2023
Effect of a Home Health and Safety Intervention on Emergency Department Use in the Frail Elderly: A Prospective Observational Study
Bogucki S, Siddiqui G, Carter R, McGovern J, Dziura J, Gan G, Li F, Stover G, Cone D, Brokowski C, Joseph D. Effect of a Home Health and Safety Intervention on Emergency Department Use in the Frail Elderly: A Prospective Observational Study. Western Journal Of Emergency Medicine 2023, 0: 522-531. PMID: 37278776, PMCID: PMC10284516, DOI: 10.5811/westjem.58378.Peer-Reviewed Original ResearchConceptsProspective observational studyED utilizationObservational studySubsequent ED utilizationEmergency department useEmergency department utilizationHome health nursesOutcomes of interestHome health programsLimited statistical powerSubsequent EDED evaluationStudy armsGeriatric patientsDepartment useHealth nursesFall riskStudy interventionHome visitsHome healthFrail ElderlyCognitive declineUseful markerHealth programsFrailty
2022
Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women
Gaffey AE, Rosman L, Sico JJ, Haskell SG, Brandt CA, Bathulapalli H, Han L, Dziura J, Skanderson M, Burg MM. Military sexual trauma and incident hypertension: a 16-year cohort study of young and middle-aged men and women. Journal Of Hypertension 2022, 40: 2307-2315. PMID: 35983872, DOI: 10.1097/hjh.0000000000003267.Peer-Reviewed Original ResearchConceptsIncident hypertensionRisk factorsPsychiatric disordersMultivariate Cox proportional hazards modelVeterans Health Administration dataGreater riskCox proportional hazards modelTrauma-related psychiatric disordersMiddle-aged veteransCardiovascular risk factorsBaseline blood pressureElevated cardiovascular riskLarge prospective cohortHealth Administration dataMiddle-aged menProportional hazards modelSex-specific analysesPosttraumatic stress disorderMilitary sexual traumaCardiovascular riskCohort studyProspective cohortBlood pressureTreatment attenuatesCardiovascular impact
2021
Implantable Cardioverter Defibrillator Lead Survival in Athletic Patients
Link MS, Sullivan RM, Olshansky B, Cannom D, Berul CI, Hauser RG, Heidbuchel H, Jordaens L, Krahn AD, Morgan J, Patton KK, Saarel EV, Wilkoff BL, Li F, Dziura J, Brandt C, Barth C, Lampert R. Implantable Cardioverter Defibrillator Lead Survival in Athletic Patients. Circulation Arrhythmia And Electrophysiology 2021, 14: e009344. PMID: 33724879, DOI: 10.1161/circep.120.009344.Peer-Reviewed Original Research
2020
All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors
Gordon K, Manhapra A, Crystal S, Dziura J, Edelman E, Skanderson M, Kerns R, Justice A, Tate J, Becker W. All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors. Drug And Alcohol Dependence 2020, 216: 108291. PMID: 33011662, PMCID: PMC7644145, DOI: 10.1016/j.drugalcdep.2020.108291.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseCause mortalityLong-term opioid therapyTime-updated Cox regressionStrong dose-response relationshipUnnatural deathsEquivalent daily doseDose-response relationshipOpioid doseOpioid therapyUninfected patientsOpioid useDaily doseCox regressionMortality outcomesTherapy doseHigh doseMale veteransOverdose fatalitiesOverdose mortalityPLWHMortalityHIVPatientsDose
2019
Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults
Rosman L, Sico JJ, Lampert R, Gaffey AE, Ramsey CM, Dziura J, Chui PW, Cavanagh CE, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Stroke in Young and Middle-Aged Adults. Stroke 2019, 50: 2996-3003. PMID: 31619151, DOI: 10.1161/strokeaha.119.026854.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIncident transient ischemic attackPosttraumatic stress disorderEffects of PTSDIschemic strokeIncident strokeHealthcare utilizationIncidence of TIAStress disorderYoung adultsMiddle-aged veteransStroke risk factorsMultivariate Cox modelIschemic stroke riskAge-specific prevention strategiesVeterans Health AdministrationMiddle-aged adultsIschemic attackStroke riskPsychological factorsUnadjusted analysesRisk factorsEffect modificationCox modelPsychiatric disordersPosttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults
