2014
CD8+ T Cells Mediate Antibody-Independent Platelet Clearance Following Transfusion
Patel S, Arthur C, Rodrigues L, Xue C, Zimring J, Hendrickson J, Stowell S. CD8+ T Cells Mediate Antibody-Independent Platelet Clearance Following Transfusion. Blood 2014, 124: 596. DOI: 10.1182/blood.v124.21.596.596.Peer-Reviewed Original ResearchPlatelet-rich plasmaMajor histocompatibility complexNK cell depletionT cellsPlatelet clearanceC57BL/6 recipientsPlatelet transfusionsNK cellsCellular immunityCell depletionAnti-MHC antibodiesSubsequent blood transfusionDepletion of CD8Solid organ allograftsAnti-platelet antibodiesCD8 T cellsClearance of plateletsPlatelet transfusion therapyFlow cytometric analysisLater time pointsC57BL/6 donorsMHC alloantibodiesNK1.1 antibodyOrgan allograftsBlood transfusion
2013
Alterations In Specific Immune Cell Subsets In Children With Sickle Cell Disease
Nickel R, Hendrickson J, Horan J, Garrett A, Robertson J, Osunkwo I, Kean L. Alterations In Specific Immune Cell Subsets In Children With Sickle Cell Disease. Blood 2013, 122: 2208. DOI: 10.1182/blood.v122.21.2208.2208.Peer-Reviewed Original ResearchSickle cell diseaseWhite blood cellsTotal white blood cellsChronic transfusionImmune cell subsetsHU patientsImmune cell populationsSCD patientsT cellsCell subsetsHealthy controlsCell diseaseB cellsGraft rejectionNK cellsImmune systemBone marrow transplant rejectionT-cell subset analysisCell populationsRed blood cell alloimmunizationPediatric sickle cell diseaseSpecific immune cell subsetsDifferent immune cell populationsAbnormal immune activationB cell analysis