2024
The Interdisciplinary Stroke Team
Bottomley S, Sico J. The Interdisciplinary Stroke Team. 2024, 417-430. DOI: 10.1007/978-3-031-66289-8_35.Peer-Reviewed Original ResearchPrescription Drug Prices: An AAN Position Statement.
Santoro J, Sico J, Burke J, Sarkar K, Turbes M, Evans D, Jordan J. Prescription Drug Prices: An AAN Position Statement. Neurology 2024, 102: e209132. PMID: 38335469, DOI: 10.1212/wnl.0000000000209132.Peer-Reviewed Original ResearchConceptsHigh cost of medicationNeurological disordersDevelopment of novel therapeuticsNeurological diseasesOrphan Drug ActTherapeutic optionsCost of medicationsHigh-value careCost of prescription drugsPrescription drug pricesRare diseaseTreat rare diseasesPatientsNovel therapeuticsTreat neurological disordersDrug ActCost containment effortsChronic neurological conditionsEffective prescription medicationsMedicationPrescriber accessPrescription medicationsTherapyHealthcare systemApproval pathway
2023
Complex Patient Navigation by Veteran Patients in the Veterans Health Administration (VHA) for Chronic Headache Disease: A Qualitative Study
Lindsey H, Goldman R, Riley S, Baird S, Burrone L, Grinberg A, Fenton B, Sico J, Damush T. Complex Patient Navigation by Veteran Patients in the Veterans Health Administration (VHA) for Chronic Headache Disease: A Qualitative Study. Journal Of Patient Experience 2023, 10: 23743735231151547. PMID: 36710997, PMCID: PMC9880564, DOI: 10.1177/23743735231151547.Peer-Reviewed Original ResearchVeterans Health AdministrationHeadache careHeadache diseaseHealth AdministrationMost patientsHealthcare providersEvidence-based careMultiple healthcare providersPatient navigationVeteran patientsHeadache centerChronic headachePatient satisfactionSpecialty careHeadache specialistsHeadache treatmentMultiple healthcare systemsPatientsCareTimely accessDiseaseThematic qualitative analysisAdministrationHealthcare systemHigh satisfactionUnderstanding headache classification coding within the veterans health administration using ICD-9-CM and ICD-10-CM in fiscal years 2014–2017
Fodeh S, Fenton B, Wang R, Skanderson M, Altalib H, Kuruvilla D, Schindler E, Haskell S, Brandt C, Sico J. Understanding headache classification coding within the veterans health administration using ICD-9-CM and ICD-10-CM in fiscal years 2014–2017. PLOS ONE 2023, 18: e0279163. PMID: 36598881, PMCID: PMC9812322, DOI: 10.1371/journal.pone.0279163.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationHeadache diagnosisICD-10-CMICD-10-CM diagnosisICD-10-CM codingSpecialty care clinicsSpecific headache diagnosesICD-9-CM codingDifferent headache typesICD-9-CMRace/ethnicityHeadache comorbidityHeadache NOSPatient ageCare clinicsChronic conditionsHeadache typesProvider typeSociodemographic factorsHealth AdministrationDiagnosisTwo yearsHeadachePatientsMigraine
2022
Pairing regression and configurational analysis in health services research: modelling outcomes in an observational cohort using a split-sample design
Miech EJ, Perkins AJ, Zhang Y, Myers LJ, Sico JJ, Daggy J, Bravata DM. Pairing regression and configurational analysis in health services research: modelling outcomes in an observational cohort using a split-sample design. BMJ Open 2022, 12: e061469. PMID: 35672067, PMCID: PMC9174826, DOI: 10.1136/bmjopen-2022-061469.Peer-Reviewed Original ResearchConceptsTransient ischemic attackLogistic regression modelsHealth services researchSet of patientsOverall sample prevalenceObservational cohortLogistic regressionSample prevalenceRecurrent ischemic strokeVeterans Affairs hospitalRegression modelsServices researchIschemic attackRecurrent strokeCause mortalityCombined endpointIschemic strokePatient outcomesDeath outcomesCare outcomesPatientsSecondary analysisPrevalenceOutcomesCohortTelehealth perceptions and utilization for the delivery of headache care before and during the COVID‐19 pandemic: A mixed‐methods study
