2021
Deintensification or No Statin Treatment Is Associated With Higher Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack
Dearborn-Tomazos JL, Hu X, Bravata DM, Phadke MA, Baye FM, Myers LJ, Concato J, Zillich AJ, Reeves MJ, Sico JJ. Deintensification or No Statin Treatment Is Associated With Higher Mortality in Patients With Ischemic Stroke or Transient Ischemic Attack. Stroke 2021, 52: 2521-2529. PMID: 34015937, DOI: 10.1161/strokeaha.120.030089.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic strokeIschemic attackHospital dischargeHospital admissionHigh mortalityVeterans Health Administration facilitiesHigh-potency statinsUnderutilization of statinsHigh potencyStatin doseStatin medicationBaseline characteristicsMost patientsPrescribed statinsStatin treatmentPharmacy filesStatin potencyAtherosclerotic originUS veteransPractice guidelinesStudy populationHigher oddsPatientsStatins
2020
Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward
Diaz MM, Hu X, Fenton BT, Kimuli I, Lee A, Lindsey H, Bigelow JK, Maiser S, Altalib HH, Sico JJ. Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward. BMC Neurology 2020, 20: 42. PMID: 32005185, PMCID: PMC6995141, DOI: 10.1186/s12883-020-1627-5.Peer-Reviewed Original ResearchConceptsNeurology wardHead traumaHospital mortalityWorse survivalCommon diagnosisMultivariate Cox proportional hazard modelingSub-Saharan African hospitalsCox proportional hazard modelingKaplan-Meier survival curvesConclusionsIn-hospital mortalityPatient-level predictorsHigh-risk groupProportional hazard modelingDiagnosis of infectionTime of deathIndex hospitalizationHospital admissionMulago HospitalNeurologic illnessAfrican hospitalsNeurologic diseaseSurvival curvesPatientsHazard modelingMortality
2011
Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke
Sico JJ, Concato J, Wells CK, Lo AC, Nadeau SE, Williams LS, Peixoto AJ, Gorman M, Boice JL, Bravata DM. Anemia is Associated with Poor Outcomes in Patients with Less Severe Ischemic Stroke. Journal Of Stroke And Cerebrovascular Diseases 2011, 22: 271-278. PMID: 22100828, DOI: 10.1016/j.jstrokecerebrovasdis.2011.09.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnemiaBrain IschemiaChi-Square DistributionDisability EvaluationFemaleHospice CareHospital MortalityHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient AdmissionPatient DischargePredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexStrokeUnited StatesYoung AdultConceptsAcute ischemic strokeSevere ischemic strokeSevere strokeHospital mortalityIschemic strokeConsecutive ischemic stroke patientsHealth Stroke Scale scoreAdmission National InstitutesRole of anemiaStroke Scale scoreChronic kidney diseaseIschemic stroke patientsCongestive heart failureAcute myocardial infarctionAdmission anemiaCombined endpointRetrospective cohortStroke severitySymptom onsetHeart failureHospital admissionStroke patientsPoor outcomeKidney diseaseMyocardial infarction