JM, Osborne AD, Curtis JP, Cavender MA. Predicting In-Hospital Mortality in Patients Undergoing Percutaneous Coronary Intervention. Journal Of The American College Of Cardiology 2021, 78: 216-229. PMID: 33957239, DOI: 10.1016/j.jacc.2021.04.067.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionHospital mortalityQuality improvement effortsCoronary interventionDevelopment cohortValidation cohortRisk-standardized mortality ratesHospital risk-standardized mortality ratesBedside risk scoreHigh-risk patientsIn-Hospital MortalityHospital mortality riskRisk of mortalityLevel of consciousnessProcedural urgencyCathPCI RegistryClinical presentationRisk cohortRisk stratificationCardiovascular instabilityCardiac arrestMortality riskRisk scoreClinical acuityClinical relevance
2020
Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis
Pun PH, Parzynski CS, Friedman DJ, Sanders G, Curtis JP, Al-Khatib SM. Trends in Use and In-Hospital Outcomes of Subcutaneous Implantable Cardioverter Defibrillators in Patients Undergoing Long-Term Dialysis. Clinical Journal Of The American Society Of Nephrology 2020, 15: 1622-1630. PMID: 32967922, PMCID: PMC7646229, DOI: 10.2215/cjn.07920520.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestSubcutaneous ICDTransvenous ICDICD implantsHospital outcomesICD recipientsICD RegistryCardiac arrestHigh riskNational Cardiovascular Data Registry ICD RegistryFirst-time ICD recipientsPropensity score-weighted analysisImplantable cardioverter defibrillator implantationSubcutaneous implantable cardioverter defibrillatorIn-Hospital OutcomesShort-term complicationsCardioverter-defibrillator implantationLong-term dialysisVascular access siteImplantable cardioverter defibrillatorCause deathHospital complicationsHospital stayDefibrillator implantationUS patientsPeriprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure
Fudim M, Ali-Ahmed F, Parzynski CS, Ambrosy AP, Friedman DJ, Pokorney SD, Curtis JP, Fonarow GC, Masoudi FA, Hernandez AF, Al-Khatib SM. Periprocedural Risk and Survival Associated With Implantable Cardioverter-Defibrillator Placement in Older Patients With Advanced Heart Failure. JAMA Cardiology 2020, 5: 643-651. PMID: 32211811, PMCID: PMC7097837, DOI: 10.1001/jamacardio.2020.0391.Peer-Reviewed Original ResearchConceptsAdvanced heart failureAdvanced HF populationHeart transplant listingPeriprocedural complication rateHeart failureSudden cardiac deathComparator groupVentricular assist deviceInotrope useTransplant listingCardiac deathComplication rateHF populationPrimary preventionCardiac arrestNew York Heart Association class IV symptomsNational Cardiovascular Data Registry ICD RegistryAssist deviceLeft ventricular ejection fractionImplantable cardioverter-defibrillator placementAdvanced HF groupClass IV symptomsFirst-time ICDLeft ventricular assist deviceNYHA class II
2018
Periprocedural Risk and Survival after ICD Placement in Patients with Advanced Heart Failure
Fudim M, Parzynski C, Pokorney S, Ambrosy A, Friedman D, Curtis J, Fonarow G, Masoudi F, Hernandez A, Al-Khatib S. Periprocedural Risk and Survival after ICD Placement in Patients with Advanced Heart Failure. Journal Of Cardiac Failure 2018, 24: s63. DOI: 10.1016/j.cardfail.2018.07.275.Peer-Reviewed Original ResearchAdvanced heart failureOrthotopic heart transplantNYHA class IV symptomsClass IV symptomsPrimary prevention ICDsPeriprocedural complication rateHeart failureInitial ICDHF patientsComplication rateICD RegistryPrimary preventionCardiac arrestNational Cardiovascular Data Registry ICD RegistryDiagnosis of HFCause survival ratesICD/CRTNYHA class IVAdvanced HF patientsIschemic heart diseaseAdditional prospective researchSudden cardiac deathCRT-D devicesSudden cardiac arrestCox hazard model
2016
Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States
Friedman DJ, Parzynski CS, Varosy PD, Prutkin JM, Patton KK, Mithani A, Russo AM, Curtis JP, Al-Khatib SM. Trends and In-Hospital Outcomes Associated With Adoption of the Subcutaneous Implantable Cardioverter Defibrillator in the United States. JAMA Cardiology 2016, 1: 900-911. PMID: 27603935, PMCID: PMC5112106, DOI: 10.1001/jamacardio.2016.2782.Peer-Reviewed Original ResearchConceptsSubcutaneous implantable cardioverter defibrillatorPropensity-matched analysisS-ICDHospital outcomesImplantable cardioverter defibrillatorICD implantsComplication rateICD RegistryDFT testingS-ICDsCardioverter defibrillatorNational Cardiovascular Data Registry ICD RegistryHospital complication ratesIn-Hospital OutcomesPrior cardiac arrestLow complication rateS-ICD implantationUse of ICDsSC-ICDICD implantationCardiac arrestMean ageRetrospective analysisMAIN OUTCOMEPatients