Grinberg AS, Fenton BT, Wang K, Lindsey H, Goldman RE, Baird S, Riley S, Burrone L, Seng EK, Damush TM, Sico JJ. Telehealth perceptions and utilization for the delivery of headache care before and during the COVID‐19 pandemic: A mixed‐methods study. Headache The Journal Of Head And Face Pain 2022, 62: 613-623. PMID: 35545754, PMCID: PMC9348149, DOI: 10.1111/head.14310.Peer-Reviewed Original ResearchConceptsVeterans Health Administration facilitiesTelehealth deliveryHeadache centerHeadache careAdministration facilitiesCoronavirus disease 2019 (COVID-19) pandemicUtilization of telehealthDisease 2019 pandemicRace/ethnicityPatient ageTelephone visitsPerson appointmentsTelehealth visitsOutpatient visitsPatient groupPatient preferencesHeadache disordersPerson visitsHeadache treatmentMultiple delivery methodsPatientsPatient engagementProviders' perceptionsHeadache servicesPatient accessEssential components of care in a multidisciplinary headache center: Perspectives from headache neurology specialists
Goldman RE, Damush TM, Kuruvilla DE, Lindsey H, Baird S, Riley S, BS L, Grinberg AS, Seng EK, Fenton BT, Sico JJ. Essential components of care in a multidisciplinary headache center: Perspectives from headache neurology specialists. Headache The Journal Of Head And Face Pain 2022, 62: 306-318. PMID: 35293614, DOI: 10.1111/head.14277.Peer-Reviewed Original ResearchConceptsMultidisciplinary headache centerHeadache centerHeadache careNeurology specialistsChronic headacheIntegrative health modalitiesBotulinum toxin injectionImmersion/crystallization techniqueType of careSemi-structured telephone interviewsBehavioral health practitionersCognitive behavioral therapyToxin injectionMultidisciplinary careNerve blockPain managementUnsuccessful treatmentHeadache specialistsNew medicationsPhysical therapySuccessful careMultiple doctorsPatientsOccupational therapySleep medicineComplementary and integrative medicine perspectives among veteran patients and VHA healthcare providers for the treatment of headache disorders: a qualitative study
Kuruvilla DE, Lindsey H, Grinberg AS, Goldman RE, Riley S, Baird S, Fenton BT, Sico JJ, Damush TM. Complementary and integrative medicine perspectives among veteran patients and VHA healthcare providers for the treatment of headache disorders: a qualitative study. BMC Complementary Medicine And Therapies 2022, 22: 22. PMID: 35078450, PMCID: PMC8790919, DOI: 10.1186/s12906-022-03511-6.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationVeteran patientsHeadache managementClinical providersBackgroundThe Veterans Health AdministrationFavorable adverse effect profileVHA healthcare providersAdverse effect profileManagement of veteransChronic headache managementCIM modalitiesWhole health systemEffect profileHeadache centerChronic headacheHeadache disordersPatients' perceptionsHeadache treatmentSafe additionPatientsTreatment efficacyIntegrative medicineHealth AdministrationProviders' perceptionsHealthcare providersThe Primary Care Management of Headache: Synopsis of the 2020 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline
Sico JJ, Macedo F, Lewis J, Spevak C, Vogsland R, Ford A, Skop K, Sall J. The Primary Care Management of Headache: Synopsis of the 2020 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline. Military Medicine 2022, 187: e1091-e1102. PMID: 35022782, DOI: 10.1093/milmed/usab490.Peer-Reviewed Original ResearchConceptsClinical practice guidelinesPractice guidelinesDefense Clinical Practice GuidelineJoint clinical practice guidelineTrustworthy clinical practice guidelinesPractice Work GroupMedication overuse headachePrimary care managementPreferences of patientsGuideline development panelMedicine's tenetsPharmacologic managementRecommendations AssessmentOveruse headacheGuideline panelCare managementHeadacheDevelopment panelVeterans AffairsClinical stakeholdersPatientsGuidelinesIndividual needsDepartmentPrevention
2021
Hospital Factors, Performance on Process Measures After Transient Ischemic Attack, and 90-Day Ischemic Stroke Incidence
