2022
Hospitalizations of Children Aged 5–11 Years with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 2020–February 2022
Shi D, Whitaker M, Marks K, Anglin O, Milucky J, Patel K, Pham H, Chai S, Kawasaki B, Meek J, Anderson E, Weigel A, Henderson J, Lynfield R, Ropp S, Muse A, Bushey S, Billing L, Sutton M, Talbot H, Price A, Taylor C, Havers F, Team C. Hospitalizations of Children Aged 5–11 Years with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 2020–February 2022. MMWR Morbidity And Mortality Weekly Report 2022, 71: 574-581. PMID: 35446827, PMCID: PMC9042359, DOI: 10.15585/mmwr.mm7116e1.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationCOVID-19-Associated Hospitalization Surveillance NetworkIntensive care unitAge groupsUnvaccinated childrenPfizer-BioNTech COVID-19 vaccineCumulative hospitalization rateNon-Hispanic black childrenSevere COVID-19Immunization Practices recommendationsUnderlying medical conditionsCDC's Advisory CommitteeImportance of vaccinationEmergency use authorizationUnderlying health conditionsCOVID-19 vaccineCOVID-19SARS-CoV-2Advisory CommitteeCare unitHospitalization ratesVaccination coverageSevere outcomesChildren Aged 5Medical conditions
2021
Risk Factors for Severe COVID-19 in Children
Woodruff R, Campbell A, Taylor C, Chai S, Kawasaki B, Meek J, Anderson E, Weigel A, Monroe M, Reeg L, Bye E, Sosin D, Muse A, Bennett N, Billing L, Sutton M, Talbot H, McCaffrey K, Pham H, Patel K, Whitaker M, McMorrow M, Havers F. Risk Factors for Severe COVID-19 in Children. Pediatrics 2021, 149: e2021053418. PMID: 34935038, PMCID: PMC9213563, DOI: 10.1542/peds.2021-053418.Peer-Reviewed Original ResearchConceptsSevere COVID-19Adjusted risk ratioPopulation-based ratesHospitalized childrenRisk factorsCOVID-19Laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infectionAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionSevere coronavirus disease 2019COVID-19-Associated Hospitalization Surveillance NetworkNon-Hispanic black childrenCoronavirus 2 infectionChronic lung diseaseConfidence intervalsCoronavirus disease 2019COVID-19 vaccineTube dependenceAirway abnormalitiesDiabetes mellitusIllness severityLung diseaseRisk ratioMedical recordsHospital-acquired influenza in the United States, FluSurv-NET, 2011–2012 through 2018–2019
Cummings C, O’Halloran A, Azenkot T, Reingold A, Alden N, Meek J, Anderson E, Ryan P, Kim S, McMahon M, McMullen C, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Talbot H, George A, Reed C, Garg S. Hospital-acquired influenza in the United States, FluSurv-NET, 2011–2012 through 2018–2019. Infection Control And Hospital Epidemiology 2021, 43: 1447-1453. PMID: 34607624, DOI: 10.1017/ice.2021.392.Peer-Reviewed Original ResearchConceptsHospital-acquired influenzaInfluenza-associated hospitalizationsHA influenzaHospital infection control measuresInfluenza Hospitalization Surveillance NetworkFacility-based testingPositive test dateRespiratory symptom onsetAnnual influenza vaccinationHA casesInfection control measuresSymptom onset dateCross-sectional studyYears of agePopulation-based ratesInfluenza vaccinationClinical characteristicsICU careSymptom onsetInfluenza vaccineMechanical ventilationSevere outcomesPatient outcomesInfluenza casesHospitalization
2017
Risk factors for tick exposure in suburban settings in the Northeastern United States