Rosman L, Lampert R, Ramsey CM, Dziura J, Chui PW, Brandt C, Haskell S, Burg MM. Posttraumatic Stress Disorder and Risk for Early Incident Atrial Fibrillation: A Prospective Cohort Study of 1.1 Million Young Adults. Journal Of The American Heart Association 2019, 8: e013741. PMID: 31564191, PMCID: PMC6806049, DOI: 10.1161/jaha.119.013741.Peer-Reviewed Original ResearchConceptsIncident atrial fibrillationPosttraumatic stress disorderMiddle-aged veteransAtrial fibrillationRisk factorsMultivariate Cox proportional hazards modelIncidence of AFCox proportional hazards modelStress disorderAF risk factorsCardiovascular risk factorsNew atrial fibrillationProspective cohort studyHigher overall incidenceVeterans Health AdministrationProportional hazards modelAcute psychological stressChronic stress syndromeCohort studyOverall incidenceAtrial tachycardiaLifestyle factorsAtrial flutterHealthcare useEffect modificationEffect of β-blockers on triggering of symptomatic atrial fibrillation by anger or stress
Lampert R, Burg MM, Jamner LD, Dziura J, Brandt C, Li F, Donovan T, Soufer R. Effect of β-blockers on triggering of symptomatic atrial fibrillation by anger or stress. Heart Rhythm 2019, 16: 1167-1173. PMID: 31171436, PMCID: PMC6759206, DOI: 10.1016/j.hrthm.2019.03.004.Peer-Reviewed Original ResearchConceptsAtrial fibrillationΒ-blockersAF episodesHistory of AFControl periodSymptomatic AF episodesSymptomatic atrial fibrillationΒ-blocker useExclusion of patientsPersistent atrial fibrillationHolter monitoringAF symptomsPatientsPatient exposureCase periodFibrillationMood statesEpisodesEvent monitorDeleterious physiological responsesExposurePhysiological responsesDiary dataSotalol
2018
Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators
Saarel EV, Law I, Berul CI, Ackerman MJ, Kanter RJ, Sanatani S, Cohen MI, Berger S, Fischbach PS, Burton DA, Dziura J, Brandt C, Simone L, Li F, Olshansky B, Cannom DS, Lampert RJ. Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators. Circulation Arrhythmia And Electrophysiology 2018, 11: e006305. PMID: 30520349, DOI: 10.1161/circep.118.006305.Peer-Reviewed Original ResearchConceptsYounger patientsLead malfunctionEnd pointSafety of sportsVentricular fibrillation stormPrimary end pointSecondary end pointsSerious adverse eventsMedical record reviewSerious adverse sequelaeCongenital heart diseaseOccurrence of deathImplantable cardioverter defibrillatorLong QT syndromeAdverse eventsICD shocksAdverse sequelaeClinical outcomesCommon diagnosisMultinational registryRecord reviewVentricular arrhythmiasICD populationMean ageClinical detailsCompetitive athletes with implantable cardioverter–defibrillators—How to program? Data from the Implantable Cardioverter–Defibrillator Sports Registry
Olshansky B, Atteya G, Cannom D, Heidbuchel H, Saarel EV, Anfinsen OG, Cheng A, Gold MR, Müssigbrodt A, Patton KK, Saxon LA, Wilkoff BL, Willems R, Dziura J, Li F, Brandt C, Simone L, Wilhelm M, Lampert R. Competitive athletes with implantable cardioverter–defibrillators—How to program? Data from the Implantable Cardioverter–Defibrillator Sports Registry. Heart Rhythm 2018, 16: 581-587. PMID: 30389442, DOI: 10.1016/j.hrthm.2018.10.032.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAthletesChildDeath, Sudden, CardiacDefibrillators, ImplantableFemaleHumansMaleMiddle AgedProspective StudiesRegistriesConceptsHigh-rate cutoffTransient lossICD shocksRisk of totalInappropriate ICD shocksLonger detection intervalsDual-chamber devicesRisk of shockAppropriate shocksVentricular tachycardiaInappropriate shocksInternational registrySudden deathCompetitive athletesRate cutoffICDOccurrence of shockPatientsAthletesRegistryRiskLonger detectionDeathDetection rateTotal shocksPresentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study
Safdar B, Spatz ES, Dreyer RP, Beltrame JF, Lichtman JH, Spertus JA, Reynolds HR, Geda M, Bueno H, Dziura JD, Krumholz HM, D'Onofrio G. Presentation, Clinical Profile, and Prognosis of Young Patients With Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): Results From the VIRGO Study. Journal Of The American Heart Association 2018, 7: e009174. PMID: 29954744, PMCID: PMC6064896, DOI: 10.1161/jaha.118.009174.Peer-Reviewed Original ResearchConceptsMI-CAD patientsNonobstructive coronary arteriesMI-CADYounger patientsClinical profileCoronary arteryMyocardial infarctionTraditional cardiac risk factorsAcute myocardial infarction patientsCardiac risk factorsGestational diabetes mellitusMyocardial infarction patientsTimes higher oddsMINOCA patientsSAQ qualityVIRGO StudyClinical characteristicsHypercoaguable stateDiabetes mellitusObstructive diseaseClinical outcomesInfarction patientsRisk factorsMINOCAPsychosocial status“To Err Is Human” but Disclosure Must be Taught