Levine DA, Perkins AJ, Sico JJ, Myers LJ, Phipps MS, Zhang Y, Bravata DM. Hospital Factors, Performance on Process Measures After Transient Ischemic Attack, and 90-Day Ischemic Stroke Incidence. Stroke 2021, 52: 2371-2378. PMID: 34039034, PMCID: PMC8238890, DOI: 10.1161/strokeaha.120.031721.Peer-Reviewed Original ResearchConceptsIschemic stroke incidenceStroke incidenceHospital factorsPhysician staffingTIA patientsHypertension controlProcess measuresModerate potency statinTransient ischemic attackDays of dischargeEmergency department dischargeVeterans Affairs hospitalEligible patientsIschemic attackStatin useAntithrombotic useEmergency departmentEmergency physiciansInpatient unitDay 2HospitalPatient volumeFiscal year 2015PatientsIncidenceDeintensification or No Statin Treatment Is Associated With Higher Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack
Dearborn-Tomazos JL, Hu X, Bravata DM, Phadke MA, Baye FM, Myers LJ, Concato J, Zillich AJ, Reeves MJ, Sico JJ. Deintensification or No Statin Treatment Is Associated With Higher Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack. Stroke 2021, 52: 2521-2529. PMID: 34015937, DOI: 10.1161/strokeaha.120.030089.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic strokeIschemic attackHospital dischargeHospital admissionHigh mortalityVeterans Health Administration facilitiesHigh-potency statinsUnderutilization of statinsHigh potencyStatin doseStatin medicationBaseline characteristicsMost patientsPrescribed statinsStatin treatmentPharmacy filesStatin potencyAtherosclerotic originUS veteransPractice guidelinesStudy populationHigher oddsPatientsStatins“You will eat shoe polish if you think it would help”—Familiar and lesser‐known themes identified from mixed‐methods analysis of a cluster headache survey
Schindler EAD, Cooper V, Quine DB, Fenton BT, Wright DA, Weil MJ, Sico JJ. “You will eat shoe polish if you think it would help”—Familiar and lesser‐known themes identified from mixed‐methods analysis of a cluster headache survey. Headache The Journal Of Head And Face Pain 2021, 61: 318-328. PMID: 33502769, DOI: 10.1111/head.14063.Peer-Reviewed Original ResearchConceptsCluster headache patientsCluster headacheHeadache patientsExercise/physical activityVitamins/supplementsSevere painInterventional investigationDisease management approachTreatment optionsSubgroup analysisPhysical activitySide effectsPatients' thoughtsMixed-methods analysisSecondary analysisFree-text responsesHeadachePatientsIllicit substancesDisease managementAdult participantsHeadache medicine
2020
Atypical case of Miller-Fisher syndrome presenting with severe dysphagia and weight loss
Patel K, Nussbaum E, Sico J, Merchant N. Atypical case of Miller-Fisher syndrome presenting with severe dysphagia and weight loss. BMJ Case Reports 2020, 13: e234316. PMID: 32467120, PMCID: PMC7259814, DOI: 10.1136/bcr-2020-234316.Peer-Reviewed Case Reports and Technical NotesConceptsMiller Fisher syndromeAtypical casesLower extremity muscle weaknessWeight lossExtremity muscle weaknessFormal swallow evaluationThorough neurological examinationResolution of symptomsAlbuminocytological dissociationIntravenous immunoglobulinPresenting symptomProgressive dysphagiaSevere dysphagiaSwallow evaluationSymptom onsetExtraocular movementsNeurological examinationMuscle weaknessPhysical examinationAntibody titresDysphagiaCerebrospinal fluidGait stabilityPatientsSyndromePrevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward
Diaz MM, Hu X, Fenton BT, Kimuli I, Lee A, Lindsey H, Bigelow JK, Maiser S, Altalib HH, Sico JJ. Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward. BMC Neurology 2020, 20: 42. PMID: 32005185, PMCID: PMC6995141, DOI: 10.1186/s12883-020-1627-5.Peer-Reviewed Original ResearchConceptsNeurology wardHead traumaHospital mortalityWorse survivalCommon diagnosisMultivariate Cox proportional hazard modelingSub-Saharan African hospitalsCox proportional hazard modelingKaplan-Meier survival curvesConclusionsIn-hospital mortalityPatient-level predictorsHigh-risk groupProportional hazard modelingDiagnosis of infectionTime of deathIndex hospitalizationHospital admissionMulago HospitalNeurologic illnessAfrican hospitalsNeurologic diseaseSurvival curvesPatientsHazard modelingMortality
2019
American Academy of Neurology members' preparedness to treat sexual and gender minorities.