Mead P, Hook S, Niesobecki S, Ray J, Meek J, Delorey M, Prue C, Hinckley A. Risk factors for tick exposure in suburban settings in the Northeastern United States. Ticks And Tick-borne Diseases 2017, 9: 319-324. PMID: 29174449, DOI: 10.1016/j.ttbdis.2017.11.006.Peer-Reviewed Original Research
2016
Increased Antiviral Treatment Among Hospitalized Children and Adults With Laboratory-Confirmed Influenza, 2010–2015
Appiah GD, Chaves SS, Kirley PD, Miller L, Meek J, Anderson E, Oni O, Ryan P, Eckel S, Lynfield R, Bargsten M, Zansky SM, Bennett N, Lung K, McDonald-Hamm C, Thomas A, Brady D, Lindegren ML, Schaffner W, Hill M, Garg S, Fry AM, Campbell AP. Increased Antiviral Treatment Among Hospitalized Children and Adults With Laboratory-Confirmed Influenza, 2010–2015. Clinical Infectious Diseases 2016, 64: 364-367. PMID: 28013261, PMCID: PMC5480237, DOI: 10.1093/cid/ciw745.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAntiviral AgentsChildChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornInfluenza A Virus, H1N1 SubtypeInfluenza, HumanLength of StayLongitudinal StudiesMaleMiddle AgedOseltamivirPandemicsProspective StudiesRetrospective StudiesSeasonsUnited StatesYoung AdultEffectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans
Hinckley A, Meek J, Ray J, Niesobecki S, Connally N, Feldman K, Jones E, Backenson P, White J, Lukacik G, Kay A, Miranda W, Mead P. Effectiveness of Residential Acaricides to Prevent Lyme and Other Tick-borne Diseases in Humans. The Journal Of Infectious Diseases 2016, 214: 182-188. PMID: 26740276, PMCID: PMC10874626, DOI: 10.1093/infdis/jiv775.Peer-Reviewed Original ResearchConceptsTick-borne diseasesHuman-tick encountersMajor public health concernPlacebo-controlled trialMedical record reviewHuman tick-borne diseasesReports of illnessPublic health concernPublic health authoritiesTick-borne diseaseRecord reviewTick biteTick exposureTreatment groupsHealth authoritiesDiseaseHealth concernQuesting ticksHuman outcomesTicksUse of acaricidesIllnessIncidenceTrialsWeeks
2015
Burden of Clostridium difficile Infection in the United States
Lessa F, Mu Y, Bamberg W, Beldavs Z, Dumyati G, Dunn J, Farley M, Holzbauer S, Meek J, Phipps E, Wilson L, Winston L, Cohen J, Limbago B, Fridkin S, Gerding D, McDonald L. Burden of Clostridium difficile Infection in the United States. New England Journal Of Medicine 2015, 372: 825-834. PMID: 25714160, PMCID: PMC10966662, DOI: 10.1056/nejmoa1408913.Peer-Reviewed Original ResearchConceptsClostridium difficile infectionDifficile infectionFirst recurrenceHealth care-associated infectionsCommunity-associated infectionsC. difficile infectionCare-associated infectionsPersons 65 yearsLaboratory-based surveillanceType 1 strainsNumber of deathsNational incidenceMolecular typingC. difficileInfectionIncidenceDeathUnited StatesRecurrenceGeographic areasSample of casesEstimated numberRegression modelsActive populationHealth
2013
Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010
Dawood F, Chaves S, Pérez A, Reingold A, Meek J, Farley M, Ryan P, Lynfield R, Morin C, Baumbach J, Bennett N, Zansky S, Thomas A, Lindegren M, Schaffner W, Finelli L, Network F. Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010. The Journal Of Infectious Diseases 2013, 209: 686-694. PMID: 23986545, DOI: 10.1093/infdis/jit473.Peer-Reviewed Original ResearchConceptsIntensive carePandemic influenzaLaboratory-confirmed influenza hospitalizationsBacteremia/sepsisInfluenza-associated complicationsIntensive care requirementAcute renal failurePopulation-based surveillanceSeverity of complicationsMedian hospitalization durationNinth Revision codesInfluenza hospitalizationsAsthma exacerbationsHospitalization durationInfluenza vaccinationRespiratory failureCommon complicationRenal failureBacterial coinfectionProlonged hospitalizationMedian lengthPrimary preventionRevision codesSeasonal influenzaHospitalized childrenEffectiveness of Nonadjuvanted Monovalent Influenza A(H1N1)pdm09 Vaccines for Preventing Reverse Transcription Polymerase Chain Reaction–Confirmed Pandemic Influenza Hospitalizations: Case-Control Study of Children and Adults at 10 US Influenza Surveillance Network Sites
Thompson M, Sokolow L, Almendares O, Openo K, Farley M, Meek J, Ray J, Kirley P, Reingold A, Aragon D, Hancock E, Baumbach J, Schaffner W, Thomas A, Lynfield R, Ryan P, Monroe M, Cheng P, Fry A, Shay D. Effectiveness of Nonadjuvanted Monovalent Influenza A(H1N1)pdm09 Vaccines for Preventing Reverse Transcription Polymerase Chain Reaction–Confirmed Pandemic Influenza Hospitalizations: Case-Control Study of Children and Adults at 10 US Influenza Surveillance Network Sites. Clinical Infectious Diseases 2013, 57: 1587-1592. PMID: 23956169, PMCID: PMC7314184, DOI: 10.1093/cid/cit551.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed pandemic influenzaCommunity-matched controlsCase-control studyReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionInfluenza hospitalizationsMonovalent influenzaPandemic influenzaSingle dosePolymerase chain reactionVirus infectionInfluenzaChain reactionHospitalizationVaccinePatientsInfectionDose
2012
Guillain-Barré Syndrome During the 2009–2010 H1N1 Influenza Vaccination Campaign: Population-based Surveillance Among 45 Million Americans
Wise M, Viray M, Sejvar J, Lewis P, Baughman A, Connor W, Danila R, Giambrone G, Hale C, Hogan B, Meek J, Murphree R, Oh J, Reingold A, Tellman N, Conner S, Singleton J, Lu P, DeStefano F, Fridkin S, Vellozzi C, Morgan O. Guillain-Barré Syndrome During the 2009–2010 H1N1 Influenza Vaccination Campaign: Population-based Surveillance Among 45 Million Americans. American Journal Of Epidemiology 2012, 175: 1110-1119. PMID: 22582209, PMCID: PMC3888111, DOI: 10.1093/aje/kws196.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolFemaleGuillain-Barre SyndromeHealth PromotionHumansIncidenceInfantInfluenza A Virus, H1N1 SubtypeInfluenza VaccinesInfluenza, HumanMaleMiddle AgedPopulation SurveillanceProduct Surveillance, PostmarketingRisk AssessmentTime FactorsUnited StatesYoung AdultConceptsGuillain-Barré syndromePopulation-based surveillanceGBS casesPH1N1 vaccineInfluenza A (H1N1) 2009 monovalent vaccineRate of GBSEmerging Infections Program sitesSex-adjusted rate ratiosH1N1 influenza vaccineMedical record reviewVaccine coverage dataInfluenza vaccination campaignGBS incidencePH1N1 vaccinationInfluenza vaccineMonovalent vaccineRecord reviewIncident casesVaccine dosesExcess riskPatient interviewsGBS riskVaccine campaignVaccine historyVaccination campaignReduced Influenza Antiviral Treatment Among Children and Adults Hospitalized With Laboratory-Confirmed Influenza Infection in the Year After the 2009 Pandemic
Garg S, Chaves SS, Pérez A, D'Mello T, Gershman K, Meek J, Yousey-Hindes K, Arnold KE, Farley MM, Tengelsen L, Ryan P, Sharangpani R, Lynfield R, Morin C, Baumbach J, Hancock EB, Zansky S, Bennett NM, Fowler B, Bradley K, Thomas A, Cooper T, Schaffner W, Boulton R, Finelli L, Fry AM. Reduced Influenza Antiviral Treatment Among Children and Adults Hospitalized With Laboratory-Confirmed Influenza Infection in the Year After the 2009 Pandemic. Clinical Infectious Diseases 2012, 55: e18-e21. PMID: 22543024, DOI: 10.1093/cid/cis442.Peer-Reviewed Original Research