2013
Enhanced Mortality Risk Prediction With a Focus on High-Risk Percutaneous Coronary Intervention Results From 1,208,137 Procedures in the NCDR (National Cardiovascular Data Registry)
Brennan JM, Curtis JP, Dai D, Fitzgerald S, Khandelwal AK, Spertus JA, Rao SV, Singh M, Shaw RE, Ho KK, Krone RJ, Weintraub WS, Weaver WD, Peterson ED, Registry C. Enhanced Mortality Risk Prediction With a Focus on High-Risk Percutaneous Coronary Intervention Results From 1,208,137 Procedures in the NCDR (National Cardiovascular Data Registry). JACC Cardiovascular Interventions 2013, 6: 790-799. PMID: 23968699, DOI: 10.1016/j.jcin.2013.03.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCoronary AngiographyCoronary Artery DiseaseDiscriminant AnalysisFemaleHeart ArrestHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPercutaneous Coronary InterventionRegistriesReproducibility of ResultsRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeUnited StatesConceptsPercutaneous coronary interventionRecent cardiac arrestCardiogenic shockInpatient mortalityCardiac arrestPercutaneous Coronary Intervention ResultsBedside risk scoreMain lesion locationHigh-risk patientsChronic total occlusionHigh clinical riskRisk of deathHospital mortality risk modelPre-specified patient subgroupsMortality risk predictionMortality risk modelData collection formRisk prediction modelPCI riskHospital mortalityProcedural mortalityAngiographic predictorsCoronary interventionRisk patientsClinical stability
2011
Elevated B-Type Natriuretic Peptide Is Associated With Increased In-Hospital Mortality or Cardiac Arrest in Patients Undergoing Implantable Cardioverter-Defibrillator Implantation
Wei S, Loyo-Berríos NI, Haigney MC, Cheng H, Pinnow EE, Mitchell KR, Beachy JH, Woodward AM, Wang Y, Curtis JP, Marinac-Dabic D. Elevated B-Type Natriuretic Peptide Is Associated With Increased In-Hospital Mortality or Cardiac Arrest in Patients Undergoing Implantable Cardioverter-Defibrillator Implantation. Circulation Cardiovascular Quality And Outcomes 2011, 4: 346-354. PMID: 21487093, DOI: 10.1161/circoutcomes.110.943621.Peer-Reviewed Original ResearchConceptsElevated BNP levelsHospital mortalityCardiac arrestBNP levelsICD implantationElevated B-type natriuretic peptide (BNP) levelsNational Cardiovascular Data Registry ICD RegistryB-type natriuretic peptide levelsElevated B-type natriuretic peptideIncreased In-Hospital MortalityB-type natriuretic peptideImplantable cardioverter defibrillator implantationBiventricular ICD implantationHigh BNP groupNatriuretic peptide levelsIn-Hospital MortalityCardioverter-defibrillator implantationHierarchical logistic regressionBNP measurementHospital deathPeriprocedural complicationsRenal dysfunctionComplication rateBNP groupHeart failure
2010
Acute Lead Dislodgements and In-Hospital Mortality in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry
Cheng A, Wang Y, Curtis JP, Varosy PD. Acute Lead Dislodgements and In-Hospital Mortality in Patients Enrolled in the National Cardiovascular Data Registry Implantable Cardioverter Defibrillator Registry. Journal Of The American College Of Cardiology 2010, 56: 1651-1656. PMID: 21050975, DOI: 10.1016/j.jacc.2010.06.037.Peer-Reviewed Original ResearchConceptsNational Cardiovascular Data Registry Implantable Cardioverter Defibrillator RegistryImplantable Cardioverter-Defibrillator RegistryLead dislodgementAcute dislodgementHospital deathAdverse eventsNew York Heart Association functional class IV heart failureAtrial fibrillation/flutterCardiac resynchronization therapy-defibrillator deviceClass IV heart failureCommon adverse eventsIn-Hospital MortalityLow ejection fractionChronic lung diseaseMore comorbiditiesCardiac tamponadeMultivariate adjustmentEjection fractionHeart failureNonischemic cardiomyopathyAtrial fibrillationCerebrovascular diseaseCardiac arrestLung diseasePotential confounders