2019
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells
Charkoftaki G, Thompson DC, Golla JP, Garcia-Milian R, Lam TT, Engel J, Vasiliou V. Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells. Chemico-Biological Interactions 2019, 304: 88-96. PMID: 30851239, PMCID: PMC7988342, DOI: 10.1016/j.cbi.2019.02.030.Peer-Reviewed Original Research
2017
Metabolomic Analysis of Mice Exposed to Gamma Radiation Reveals a Systemic Understanding of Total-Body Exposure
Golla S, Golla JP, Krausz KW, Manna SK, Simillion C, Beyoğlu D, Idle JR, Gonzalez FJ. Metabolomic Analysis of Mice Exposed to Gamma Radiation Reveals a Systemic Understanding of Total-Body Exposure. Radiation Research 2017, 187: 612-629. PMID: 28467754, PMCID: PMC5539505, DOI: 10.1667/rr14592.1.Peer-Reviewed Original ResearchConceptsTotal body exposureRadiation exposureUltra-performance liquid chromatography-electrospray ionization-quadrupole timeBile acid metabolismChronic radiation toxicityMultiple radiation exposuresTissue-specific biomarkersMetabolomic analysisPotential novel approachGamma-irradiated groupsRadiation toxicityResponse markersBone marrowFunctional alterationsLiquid chromatography-electrospray ionization-quadrupole timeTriage protocolSpecific biomarkersDiagnostic markerMetabolic signaturesRadiosensitive tissuesMetabolic changesH postirradiationBiomarkersAcid metabolismTissue-level responses