Crimmins AC, Wong AH, Bonz JW, Tsyrulnik A, Jubanyik K, Dziura JD, Dodge KL, Evans LV. “To Err Is Human” but Disclosure Must be Taught. Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2018, 13: 107-116. PMID: 29346222, DOI: 10.1097/sih.0000000000000273.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmergency MedicineFemaleHumansMaleMedical ErrorsPatient SimulationProspective StudiesTruth DisclosureConceptsError disclosurePractice guidelinesEmergency medicineMedical studentsMedical error disclosurePatient-centered careSenior EM residentsAttending EM physiciansLevels of clinical experienceIncreasing physician experienceProspective cohort studyLevel of trainingImmersive simulation scenariosEM physiciansEM residentsHealthcare providersSafe practice guidelinesPhysician experienceAttending physiciansAdverse eventsCohort studySuboptimal adherenceTotal scorePromote safetyProviders
2017
Depression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department
Kim Y, Soffler M, Paradise S, Jelani QU, Dziura J, Sinha R, Safdar B. Depression is associated with recurrent chest pain with or without coronary artery disease: A prospective cohort study in the emergency department. American Heart Journal 2017, 191: 47-54. PMID: 28888269, DOI: 10.1016/j.ahj.2017.06.003.Peer-Reviewed Original ResearchConceptsRecurrent chest painCoronary artery diseaseAcute chest painChest painProspective cohort studyChest pain centerClinical Anxiety ScaleEmergency departmentPerceived Stress ScalePain centerCohort studyArtery diseaseNonobstructive coronary artery diseaseObstructive coronary artery diseaseChest pain recurrenceED chest painCardiac risk factorsCardiac stress testingPatient Health QuestionnaireSignificant independent predictorsStress testingMultivariable regression modelsPain recurrenceIndependent predictorsPrimary outcome
2014
Triggering of Symptomatic Atrial Fibrillation by Negative Emotion
Lampert R, Jamner L, Burg M, Dziura J, Brandt C, Liu H, Li F, Donovan T, Soufer R. Triggering of Symptomatic Atrial Fibrillation by Negative Emotion. Journal Of The American College Of Cardiology 2014, 64: 1533-1534. PMID: 25277622, DOI: 10.1016/j.jacc.2014.07.959.Peer-Reviewed Original ResearchThe Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations
Lang SM, Syed MA, Dziura J, Rocco E, Kirshbom P, Bhandari V, Giuliano JS. The Effect of Modified Ultrafiltration on Angiopoietins in Pediatric Cardiothoracic Operations. The Annals Of Thoracic Surgery 2014, 98: 1699-1704. PMID: 25258157, PMCID: PMC4253712, DOI: 10.1016/j.athoracsur.2014.06.053.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionModified ultrafiltrationUnit admissionCardiopulmonary bypassAngpt-2Interleukin-8Proinflammatory mediatorsClinical benefitAngpt-2 concentrationsInterleukin-10 levelsProspective cohort studySystemic inflammatory responseChildren 18 yearsEnzyme-linked immunosorbentCohort studyAntiinflammatory mediatorsInterleukin-10Inflammatory responseAngiopoietin-2Angpt-1Cardiothoracic operationsPatient's bloodAdmissionCytokine removalMood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery
Hamid H, Blackmon K, Cong X, Dziura J, Atlas LY, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Devinsky O. Mood, anxiety, and incomplete seizure control affect quality of life after epilepsy surgery. Neurology 2014, 82: 887-894. PMID: 24489129, PMCID: PMC3959755, DOI: 10.1212/wnl.0000000000000183.Peer-Reviewed Original ResearchConceptsBeck Depression InventorySeizure controlOverall QOL scoreEpilepsy surgeryQuality of lifeBeck Anxiety InventoryQOL scoresOverall QoLBAI scoresMixed-model repeated-measures analysisPartial seizure controlGood seizure controlPoor seizure controlAssociation of depressionComprehensive diagnostic workupEpilepsy Inventory-89Incomplete seizure controlManagement of moodRepeated-measures analysisQoL subscoresSeizure outcomeEpilepsy centersWorse QoLDiagnostic workupPostsurgical care
2013
Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators
Lampert R, Olshansky B, Heidbuchel H, Lawless C, Saarel E, Ackerman M, Calkins H, Estes NA, Link MS, Maron BJ, Marcus F, Scheinman M, Wilkoff BL, Zipes DP, Berul CI, Cheng A, Law I, Loomis M, Barth C, Brandt C, Dziura J, Li F, Cannom D. Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators. Circulation 2013, 127: 2021-2030. PMID: 23690453, DOI: 10.1161/circulationaha.112.000447.Peer-Reviewed Original ResearchConceptsPhysical activityImplantable cardioverter defibrillator patientsSafety of sportsCardioverter-defibrillator patientsVentricular arrhythmia episodesImplantable cardioverter defibrillatorSports participationHigh-risk sportsAppropriate shocksMedian ageClinical outcomesVentricular arrhythmiasInformed physicianMedical recordsClinical dataLead malfunctionCardioverter defibrillatorCommon sportsArrhythmia episodesPatient decisionCompetitive athletesPrimary endArrhythmiasICDPhone interviews
2011
Long-term association between seizure outcome and depression after resective epilepsy surgery
Hamid H, Liu H, Cong X, Devinsky O, Berg AT, Vickrey BG, Sperling MR, Shinnar S, Langfitt JT, Walczak TS, Barr WB, Dziura J, Bazil CW, Spencer SS. Long-term association between seizure outcome and depression after resective epilepsy surgery. Neurology 2011, 77: 1972-1976. PMID: 22094480, PMCID: PMC3235357, DOI: 10.1212/wnl.0b013e31823a0c90.Peer-Reviewed Original ResearchMeSH KeywordsAdultComorbidityDepressive DisorderEpilepsyFemaleHumansMaleMiddle AgedProspective StudiesSurvival AnalysisConceptsSeizure control groupExcellent seizure controlResective epilepsy surgerySeizure controlBeck Depression InventoryDepressive symptomsControl groupEpilepsy surgeryBDI scoresMixed-model repeated-measures analysisBorderline significant reductionEpilepsy surgery outcomeGood seizure controlMulticenter prospective studyLong-term improvementRepeated-measures analysisSeizure outcomeResective surgeryProspective studySurgery outcomesSevere depressionMean changeInitial improvementSurgeryCase status
2009
Translating the Diabetes Prevention Program to Primary Care
Whittemore R, Melkus G, Wagner J, Dziura J, Northrup V, Grey M. Translating the Diabetes Prevention Program to Primary Care. Nursing Research 2009, 58: 2-12. PMID: 19092550, PMCID: PMC2689783, DOI: 10.1097/nnr.0b013e31818fcef3.Peer-Reviewed Original ResearchMeSH KeywordsAdultDiabetes Mellitus, Type 2FemaleHumansHypercholesterolemiaHypertensionLife StyleMaleMiddle AgedNew EnglandNurse PractitionersNursing Evaluation ResearchNutritional SciencesObesityPatient Education as TopicPatient SatisfactionPilot ProjectsPrimary Health CareProgram EvaluationProspective StudiesSingle-Blind MethodConceptsStandard care participantsType 2 diabetesLifestyle programNurse practitionersHigh-density lipoproteinPrimary careCare participantsLifestyle change programDiabetes Prevention ProgramExercise behaviorMixed-model repeated-measures analysisRisk of diabetesStandard care programmeRepeated-measures analysisLifestyle participantsTreatment goalsCare programPrevention programsClinical settingPsychosocial strategiesDiabetesLow-income sampleWeight lossMotivational interviewingCare
2008
Socioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass
Akkary E, Nerlinger A, Yu S, Dziura J, Duffy AJ, Bell RL. Socioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass. Surgical Endoscopy 2008, 23: 1246-1251. PMID: 18813989, DOI: 10.1007/s00464-008-0138-z.Peer-Reviewed Original ResearchConceptsBody mass indexInitial body mass indexPostoperative weight lossWeight lossLaparoscopic RouxBMI decreaseSocioeconomic statusInitial mean body mass indexMedian household incomeMean body mass indexPrivate insuranceAppropriate patient selectionPrivate insurance groupPostoperative behavioral changesInsurance carriersProspective databaseGastric bypassPatient demographicsSingle surgeonMass indexPatient selectionGroup APatientsLRYGBHousehold income
2006
Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial
Banaszewska B, Pawelczyk L, Spaczynski RZ, Dziura J, Duleba AJ. Effects of Simvastatin and Oral Contraceptive Agent on Polycystic Ovary Syndrome: Prospective, Randomized, Crossover Trial. The Journal Of Clinical Endocrinology & Metabolism 2006, 92: 456-461. PMID: 17105841, DOI: 10.1210/jc.2006-1988.Peer-Reviewed Original ResearchConceptsOral contraceptive pillsPolycystic ovary syndromeLow-density lipoprotein cholesterolTotal testosteroneLipoprotein cholesterolOvary syndromeSystemic inflammationCrossover trialSoluble vascular cell adhesion molecule-1Treatment of PCOSVascular cell adhesion molecule-1Ovarian theca-interstitial cellsCell adhesion molecule-1Oral contraceptive agentsSerum total testosteronePrimary outcome measureC-reactive proteinEffect of simvastatinTheca-interstitial cellsAdhesion molecule-1Academic medical centerRandom-effects modelCardiovascular riskFree testosteroneTotal cholesterol