2022
Conserved meningeal lymphatic drainage circuits in mice and humans
Jacob L, de Brito Neto J, Lenck S, Corcy C, Benbelkacem F, Geraldo LH, Xu Y, Thomas JM, Kamouh M, Spajer M, Potier MC, Haik S, Kalamarides M, Stankoff B, Lehericy S, Eichmann A, Thomas JL. Conserved meningeal lymphatic drainage circuits in mice and humans. Journal Of Experimental Medicine 2022, 219: e20220035. PMID: 35776089, PMCID: PMC9253621, DOI: 10.1084/jem.20220035.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsGlymphatic SystemHumansLymphatic SystemLymphatic VesselsMagnetic Resonance ImagingMeningesMiceConceptsCerebrospinal fluidVessel wall magnetic resonance imagingDural venous sinusesMagnetic resonance imagingCavernous sinusSystemic injectionImmune surveillanceVenous sinusesGlymphatic systemNeurological diseasesDura materVW-MRIResonance imagingBrain tissueEmissary veinsNeurological pathologiesAnterior partCSF outflowTracer injectionDrainage circuitThree-dimensional anatomyLymphatic vesselsPatientsDiagnostic toolSinus
2019
Lymphatic system in central nervous system
Thomas JL, Jacob L, Boisserand L. Lymphatic system in central nervous system. Médecine/sciences 2019, 35: 55-61. PMID: 30672459, DOI: 10.1051/medsci/2018309.Peer-Reviewed Original ResearchConceptsCentral nervous systemCerebrospinal fluidImmune surveyNervous systemLymphatic vesselsLymphatic systemBrain interstitial fluidHuman CNS diseasesNew therapeutic targetsPeripheral lymphatic systemInterstitial fluid drainageCerebral drainageMeningeal lymphatic vasculatureInterstitial fluidCNS diseaseFluid drainageTherapeutic targetPerivascular spacesTissue drainageConsiderable metabolic activityVasculatureDrainageVesselsMetabolic activityLymphatic vasculature