2011
Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007 - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC
Hirshon JM, Thompson AD, Limbago B, McDonald LC, Bonkosky M, Heimer R, Meek J, Mai V, Braden C. Clostridium difficile Infection in Outpatients, Maryland and Connecticut, USA, 2002–2007 - Volume 17, Number 10—October 2011 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2011, 17: 1946-1949. PMID: 22000379, PMCID: PMC3310666, DOI: 10.3201/eid1710.110069.Peer-Reviewed Original ResearchChildren With Asthma Hospitalized With Seasonal or Pandemic Influenza, 2003–2009
Dawood F, Kamimoto L, D'Mello T, Reingold A, Gershman K, Meek J, Arnold K, Farley M, Ryan P, Lynfield R, Morin C, Baumbach J, Zansky S, Bennett N, Thomas A, Schaffner W, Kirschke D, Finelli L. Children With Asthma Hospitalized With Seasonal or Pandemic Influenza, 2003–2009. Pediatrics 2011, 128: e27-e32. PMID: 21646257, DOI: 10.1542/peds.2010-3343.Peer-Reviewed Original ResearchConceptsPandemic H1N1 influenzaAdditional medical conditionsAsthmatic childrenClinical courseInfluenza seasonH1N1 influenzaMedical conditionsLaboratory-confirmed influenzaAsthma exacerbationsRespiratory failureAsthma severityMedian ageInfluenza BInfluenza preventionIntensive careSeasonal influenzaMedical historyMedical recordsInfluenza AInfluenza typeAsthmaInfluenzaCare occurSubstantial proportionComplications
2010
Influenza-Associated Pneumonia in Children Hospitalized With Laboratory-Confirmed Influenza, 2003–2008
Dawood FS, Fiore A, Kamimoto L, Nowell M, Reingold A, Gershman K, Meek J, Hadler J, Arnold KE, Ryan P, Lynfield R, Morin C, Baumbach J, Zansky S, Bennett NM, Thomas A, Schaffner W, Kirschke D, Finelli L. Influenza-Associated Pneumonia in Children Hospitalized With Laboratory-Confirmed Influenza, 2003–2008. The Pediatric Infectious Disease Journal 2010, 29: 585-590. PMID: 20589966, PMCID: PMC5856105, DOI: 10.1097/inf.0b013e3181d411c5.Peer-Reviewed Original ResearchConceptsInfluenza-associated pneumoniaChest radiographsHospitalized childrenIntensive care unit admissionCare unit admissionLaboratory-confirmed influenzaSevere clinical courseInfluenza complicationsUnit admissionRespiratory failureCommon complicationClinical courseInfluenza seasonTreatment strategiesPneumoniaMultivariate analysisNew pneumoniaGreater riskInfluenzaRadiographsAge 6Age 2HospitalizationAsthmaComplicationsBurden of Seasonal Influenza Hospitalization in Children, United States, 2003 to 2008
Dawood FS, Fiore A, Kamimoto L, Bramley A, Reingold A, Gershman K, Meek J, Hadler J, Arnold KE, Ryan P, Lynfield R, Morin C, Mueller M, Baumbach J, Zansky S, Bennett NM, Thomas A, Schaffner W, Kirschke D, Finelli L, Network E. Burden of Seasonal Influenza Hospitalization in Children, United States, 2003 to 2008. The Journal Of Pediatrics 2010, 157: 808-814. PMID: 20580018, DOI: 10.1016/j.jpeds.2010.05.012.Peer-Reviewed Original ResearchConceptsSevere outcomesInfluenza hospitalizationsHospitalization ratesHospitalized childrenEmerging Infections Program NetworkIntensive care unit admissionInfections Program NetworkSeasonal influenza hospitalizationsCare unit admissionLaboratory-confirmed influenzaPopulation-based surveillanceUnderlying medical conditionsHigher hospitalization ratesRate of hospitalizationProportion of childrenRapid diagnostic testsUnit admissionRespiratory failureBacterial coinfectionClinical courseHospital recordsSeasonal influenzaMedical historyDisease burdenIncidence rate