Rosendale N, Ostendorf T, Evans DA, Weathers A, Sico JJ, Randall J, Hinson HE. American Academy of Neurology members' preparedness to treat sexual and gender minorities. Neurology 2019, 93: 159-166. PMID: 31201295, DOI: 10.1212/wnl.0000000000007829.Peer-Reviewed Original ResearchConceptsNeurologic careSGM patientsAmerican AcademyHealth care servicesGender minority patientsNeurologic healthNeurologic illnessMost neurologistsMinority patientsSelf-reported knowledgeResponse rateFuture educational offeringsCare servicesPatientsSocial determinantsClinical preparednessMinority of respondentsNeurologistsSGM individualsGender identitySGM identitiesSexual orientationAAN membersMost respondentsCareOut with the Old and In with the New - Understanding Barriers and Facilitators in Obtaining “New” Blood Pressure Goal for Patients with Ischemic Stroke (P5.3-001)
Sico J, Burrone L, Bottomley S, Keefner L, Damush T, Hurd P, Fenton B. Out with the Old and In with the New - Understanding Barriers and Facilitators in Obtaining “New” Blood Pressure Goal for Patients with Ischemic Stroke (P5.3-001). Neurology 2019, 92 DOI: 10.1212/wnl.92.15_supplement.p5.3-001.Peer-Reviewed Original Research
2018
Uncertainty as a Key Influence in the Decision To Admit Patients with Transient Ischemic Attack
Homoya BJ, Damush TM, Sico JJ, Miech EJ, Arling GW, Myers LJ, Ferguson JB, Phipps MS, Cheng EM, Bravata DM. Uncertainty as a Key Influence in the Decision To Admit Patients with Transient Ischemic Attack. Journal Of General Internal Medicine 2018, 34: 1715-1723. PMID: 30484102, PMCID: PMC6712185, DOI: 10.1007/s11606-018-4735-9.Peer-Reviewed Original ResearchConceptsTransient ischemic attackVA Medical CenterTIA patientsChart review dataAdmission ratesTIA admissionsTIA careABCD2 scoreIschemic attackChart reviewAdministrative dataSubsequent vascular eventsSecondary prevention strategiesSubset of patientsQuality improvement interventionsHigher admission ratesQuality of careKey ResultsProvidersTimely workupVascular eventsEmergency departmentInpatient settingMedical CenterHigh riskPatientsAssociation between admission haematocrit and mortality among men with acute ischaemic stroke
Sico JJ, Myers LJ, Fenton BJ, Concato J, Williams LS, Bravata DM. Association between admission haematocrit and mortality among men with acute ischaemic stroke. Stroke And Vascular Neurology 2018, 3: 160. PMID: 30294472, PMCID: PMC6169611, DOI: 10.1136/svn-2018-000149.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIschemic strokeAdmission haematocritAdjusted ORsChronic Health Evaluation IIIVeterans Health Administration facilitiesFirst year post strokeHours of admissionRisk of deathHaematocrit valuesMultivariate logistic regressionYear post strokeAcute PhysiologyHospital mortalityMedical comorbiditiesPoststroke mortalityStroke severityBlood transfusionSevere anemiaPost strokeHeart diseaseMedical recordsPatient outcomesCardiovascular conditionsPatientsPost‐stroke hypertension control and receipt of health care services among veterans
Kohok DD, Sico JJ, Baye F, Myers L, Coffing J, Kamalesh M, Bravata DM. Post‐stroke hypertension control and receipt of health care services among veterans. Journal Of Clinical Hypertension 2018, 20: 382-387. PMID: 29397583, PMCID: PMC8031130, DOI: 10.1111/jch.13194.Peer-Reviewed Original ResearchConceptsPrimary careHypertension managementRecurrent stroke rateGoal blood pressureRetrospective cohort studyAcute ischemic strokeIschemic stroke patientsIschemic stroke admissionsFuture intervention studiesHealth care servicesBP controlBP trajectoriesPC visitsGoal BPHypertension controlStroke admissionsCohort studyIschemic strokeBlood pressureMean BPHealthcare utilizationMedian timeStroke patientsStroke ratePatients
2012
Thrombocytopenia and In-hospital Mortality Risk among Ischemic Stroke Patients
Sico JJ, Phipps MS, Concato J, Wells CK, Lo AC, Nadeau SE, Williams LS, Peixoto AJ, Gorman M, Boice JL, Bravata DM. Thrombocytopenia and In-hospital Mortality Risk among Ischemic Stroke Patients. Journal Of Stroke And Cerebrovascular Diseases 2012, 22: e99-e102. PMID: 22974703, DOI: 10.1016/j.jstrokecerebrovasdis.2012.08.005.Peer-Reviewed Original ResearchConceptsAcute ischemic strokeIschemic stroke patientsHospital mortalityIschemic strokeStroke patientsHealth Stroke Scale scoreAcute ischemic stroke patientsStroke Scale scorePredictors of mortalityLogistic regression modelingAdmission thrombocytopeniaRetrospective cohortAntiplatelet effectUnadjusted analysesRisk factorsOdds ratioMortality riskThrombocytopeniaPatientsScale scoreHigh mortalityMortalityU.S. hospitalsStrokeNational Institute