2022
Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88.
Soldatenko A, Hoyt LR, Xu L, Calabro S, Lewis SM, Gallman AE, Hudson KE, Stowell SR, Luckey CJ, Zimring JC, Liu D, Santhanakrishnan M, Hendrickson JE, Eisenbarth SC. Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88. The Journal Of Immunology 2022, 208: 991-997. PMID: 35039331, PMCID: PMC10107373, DOI: 10.4049/jimmunol.2100784.Peer-Reviewed Original ResearchConceptsPattern recognition receptorsDendritic cellsDC activationAdaptive immunityClass of PRRsNon-ABO alloantibodiesRecipient dendritic cellsSplenic dendritic cellsMouse RBCsInflammatory cytokine responseTreatment of anemiaRBC transfusion therapyTransfused RBCsAlloantibody responsesAllogeneic RBCsSerious complicationsCytokine responsesTransfusion therapyRecognition receptorsMyD88TransfusionAlloimmunizationRBCsTRIFUnknown mechanism
2019
Chapter 66 Transfusion-Related Acute Lung Injury
Gokhale A, Hendrickson J. Chapter 66 Transfusion-Related Acute Lung Injury. 2019, 405-408. DOI: 10.1016/b978-0-12-813726-0.00066-0.Peer-Reviewed Original ResearchTransfusion-related acute lung injuryTransfusion-associated circulatory overloadAcute lung injuryHuman leukocyte antigenHuman neutrophil antigensLung injuryBlood productsNon-cardiogenic pulmonary edemaAllogeneic blood transfusionTRALI casesCirculatory overloadBlood transfusionSerious complicationsPulmonary edemaNeutrophil antigensClinical syndromeLeukocyte antigenAcute hypoxiaTransfusionInjuryAntigenHypotensionHypertensionComplicationsEdema