2023
Development and validation of a model predicting mild stroke severity on admission using electronic health record data
Waddell K, Myers L, Perkins A, Sico J, Sexson A, Burrone L, Taylor S, Koo B, Daggy J, Bravata D. Development and validation of a model predicting mild stroke severity on admission using electronic health record data. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107255. PMID: 37473533, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107255.Peer-Reviewed Original ResearchMeSH KeywordsElectronic Health RecordsHumansIschemic StrokeLogistic ModelsSeverity of Illness IndexStrokeConceptsInitial stroke severityStroke severityElectronic health record dataHealth record dataSevere strokeIschemic strokeStroke careSample patientsMortality risk stratificationRecord dataVeterans Affairs hospitalMild stroke severityMultiple logistic regressionObservational cohortStroke outcomeIndependent predictorsRisk stratificationEHR data elementsPrimary analysisLogistic regressionStrokeValidation sampleSeverityPotent modifierEHR data
2016
Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study
Koo BB, Bravata DM, Tobias LA, Mackey JS, Miech EJ, Matthias MS, Stahl SM, Sico JJ, Fragoso C, Williams LS, Lampert R, Qin L, Yaggi HK. Observational Study of Obstructive Sleep Apnea in Wake-Up Stroke: The SLEEP TIGHT Study. Cerebrovascular Diseases 2016, 41: 233-241. PMID: 26811929, DOI: 10.1159/000440736.Peer-Reviewed Original ResearchMeSH KeywordsAgedBiomarkersBlood PressureBlood Pressure Monitoring, AmbulatoryBrain IschemiaChi-Square DistributionCholesterol, LDLConnecticutCross-Sectional StudiesFemaleHumansIndianaIschemic Attack, TransientLogistic ModelsMaleMiddle AgedOdds RatioOxygenPolysomnographyPrevalenceRandomized Controlled Trials as TopicRisk FactorsSeverity of Illness IndexSex FactorsSleepSleep Apnea, ObstructiveStrokeSympathetic Nervous SystemWakefulnessConceptsObstructive sleep apneaDiastolic blood pressureSevere obstructive sleep apneaLow-density lipoproteinBlood pressureSleep apneaSerum catecholaminesAmbulatory blood pressure monitoringBaseline diastolic blood pressureMean body mass indexB-type natriuretic peptideHigher diastolic blood pressureMore oxygen desaturationTransient ischemic attackIschemic stroke patientsAmbulatory blood pressureHistory of strokeBody mass indexC-reactive proteinBlood pressure monitoringOxygen desaturation eventsGender-stratified analysesCross-sectional analysisIschemic attackOSA frequency
2011
Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke
Sico JJ, Concato J, Wells CK, Lo AC, Nadeau SE, Williams LS, Peixoto AJ, Gorman M, Boice JL, Bravata DM. Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke. Journal Of Stroke And Cerebrovascular Diseases 2011, 22: 271-278. PMID: 22100828, DOI: 10.1016/j.jstrokecerebrovasdis.2011.09.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnemiaBrain IschemiaChi-Square DistributionDisability EvaluationFemaleHospice CareHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPatient DischargePredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeUnited StatesYoung AdultConceptsAcute ischemic strokeSevere ischemic strokeSevere strokeHospital mortalityIschemic strokeConsecutive ischemic stroke patientsHealth Stroke Scale scoreAdmission National InstitutesRole of anemiaStroke Scale scoreChronic kidney diseaseIschemic stroke patientsCongestive heart failureAcute myocardial infarctionAdmission anemiaCombined endpointRetrospective cohortStroke severitySymptom onsetHeart failureHospital admissionStroke patientsPoor outcomeKidney diseaseMyocardial infarction