2009
Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study
Connally NP, Durante AJ, Yousey-Hindes KM, Meek JI, Nelson RS, Heimer R. Peridomestic Lyme Disease Prevention Results of a Population-Based Case–Control Study. American Journal Of Preventive Medicine 2009, 37: 201-206. PMID: 19595558, DOI: 10.1016/j.amepre.2009.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnimalsCase-Control StudiesChildChild, PreschoolConnecticutEnvironment DesignEnvironmental ExposureFemaleHumansHygieneInfantLogistic ModelsLyme DiseaseMaleMatched-Pair AnalysisMiddle AgedPopulation SurveillanceProspective StudiesResidence CharacteristicsRisk FactorsSurveys and QuestionnairesTicksYoung AdultConceptsCase-control studyLyme diseaseDisease prevention initiativesConditional logistic regressionDisease prevention measuresErythema migransPotential confoundersRecreational exposureLogistic regressionProspective ageDiseaseCase onsetPrevention resultsPrevention measuresPersonal protectionRiskHoursConfoundersMigransTicksInfectionStudyConnecticut communitiesMonths
2008
Performance of an Algorithm for Assessing Smallpox Risk among Patients with Rashes That May Be Confused with Smallpox
Hutchins S, Sulemana I, Heilpern K, Schaffner W, Wax G, Lerner E, Watson B, Baltimore R, Waltenburg R, Aronsky D, Coffin S, Ng G, Craig A, Behrman A, Meek J, Sherman E, Chavez S, Harpaz R, Schmid S. Performance of an Algorithm for Assessing Smallpox Risk among Patients with Rashes That May Be Confused with Smallpox. Clinical Infectious Diseases 2008, 46: s195-s203. PMID: 18284359, DOI: 10.1086/524383.Peer-Reviewed Original Research
2001
Retrospective validation of a surveillance system for unexplained illness and death: New Haven County, Connecticut.
Kluger M, Sofair A, Heye C, Meek J, Sodhi R, Hadler J. Retrospective validation of a surveillance system for unexplained illness and death: New Haven County, Connecticut. American Journal Of Public Health 2001, 91: 1214-9. PMID: 11499106, PMCID: PMC1446748, DOI: 10.2105/ajph.91.8.1214.Peer-Reviewed Original ResearchConceptsActive prospective surveillanceInfectious causesUnexplained illnessProspective surveillanceRetrospective surveillanceRetrospective validationProspective surveillance systemHospital discharge dataSurveillance systemSuch patientsAnnual incidenceStudy criteriaMedical recordsNew Haven CountyComputerized searchIllnessLess labor-intensive alternativeDeathLabor-intensive alternativePatientsReference populationSurveillanceCauseDischarge dataStudy counties
2000
The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis
IJdo J, Meek J, Cartter M, Magnarelli L, Wu C, Tenuta S, Fikrig E, Ryder R. The Emergence of Another Tickborne Infection in the 12-Town Area around Lyme, Connecticut: Human Granulocytic Ehrlichiosis. The Journal Of Infectious Diseases 2000, 181: 1388-1393. PMID: 10751139, DOI: 10.1086/315389.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisTickborne infectionProspective population-based surveillanceGranulocytic ehrlichiosisCommon tickborne infectionPopulation-based surveillancePrimary care providersSubset of seraIndirect fluorescent antibody methodIllness suggestiveCare providersLaboratory evidenceImportant causeProbable casesFluorescent antibody methodImmunoblot assayLyme diseaseInfectionAntibody methodIncidenceEhrlichiosisLymeMorbidityDiseaseSuggestive